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. 1981 May;38(2):556–563. doi: 10.1128/jvi.38.2.556-563.1981

Organization of viral genome in a T antigen-negative hamster tumor induced by human papovavirus BK.

Y Yogo, A Furuno, A Nozawa, S Uchida
PMCID: PMC171186  PMID: 6264127

Abstract

We analyzed by blot hybridization the state and structure of the viral DNA in an exceptional BK virus-induced hamster tumor (choroid plexus papilloma Vn-324) that contains about one copy of the BK virus genome per cell, but no intranuclear T antigen as assayed by indirect immunofluorescence. The BK viral DNA was found to be integrated into cellular DNA at a site in the middle of the early region of the viral genome (between 0.32 and 0.41 map units). The structure of the inserted viral DNA shows that it cannot encode a full-size large T antigen, but may encode small T antigen and an N-terminal portion of large T antigen.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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