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. 1988 Nov;43(5):684–688.

Linkage studies in a large fragile X family.

M Patterson 1, M Bell 1, W Kress 1, K E Davies 1, U Froster-Iskenius 1
PMCID: PMC1715522  PMID: 2903666

Abstract

We have analyzed the segregation of five loci in the region Xq27/28 in a large family affected by the fragile X syndrome. The marker DXS115 (767) is shown to be polymorphic with the enzyme PstI, as well as with BstXI. This marker will be useful in the analysis of both fragile X and haemophilia A families. The data presented here are consistent with the following order of loci: Xcen-F9-DXS105(cX55.7,55E)-DXS98(4D-8)- FRAXA-DXS52(St14)-DXS115(767)-qter.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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