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. 1990 Jun;34(6):1244–1248. doi: 10.1128/aac.34.6.1244

Dissemination of amikacin resistance gene aphA6 in Acinetobacter spp.

T Lambert 1, G Gerbaud 1, P Bouvet 1, J F Vieu 1, P Courvalin 1
PMCID: PMC171792  PMID: 2168146

Abstract

The distribution of the aphA6 gene, encoding a 3'-aminoglycoside phosphotransferase type VI, was studied by dot blot hybridization with 115 amikacin-resistant Acinetobacter strains from various geographical areas. Nucleotide sequences related to aphA6 were found in 109 strains belonging to seven species. As inferred from results of Southern hybridization, dissemination of amikacin resistance in Acinetobacter spp. is due to a gene rather than a strain or plasmid epidemic.

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Selected References

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