Skip to main content
PMC home page
Bulletin of the New York Academy of Medicine logoLink to Bulletin of the New York Academy of Medicine
. 1975 Oct;51(9):1020–1038.

Principles of combination therapy.

S Levin, A A Harris
PMCID: PMC1749606  PMID: 1102002

Full text

PDF
1020

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. AHERN J. J., BURNELL J. M., KIRBY W. M. M. Lack of interference of chloramphenicol with penicillin in a hemolytic streptococcal infection in mice. Proc Soc Exp Biol Med. 1952 Apr;79(4):568–571. doi: 10.3181/00379727-79-19449. [DOI] [PubMed] [Google Scholar]
  2. Abramson I. J., Smibert R. M. Synergism of antibiotic combinations against treponemes. Br J Vener Dis. 1972 Apr;48(2):113–115. doi: 10.1136/sti.48.2.113. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Andriole V. T. Antibiotic synergy in experimental infection with Pseudomonas. II. The effect of carbenicillin, cephalothin, or cephanone combined with tobramycin or gentamicin. J Infect Dis. 1974 Feb;129(2):124–133. doi: 10.1093/infdis/129.2.124. [DOI] [PubMed] [Google Scholar]
  4. Barber M. Drug combinations in antibacterial chemotherapy. Proc R Soc Med. 1965 Nov;58(11 Pt 2):990–995. [PMC free article] [PubMed] [Google Scholar]
  5. Beggs W. H., Sarosi G. A., Andrews F. A. Synergistic action of amphotericin B and rifampin on Candida albicans. Am Rev Respir Dis. 1974 Nov;110(5):671–673. doi: 10.1164/arrd.1974.110.5.671. [DOI] [PubMed] [Google Scholar]
  6. Bell S. M., Smith D. D. Resistance of Pseudomonas aeruginosa to carbenicillin. Lancet. 1969 Apr 12;1(7598):753–754. doi: 10.1016/s0140-6736(69)91754-1. [DOI] [PubMed] [Google Scholar]
  7. Brodie B. B. Displacement of one drug by another from carrier or receptor sites. Proc R Soc Med. 1965 Nov;58(11 Pt 2):946–955. [PMC free article] [PubMed] [Google Scholar]
  8. Brumfitt W., Percival A. Antibiotic combinations. Lancet. 1971 Feb 20;1(7695):387–389. doi: 10.1016/s0140-6736(71)92223-9. [DOI] [PubMed] [Google Scholar]
  9. Bulger R. J., Feigl P., Nielson K. Comparison of treatments with several antibiotics in experimental infections due to methicillin-resistant Staphylococcus aureus. J Infect Dis. 1972 Dec;126(6):674–678. doi: 10.1093/infdis/126.6.674. [DOI] [PubMed] [Google Scholar]
  10. Bulger R. J. In vitro effectiveness of kanamycin and kanamycin/cephalothin against Klebsiella. Comparison with other antibiotics. Ann Intern Med. 1967 Sep;67(3):523–532. doi: 10.7326/0003-4819-67-3-523. [DOI] [PubMed] [Google Scholar]
  11. Burns M. W. Significance of Pseudomonas aeruginosa in sputum. Br Med J. 1973 Aug 18;3(5876):382–383. doi: 10.1136/bmj.3.5876.382. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Bushby S. R. Sensitivity testing with trimethorpim-sulphamethoxazole. Med J Aust. 1973 Jun 30;1(2 Suppl):10–18. [PubMed] [Google Scholar]
  13. CHABBERT Y. A., PATTE J. C. Cellophane transfer: application to the study of activity of combinations of antibiotics. Appl Microbiol. 1960 Jul;8:193–199. doi: 10.1128/am.8.4.193-199.1960. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Calabi O. Bactericidal synergism of novobiocin and tetracycline against Pseudomonas pseudomallei. J Med Microbiol. 1973 Aug;6(3):293–306. doi: 10.1099/00222615-6-3-293. [DOI] [PubMed] [Google Scholar]
