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. 1990 Nov;34(11):2277–2279. doi: 10.1128/aac.34.11.2277

Cloning and characterization of a DNA fragment that confers sulfonamide resistance in a serogroup B, serotype 15 strain of Neisseria meningitidis.

B E Kristiansen 1, P Rådström 1, A Jenkins 1, E Ask 1, B Facinelli 1, O Sköld 1
PMCID: PMC172039  PMID: 2127350

Abstract

By cloning studies and complementation experiments, the sulfonamide resistance gene of a serogroup B and serotype 15 (B:15) strain of Neisseria meningitidis was localized to a 1.2-kb chromosomal SspI fragment expressing a drug-resistant dihydropteroate synthase. The fragment hybridized to DNA from both resistant and susceptible strains, suggesting that the resistance gene is a variant of the normal gene for dihydropteroate synthase.

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Selected References

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