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. 1988 Feb;32(2):279–281. doi: 10.1128/aac.32.2.279

In vitro activity of LY146032 alone and in combination with other antibiotics against gram-positive bacteria.

E Debbia 1, A Pesce 1, G C Schito 1
PMCID: PMC172154  PMID: 2834999

Abstract

The antibacterial activity of LY146032 alone and in combination with other drugs was assayed against gram-positive isolates. Synergism was found when LY146032 was combined with netilmicin, amikacin, imipenem, and fosfomycin by both checkerboard and time-kill tests. Indifference predominated when LY146032 was combined with teicoplanin, vancomycin, and rifampin. Under no circumstances and with no combinations was an antagonistic effect detected.

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Selected References

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