  15. Charles B. G., Rawal B. D. Synergistic effect of methyl-substituted xanthines and neomycin sulphate on Staphylococcus aureus and Pseudomonas aeruginosa in vitro. Lancet. 1973 May 5;1(7810):971–973. doi: 10.1016/s0140-6736(73)91604-8. [DOI] [PubMed] [Google Scholar]
  16. Corrigan J. J., Jr, Sieber O. E., Jr, Ratajczak H., Bennett B. B. Modification of human neutrophil response to endotoxin with polymyxin B sulfate. J Infect Dis. 1974 Oct;130(4):384–387. doi: 10.1093/infdis/130.4.384. [DOI] [PubMed] [Google Scholar]
  17. DOWLING H. F., LEPPER M. H., JACKSON G. G. Observations on the epidemiological spread of antibiotic-resistant staphylococci, with measurements of the changes in sensitivity to penicillin and aureomycin. Am J Public Health Nations Health. 1953 Jul;43(7):860–868. doi: 10.2105/ajph.43.7.860. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. DOWLING H. F., LEPPER M. H., JACKSON G. G. When should antibiotics be used in combination? J Am Med Assoc. 1953 Mar 7;151(10):813–815. doi: 10.1001/jama.1953.02940100031009. [DOI] [PubMed] [Google Scholar]
  19. Dalton A. C., Plaut M. E. Susceptibility of Pseudomonas aeruginosa to colistin combined with carbenicillin or sulfamethoxazole. Am J Med Sci. 1971 Jun;261(6):335–340. doi: 10.1097/00000441-197106000-00004. [DOI] [PubMed] [Google Scholar]
  20. Davis S. D., Iannetta A., Wedgwood R. J. Paradoxical synergism and antagonism between serum and the antibacterial activity of colistin. J Infect Dis. 1971 Apr;123(4):392–398. doi: 10.1093/infdis/123.4.392. [DOI] [PubMed] [Google Scholar]
  21. De Ritis F., Giammanco G., Manzillo G. Chloramphenicol combined with ampicillin in treatment of typhoid. Br Med J. 1972 Oct 7;4(5831):17–18. doi: 10.1136/bmj.4.5831.17. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Dixon R. E., Goodman J. S., Koenig M. G. Lysostaphin: an enzymatic approach to staphylococcal disease. 3. Combined lysostaphin-methicillin therapy of established staphylococcal abscesses in mice. Yale J Biol Med. 1968 Aug;41(1):62–68. [PMC free article] [PubMed] [Google Scholar]
  23. Dowling H. F. Present status of therapy with combinations of antibiotics. Am J Med. 1965 Nov;39(5):796–811. doi: 10.1016/0002-9343(65)90098-7. [DOI] [PubMed] [Google Scholar]
  24. Durack D. T., Petersdorf R. G. Chemotherapy of experimental streptococcal endocarditis. I. Comparison of commonly recommended prophylactic regimens. J Clin Invest. 1973 Mar;52(3):592–598. doi: 10.1172/JCI107220. [DOI] [PMC free article] [PubMed] [Google Scholar]
  25. EAGLE H., FLEISCHMAN R., MUSSELMAN A. D. The bactericidal action of penicillin in vivo: the participation of the host, and the slow recovery of the surviving organisms. Ann Intern Med. 1950 Sep;33(3):544–571. doi: 10.7326/0003-4819-33-3-544. [DOI] [PubMed] [Google Scholar]
