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. 2004 May;89(3):F190–F192. doi: 10.1136/adc.2003.043661

Injury and repair in developing brain

F Vaccarino, L Ment
PMCID: PMC1721670  PMID: 15102716

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Figure 1 .

Figure 1

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Cells of the astrocyte lineage give rise to neurones in the postnatal subventricular zone (SVZ). In the normal SVZ, there is a steady state equilibrium in which stem cells (S) generate transit amplifying cells (C cells) and neuronal progenitor cells (A cells). C cells also generate astrocytes (B cells), and this can be increased by exogenous epidermal growth factor (EGF). Astrocytes are normally quiescent. The C and A cells divide with a cell cycle of 13 h. Stem cells, estimated to be about 1% of the rapidly dividing cells, may lineally derive from astrocytes through a dedifferentiation process, a process that may be enhanced by fibroblast growth factor 2 (FGF2).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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