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. 1990 Sep;34(9):1862–1863. doi: 10.1128/aac.34.9.1862

Increasing resistance of Staphylococcus aureus to ciprofloxacin.

T E Daum 1, D R Schaberg 1, M S Terpenning 1, W S Sottile 1, C A Kauffman 1
PMCID: PMC171950  PMID: 2285306

Abstract

We demonstrated the marked emergence of resistance to ciprofloxacin among Staphylococcus arueus strains isolated at the Ann Arbor Veterans Administration Medical Center. All S. aureus isolates tested from 1984 to 1985 were susceptible, whereas 55.1% of methicillin-resistant and 2.5% of methicillin-susceptible strains from 1989 had high-level resistance to ciprofloxacin.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bacon A. E., Jorgensen K. A., Wilson K. H., Kauffman C. A. Emergence of nosocomial methicillin-resistant Staphylococcus aureus and therapy of colonized personnel during a hospital-wide outbreak. Infect Control. 1987 Apr;8(4):145–150. doi: 10.1017/s0195941700065802. [DOI] [PubMed] [Google Scholar]
  2. Cederna J. E., Terpenning M. S., Ensberg M., Bradley S. F., Kauffman C. A. Staphylococcus aureus nasal colonization in a nursing home: eradication with mupirocin. Infect Control Hosp Epidemiol. 1990 Jan;11(1):13–16. doi: 10.1086/646072. [DOI] [PubMed] [Google Scholar]
  3. Humphreys H., Mulvihill E. Ciprofloxacin-resistant Staphylococcus aureus. Lancet. 1985 Aug 17;2(8451):383–383. doi: 10.1016/s0140-6736(85)92510-3. [DOI] [PubMed] [Google Scholar]
  4. Kotilainen P., Nikoskelainen J., Huovinen P. Emergence of ciprofloxacin-resistant coagulase-negative staphylococcal skin flora in immunocompromised patients receiving ciprofloxacin. J Infect Dis. 1990 Jan;161(1):41–44. doi: 10.1093/infdis/161.1.41. [DOI] [PubMed] [Google Scholar]
  5. Maple P., Hamilton-Miller J., Brumfitt W. Ciprofloxacin resistance in methicillin- and gentamicin-resistant Staphylococcus aureus. Eur J Clin Microbiol Infect Dis. 1989 Jul;8(7):622–624. doi: 10.1007/BF01968141. [DOI] [PubMed] [Google Scholar]
  6. Mulligan M. E., Ruane P. J., Johnston L., Wong P., Wheelock J. P., MacDonald K., Reinhardt J. F., Johnson C. C., Statner B., Blomquist I. Ciprofloxacin for eradication of methicillin-resistant Staphylococcus aureus colonization. Am J Med. 1987 Apr 27;82(4A):215–219. [PubMed] [Google Scholar]
  7. Neu H. C. Ciprofloxacin: an overview and prospective appraisal. Am J Med. 1987 Apr 27;82(4A):395–404. [PubMed] [Google Scholar]
  8. Schaefler S. Methicillin-resistant strains of Staphylococcus aureus resistant to quinolones. J Clin Microbiol. 1989 Feb;27(2):335–336. doi: 10.1128/jcm.27.2.335-336.1989. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Smith S. M., Eng R. H., Berman E. The effect of ciprofloxacin on methicillin-resistant Staphylococcus aureus. J Antimicrob Chemother. 1986 Mar;17(3):287–295. doi: 10.1093/jac/17.3.287. [DOI] [PubMed] [Google Scholar]
  10. Thornsberry C., McDougal L. K. Successful use of broth microdilution in susceptibility tests for methicillin-resistant (heteroresistant) staphylococci. J Clin Microbiol. 1983 Nov;18(5):1084–1091. doi: 10.1128/jcm.18.5.1084-1091.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Wolfson J. S., Hooper D. C. Fluoroquinolone antimicrobial agents. Clin Microbiol Rev. 1989 Oct;2(4):378–424. doi: 10.1128/cmr.2.4.378. [DOI] [PMC free article] [PubMed] [Google Scholar]

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