  26. Eickhoff T. C., Bennett J. V., Hayes P. S., Feeley J. Pseudomonas pseudomallei: susceptibility to chemotherapeutic agents. J Infect Dis. 1970 Feb;121(2):95–102. doi: 10.1093/infdis/121.2.95. [DOI] [PubMed] [Google Scholar]
  27. Finland M., Bach M. C., Garner C., Gold O. Synergistic action of ampicillin and erythromycin against Nocardia asteroides: effect of time of incubation. Antimicrob Agents Chemother. 1974 Mar;5(3):344–353. doi: 10.1128/aac.5.3.344. [DOI] [PMC free article] [PubMed] [Google Scholar]
  28. Finland M., Kass E. H. Trimethoprim-sulfamethoxazole. Summary and comments on the conference. J Infect Dis. 1973 Nov;128(Suppl):792–816. doi: 10.1093/infdis/128.supplement_3.s792. [DOI] [PubMed] [Google Scholar]
  29. Fixed combinations of antimicrobial agents. N Engl J Med. 1969 May 22;280(21):1149–1154. doi: 10.1056/NEJM196905222802104. [DOI] [PubMed] [Google Scholar]
  30. Forsgren A., Gnarpe H. Tetracycline interference with the bactericidal effect of serum. Nat New Biol. 1973 Jul 18;244(133):82–83. doi: 10.1038/newbio244082a0. [DOI] [PubMed] [Google Scholar]
  31. Fraher M. A., Jawetz E. Combined action of beta-lactamase-resistant and beta-lactamase-susceptible penicillins on 20 strains of Pseudomonas aeruginosa. Antimicrob Agents Chemother (Bethesda) 1967;7:711–715. [PubMed] [Google Scholar]
  32. GERONIMUS L. H. Inoculum size and the apparent sensitivity of staphylococci to penicillins. N Engl J Med. 1960 Aug 18;263:349–351. doi: 10.1056/NEJM196008182630706. [DOI] [PubMed] [Google Scholar]
  33. Garrett E. R., Won C. M. Effect of novobiocin and its combination with tetracycline, chloramphenicol, erythromycin, and lincomycin on the microbial generation of Escherichia coli. Antimicrob Agents Chemother. 1973 Dec;4(6):626–633. doi: 10.1128/aac.4.6.626. [DOI] [PMC free article] [PubMed] [Google Scholar]
  34. Greenfield S., Feingold D. S. The synergistic action of the sulfonamides and the polymyxins against Serratia marcescens. J Infect Dis. 1970 May;121(5):555–558. doi: 10.1093/infdis/121.5.555. [DOI] [PubMed] [Google Scholar]
  35. Grunberg E., Prince H. N., De Lorenzo W. F. The in vivo effect of folinic acid (citrovorum factor) on the potentiation of the antibacterial activity of sulfisoxazole by trimethoprim. J Clin Pharmacol J New Drugs. 1970 Jul-Aug;10(4):231–234. [PubMed] [Google Scholar]
  36. HERRELL W. E., BARBER T. E. A new method for treatment of brucellosis. J Am Med Assoc. 1950 Oct 14;144(7):519–524. doi: 10.1001/jama.1950.02920070007003. [DOI] [PubMed] [Google Scholar]
  37. Hamilton J., Burch W., Grimmett G., Orme K., Brewer D., Frost R., Fulkerson C. Successful treatment of Pseudomonas cepacia endocarditis with trimethoprim-sulfamethoxazole. Antimicrob Agents Chemother. 1973 Nov;4(5):551–554. doi: 10.1128/aac.4.5.551. [DOI] [PMC free article] [PubMed] [Google Scholar]
  38. Hoeprich P. D., Brandt D., Parker R. H. Nocardial brain abscess cured with cycloserine and sulfonamides. Am J Med Sci. 1968 Mar;255:208–216. doi: 10.1097/00000441-196803000-00008. [DOI] [PubMed] [Google Scholar]
