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. 2001 Apr;85(4):474–476. doi: 10.1136/bjo.85.4.474

Cyclodiode laser therapy for painful, blind glaucomatous eyes

K Martin, D Broadway
PMCID: PMC1723939  PMID: 11264140

Abstract

AIMS—To determine the ability of cyclodiode laser treatment to relieve discomfort in painful blind glaucomatous eyes.
METHODS—30 eyes underwent cyclodiode to reduce intraocular pressure (IOP) and relieve pain. Patients graded their pre-cyclodiode and post-cyclodiode pain.
RESULTS—After a minimum follow up of 6 months, a single cyclodiode treatment lowered mean IOP from 51 mm Hg (95% CI plus or minus 3.7 mm Hg) to 26 mm Hg (95% CI plus or minus 5.8 mm Hg) providing pain relief in 73.3% (22/30). After retreatment of six eyes, mean IOP was reduced to 22 (95% CI plus or minus 5.3) mm Hg and pain relief was obtained in 96.7% (29/30). For eyes achieving pain relief after one treatment, IOP was reduced by >30% in 81.0% (17/21). For eyes not achieving pain relief after one treatment, IOP was reduced by >30% in only 22.2% (2/9) (p=0.0042, Fisher's exact test).
CONCLUSION—Cyclodiode was highly successful in providing pain relief in painful blind hypertensive glaucomatous eyes. The best predictor of successful pain relief was IOP reduction of > 30% from baseline.



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Figure 1  .

Figure 1  

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Pretreatment and post-treatment intraocular pressures following single and repeat cyclodiode therapy.

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Azuara-Blanco A., Dua H. S. Malignant glaucoma after diode laser cyclophotocoagulation. Am J Ophthalmol. 1999 Apr;127(4):467–469. doi: 10.1016/s0002-9394(98)00359-6. [DOI] [PubMed] [Google Scholar]
  2. Bloom P. A., Tsai J. C., Sharma K., Miller M. H., Rice N. S., Hitchings R. A., Khaw P. T. "Cyclodiode". Trans-scleral diode laser cyclophotocoagulation in the treatment of advanced refractory glaucoma. Ophthalmology. 1997 Sep;104(9):1508–1520. doi: 10.1016/s0161-6420(97)30109-2. [DOI] [PubMed] [Google Scholar]
  3. Brancato R., Carassa R. G., Bettin P., Fiori M., Trabucchi G. Contact transscleral cyclophotocoagulation with diode laser in refractory glaucoma. Eur J Ophthalmol. 1995 Jan-Mar;5(1):32–39. doi: 10.1177/112067219500500106. [DOI] [PubMed] [Google Scholar]
  4. Gupta N., Weinreb R. N. Diode laser transscleral cyclophotocoagulation. J Glaucoma. 1997 Dec;6(6):426–429. [PubMed] [Google Scholar]
  5. Hawkins T. A., Stewart W. C. One-year results of semiconductor transscleral cyclophotocoagulation in patients with glaucoma. Arch Ophthalmol. 1993 Apr;111(4):488–491. doi: 10.1001/archopht.1993.01090040080035. [DOI] [PubMed] [Google Scholar]
  6. Johnson S. M. Neurotrophic corneal defects after diode laser cycloablation. Am J Ophthalmol. 1998 Nov;126(5):725–727. doi: 10.1016/s0002-9394(98)00175-5. [DOI] [PubMed] [Google Scholar]
  7. Kosoko O., Gaasterland D. E., Pollack I. P., Enger C. L. Long-term outcome of initial ciliary ablation with contact diode laser transscleral cyclophotocoagulation for severe glaucoma. The Diode Laser Ciliary Ablation Study Group. Ophthalmology. 1996 Aug;103(8):1294–1302. doi: 10.1016/s0161-6420(96)30508-3. [DOI] [PubMed] [Google Scholar]
  8. Montanari P., Italia A., Marangoni P., Pinotti D., Miglior M. Diode laser trans-scleral cyclophotocoagulation in refractory glaucoma treatment. Acta Ophthalmol Scand Suppl. 1997;(224):38–38. doi: 10.1111/j.1600-0420.1997.tb00468.x. [DOI] [PubMed] [Google Scholar]
  9. Sabri K., Vernon S. A. Scleral perforation following trans-scleral cyclodiode. Br J Ophthalmol. 1999 Apr;83(4):502–503. doi: 10.1136/bjo.83.4.501c. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Spencer A. F., Vernon S. A. "Cyclodiode": results of a standard protocol. Br J Ophthalmol. 1999 Mar;83(3):311–316. doi: 10.1136/bjo.83.3.311. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Threlkeld A. B., Johnson M. H. Contact transscleral diode cyclophotocoagulation for refractory glaucoma. J Glaucoma. 1999 Feb;8(1):3–7. [PubMed] [Google Scholar]
  12. Todd K. H., Funk K. G., Funk J. P., Bonacci R. Clinical significance of reported changes in pain severity. Ann Emerg Med. 1996 Apr;27(4):485–489. doi: 10.1016/s0196-0644(96)70238-x. [DOI] [PubMed] [Google Scholar]
  13. Walland M. J. Diode laser cyclophotocoagulation: dose-standardized therapy in end-stage glaucoma. Aust N Z J Ophthalmol. 1998 May;26(2):135–139. doi: 10.1111/j.1442-9071.1998.tb01529.x. [DOI] [PubMed] [Google Scholar]
  14. Yap-Veloso M. I., Simmons R. B., Echelman D. A., Gonzales T. K., Veira W. J., Simmons R. J. Intraocular pressure control after contact transscleral diode cyclophotocoagulation in eyes with intractable glaucoma. J Glaucoma. 1998 Oct;7(5):319–328. [PubMed] [Google Scholar]
  15. Yarnitsky D., Sprecher E., Zaslansky R., Hemli J. A. Multiple session experimental pain measurement. Pain. 1996 Oct;67(2-3):327–333. doi: 10.1016/0304-3959(96)03110-7. [DOI] [PubMed] [Google Scholar]

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