Skip to main content
PMC home page
Clinical and Experimental Immunology logoLink to Clinical and Experimental Immunology
. 1971 Sep;9(3):355–358.

The transfer of human IgG subclasses from mother to foetus

F C Hay, M G R Hull, G Torrigiani
PMCID: PMC1713070  PMID: 4998969

Abstract

The concentration of IgG subclasses was measured in matched pairs of maternal and cord serum by single radial immunodiffusion. IgG1, IgG3 and IgG4 were present in similar amounts in both the mothers and infants. IgG2 was present in the mothers at about 3 times the amount in the cord blood.

Full text

PDF
356

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BRIDGES R. A., CONDIE R. M., ZAK S. J., GOOD R. A. The morphologic basis of antibody formation development during the neonatal period. J Lab Clin Med. 1959 Mar;53(3):331–357. [PubMed] [Google Scholar]
  2. FUDENBERG H. H. GM GENES AND GAMMA-G-GLOBULIN SYNTHESIS IN THE HUMAN FETUS. J Immunol. 1965 Apr;94:514–520. [PubMed] [Google Scholar]
  3. GITLIN D., KUMATE J., URRUSTI J., MORALES C. THE SELECTIVITY OF THE HUMAN PLACENTA IN THE TRANSFER OF PLASMA PROTEINS FROM MOTHER TO FETUS. J Clin Invest. 1964 Oct;43:1938–1951. doi: 10.1172/JCI105068. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. GRUBB R., LAURELL A. B. Hereditary serological human serum groups. Acta Pathol Microbiol Scand. 1956;39(6):390–398. doi: 10.1111/j.1699-0463.1956.tb05067.x. [DOI] [PubMed] [Google Scholar]
  5. HUNGER H., THIERBACH V. GM(A)-BESTIMMUNGEN BEI MUETTERN UND NEUGEBORENEN. Blut. 1963 Dec;9:385–388. [PubMed] [Google Scholar]
  6. LINNET-JEPSEN P., GALATIUS-JENSEN F., HAUGE M. On the inheritance of the Gm serum group. Acta Genet Stat Med. 1958;8(2):164–196. doi: 10.1159/000151065. [DOI] [PubMed] [Google Scholar]
  7. Mancini G., Carbonara A. O., Heremans J. F. Immunochemical quantitation of antigens by single radial immunodiffusion. Immunochemistry. 1965 Sep;2(3):235–254. doi: 10.1016/0019-2791(65)90004-2. [DOI] [PubMed] [Google Scholar]
  8. ROWE D. S., FAHEY J. L. A NEW CLASS OF HUMAN IMMUNOGLOBULINS. II. NORMAL SERUM IGD. J Exp Med. 1965 Jan 1;121:185–199. doi: 10.1084/jem.121.1.185. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Ropartz C., Rivat L., Rousseau P. Y. La transmission des facteurs Gm et Inv de la mère à l'enfant nouveau-né. Ann Genet. 1965;8(1):39–43. [PubMed] [Google Scholar]
  10. Wang A. C., Faulk W. P., Stuckey M. A., Fudenberg H. H. Chemical differences of adult, fetal and hypogammaglobulinemic IgG immunoglobulins. Immunochemistry. 1970 Aug;7(8):703–708. doi: 10.1016/0019-2791(70)90176-x. [DOI] [PubMed] [Google Scholar]
  11. ZAK S. J., GOOD R. A. Immunochemical studies of human serum gamma globulins. J Clin Invest. 1959 Mar;38(3):579–586. doi: 10.1172/JCI103835. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Clinical and Experimental Immunology are provided here courtesy of British Society for Immunology

RESOURCES