  39. Huppert M., Sun S. H., Vukovich K. R. Combined amphotericin B-tetracycline therapy for experimental coccidioidomycosis. Antimicrob Agents Chemother. 1974 May;5(5):473–478. doi: 10.1128/aac.5.5.473. [DOI] [PMC free article] [PubMed] [Google Scholar]
  40. JONES W. F., Jr, FINLAND M. Antibiotic combinations: antibacterial action of plasma of normal subjects after oral doses of penicillin V, tetracycline hydrochloride and a combination of both. N Engl J Med. 1957 May 9;256(19):869–875. doi: 10.1056/NEJM195705092561901. [DOI] [PubMed] [Google Scholar]
  41. Jawetz E. The pharmacologic basis for the use of combinations of antimicrobial drugs. Pharmacol Physicians. 1967 Jan;1(1):1–6. [PubMed] [Google Scholar]
  42. Jensen K., Lassen H. C. Combined treatment with antibacterial chemotherapeutical agents in staphylococcal infections. Q J Med. 1969 Jan;38(149):91–106. [PubMed] [Google Scholar]
  43. Kabins S. A. Interactions among antibiotics and other drugs. JAMA. 1972 Jan 10;219(2):206–212. [PubMed] [Google Scholar]
  44. Kaplan K., Weinstein L. Diphtheroid infections of man. Ann Intern Med. 1969 May;70(5):919–929. doi: 10.7326/0003-4819-70-5-919. [DOI] [PubMed] [Google Scholar]
  45. Kasik J. E., Weber M., Winberg E., Barclay W. R. The synergistic effect of dicloxacillin and penicillin G on murine tuberculosis. Am Rev Respir Dis. 1966 Aug;94(2):260–261. doi: 10.1164/arrd.1966.94.2.260. [DOI] [PubMed] [Google Scholar]
  46. Kirkpatrick C. H., Smith T. K. Chronic mucocutaneous candidiasis: immunologic and antibiotic therapy. Ann Intern Med. 1974 Mar;80(3):310–320. doi: 10.7326/0003-4819-80-3-310. [DOI] [PubMed] [Google Scholar]
  47. Klastersky J., Cappel R., Daneau D. Clinical significance of in vitro synergism between antibiotics in gram-negative infections. Antimicrob Agents Chemother. 1972 Dec;2(6):470–475. doi: 10.1128/aac.2.6.470. [DOI] [PMC free article] [PubMed] [Google Scholar]
  48. Klastersky J., Cappel R., Debusscher L. Evaluation of gentamicin with carbenicillin in infections due to gram-negative bacilli. Curr Ther Res Clin Exp. 1971 Mar;13(3):174–181. [PubMed] [Google Scholar]
  49. Klastersky J., Henri A., Hensgens C., Daneau D. Gram-negative infections in cancer. Study of empiric therapy comparing carbenicillin-cephalothin with and without gentamicin. JAMA. 1974 Jan 7;227(1):45–48. doi: 10.1001/jama.227.1.45. [DOI] [PubMed] [Google Scholar]
  50. Klastersky J., Henri A., Vandenborre L. Antimicrobial activity of tobramycin and gentamicin used in combination with cephalothin and carbenicillin. Am J Med Sci. 1973 Jul;266(1):13–21. doi: 10.1097/00000441-197307000-00002. [DOI] [PubMed] [Google Scholar]
  51. Klastersky J., Swings G., Daneau D. Antimicrobial activity of the carbenicillin-gentamicin combination against gram-negative bacilli. Am J Med Sci. 1970 Dec;260(6):373–380. doi: 10.1097/00000441-197012000-00006. [DOI] [PubMed] [Google Scholar]
  52. Kleven S. H., Anderson D. P. In vitro activity of various antibiotics against Mycoplasma synoviae. Avian Dis. 1971 Jul-Sep;15(3):551–557. [PubMed] [Google Scholar]
