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. 1990 May;34(5):901–903. doi: 10.1128/aac.34.5.901

In vitro activities of vancomycin and teicoplanin against coagulase-negative staphylococci isolated from neutropenic patients.

J Maugein 1, J L Pellegrin 1, G Brossard 1, J Fourche 1, B Leng 1, J Reiffers 1
PMCID: PMC171715  PMID: 2141781

Abstract

This study reports the in vitro activities of vancomycin and teicoplanin against 185 coagulase-negative staphylococcal strains isolated from 80 neutropenic patients who received different antibiotic treatments. All strains were susceptible to vancomycin: MICs for 50 and 90% of strains tested were 2 and 4 mg/liter, respectively. Teicoplanin was less active, and MICs displayed a wider range. For only teicoplanin was there a correlation between resistance and previous treatment. At the 4- and 32-mg/liter breakpoint levels, only 20% of the strains isolated from patients without glycopeptide treatment were intermediate or resistant, whereas 49.2% of the strains from patients who had received vancomycin or teicoplanin or both were intermediate or resistant.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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