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. 1997 Dec;61(6):1459–1460. doi: 10.1086/301640

The frequency of the methylenetetrahydrofolate reductase-gene mutation varies with age in the normal population.

S Matsushita, T Muramatsu, H Arai, T Matsui, S Higuchi

PMCID: PMC1716067 PMID: 9399898

1459

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

Boushey C. J., Beresford S. A., Omenn G. S., Motulsky A. G. A quantitative assessment of plasma homocysteine as a risk factor for vascular disease. Probable benefits of increasing folic acid intakes. JAMA. 1995 Oct 4;274(13):1049–1057. doi: 10.1001/jama.1995.03530130055028. [DOI] [PubMed] [Google Scholar]
Engbersen A. M., Franken D. G., Boers G. H., Stevens E. M., Trijbels F. J., Blom H. J. Thermolabile 5,10-methylenetetrahydrofolate reductase as a cause of mild hyperhomocysteinemia. Am J Hum Genet. 1995 Jan;56(1):142–150. [PMC free article] [PubMed] [Google Scholar]
Frosst P., Blom H. J., Milos R., Goyette P., Sheppard C. A., Matthews R. G., Boers G. J., den Heijer M., Kluijtmans L. A., van den Heuvel L. P. A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase. Nat Genet. 1995 May;10(1):111–113. doi: 10.1038/ng0595-111. [DOI] [PubMed] [Google Scholar]
Kang S. S., Passen E. L., Ruggie N., Wong P. W., Sora H. Thermolabile defect of methylenetetrahydrofolate reductase in coronary artery disease. Circulation. 1993 Oct;88(4 Pt 1):1463–1469. doi: 10.1161/01.cir.88.4.1463. [DOI] [PubMed] [Google Scholar]
Kluijtmans L. A., van den Heuvel L. P., Boers G. H., Frosst P., Stevens E. M., van Oost B. A., den Heijer M., Trijbels F. J., Rozen R., Blom H. J. Molecular genetic analysis in mild hyperhomocysteinemia: a common mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for cardiovascular disease. Am J Hum Genet. 1996 Jan;58(1):35–41. [PMC free article] [PubMed] [Google Scholar]

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