  53. Kluge R. M., Standiford H. C., Tatem B., Young V. M., Schimpff S. C., Greene W. H., Calia F. M., Hornick R. B. The carbenicillin-gentamicin combination against Pseudomonas aeruginosa. Correlation of effect with gentamicin sensitivity. Ann Intern Med. 1974 Nov;81(5):584–587. doi: 10.7326/0003-4819-81-5-584. [DOI] [PubMed] [Google Scholar]
  54. Kobbayashi G. S., Medoff G., Schlessinger D., Kwan C. N., Musser W. E. Amphotericin B potentiation of rifampicin as an antifungal agent against the yeast phase of Histoplasma capsulatum. Science. 1972 Aug 25;177(4050):709–710. doi: 10.1126/science.177.4050.709. [DOI] [PubMed] [Google Scholar]
  55. LACEY B. W. The rationale and management of combined therapy. Br Med Bull. 1960 Jan;16:42–46. doi: 10.1093/oxfordjournals.bmb.a069790. [DOI] [PubMed] [Google Scholar]
  56. LEPPER M. H., DOWLING H. F. Treatment of pneumococcic meningitis with penicillin compared with penicillin plus aureomycin; studies including observations on an apparent antagonism between penicillin and aureomycin. AMA Arch Intern Med. 1951 Oct;88(4):489–494. doi: 10.1001/archinte.1951.03810100073006. [DOI] [PubMed] [Google Scholar]
  57. LEPPER M. H. Recent developments in antibiotic treatment. Wis Med J. 1958 May;57(5):207–214. [PubMed] [Google Scholar]
  58. LOURIA D. B., KAMINSKI T. The effects of four antimicrobial drug regimens on sputum superinfection in hospitalized patients. Am Rev Respir Dis. 1962 May;85:649–665. doi: 10.1164/arrd.1962.85.5.649. [DOI] [PubMed] [Google Scholar]
  59. MAGILL G. B., KILLOUGH J. H. Oxytetracycline-streptomycin therapy in brucellosis due to Brucella melitensis. AMA Arch Intern Med. 1953 Feb;91(2):204–211. doi: 10.1001/archinte.1953.00240140064005. [DOI] [PubMed] [Google Scholar]
  60. Mandell G. L., Vest T. K. Killing of intraleukocytic Staphylococcus aureus by rifampin: in-vitro and in-vivo studies. J Infect Dis. 1972 May;125(5):486–490. doi: 10.1093/infdis/125.5.486. [DOI] [PubMed] [Google Scholar]
  61. Martin C. M., Cuomo A. J., Geraghty M. J., Zager J. R., Mandes T. C. Gram-negative rod bacteremia. J Infect Dis. 1969 Apr-May;119(4):506–517. doi: 10.1093/infdis/119.4-5.506. [DOI] [PubMed] [Google Scholar]
  62. McLaughlin J. E., Reeves D. S. Clinical and laboratory evidence for inactivation of gentamicin by carbenicillin. Lancet. 1971 Feb 6;1(7693):261–264. doi: 10.1016/s0140-6736(71)91001-4. [DOI] [PubMed] [Google Scholar]
  63. Medoff G., Comfort M., Kobayashi G. S. Synergistic action of amphotericin B and 5-fluorocytosine against yeast-like organisms. Proc Soc Exp Biol Med. 1971 Nov;138(2):571–574. doi: 10.3181/00379727-138-35943. [DOI] [PubMed] [Google Scholar]
  64. Meers P. D. Bacteroides infections. Lancet. 1973 Sep 8;2(7828):573–573. doi: 10.1016/s0140-6736(73)92399-4. [DOI] [PubMed] [Google Scholar]
  65. Michel J., Luboshitzky R., Sacks T. Bactericidal effect of combinations of nalidixic acid and various antibiotics on Enterobacteriaceae. Antimicrob Agents Chemother. 1973 Sep;4(3):201–204. doi: 10.1128/aac.4.3.201. [DOI] [PMC free article] [PubMed] [Google Scholar]
  66. Moellering R. C., Jr, Medoff G., Leech I., Wennersten C., Kunz L. J. Antibiotic synergism against Listeria monocytogenes. Antimicrob Agents Chemother. 1972 Jan;1(1):30–34. doi: 10.1128/aac.1.1.30. [DOI] [PMC free article] [PubMed] [Google Scholar]
  67. Moellering R. C., Jr Use and abuse of antibiotic combinations. R I Med J. 1972 Nov;55(11):341–passim. [PubMed] [Google Scholar]
  68. Moellering R. C., Jr, Wennersten C., Weinstein A. J. Penicillin-tobramycin synergism against enterococci: a comparison with penicillin and gentamicin. Antimicrob Agents Chemother. 1973 Apr;3(4):526–529. doi: 10.1128/aac.3.4.526. [DOI] [PMC free article] [PubMed] [Google Scholar]
  69. Mouton R. P., Koelman A. The interaction patterns of combined antibacterial agents. Experiments with two agardiffusion methods. Chemotherapy. 1966;11(1):10–26. doi: 10.1159/000220434. [DOI] [PubMed] [Google Scholar]
  70. Nelson J. D., McCracken G. H., Jr Clinical pharmacology of carbenicillin and gentamicin in the neonate and comparative efficacy with ampicillin and gentamicin. Pediatrics. 1973 Dec;52(6):801–812. [PubMed] [Google Scholar]
  71. Nord C. E., Wadström T., Wretlind B. Synergistic effect of combinations of sulfamethoxazole, trimethoprim, and colistin against Pseudomonas maltophilia and Pseudomonas cepacia. Antimicrob Agents Chemother. 1974 Oct;6(4):521–523. doi: 10.1128/aac.6.4.521. [DOI] [PMC free article] [PubMed] [Google Scholar]
  72. O'Grady F., Greenwood D. Interactions between fusidic acid and penicillins. J Med Microbiol. 1973 Nov;6(4):441–450. doi: 10.1099/00222615-6-4-441. [DOI] [PubMed] [Google Scholar]
  73. OLSSON R. A., KIRBY J. C., ROMANSKY M. J. Pneumococcal meningitis in the adult. Clinical, therapeutic, and prognostic aspects in forty-three patients. Ann Intern Med. 1961 Oct;55:545–549. doi: 10.7326/0003-4819-55-4-545. [DOI] [PubMed] [Google Scholar]
  74. PRYLES C. V. Current status of combined antibiotic therapy. Pediatrics. 1958 Jun;21(6):1000–1009. [PubMed] [Google Scholar]
  75. Piguet J. D. Láction inhibitrice de la nitrofurantoïne sur le pouvoir bactériostatique in vitro de lácide nalidixique. Ann Inst Pasteur (Paris) 1969 Jan;116(1):43–48. [PubMed] [Google Scholar]
  76. Prescott L. F. Clinically important drug interactions. Drugs. 1973;5(3):161–186. doi: 10.2165/00003495-197305030-00001. [DOI] [PubMed] [Google Scholar]
  77. RUSSELL F. E. SYNERGISM BETWEEN SULPHONAMIDE DRUGS AND ANTIBIOTICS OF THE POLYMYXIN GROUP AGAINST PROTEUS SP. IN VITRO. J Clin Pathol. 1963 Jul;16:362–366. doi: 10.1136/jcp.16.4.362. [DOI] [PMC free article] [PubMed] [Google Scholar]
  78. Rahal J. J., Jr, Simberkoff M. S., Hyams P. J. Pseudomonas cepacia tricuspid endocarditis: treatment with trimethoprim, sulfonamide, and polymyxin B. J Infect Dis. 1973 Nov;128(Suppl):762–p. doi: 10.1093/infdis/128.supplement_3.s762. [DOI] [PubMed] [Google Scholar]
  79. Rawal B. D., McKay G., Blackhall M. I. Inhibition of Pseudomonas aeruginosa by ascorbic acid acting singly and in combination with antimicrobials: in-vitro and in-vivo studies. Med J Aust. 1974 Feb 9;1(6):169–174. doi: 10.5694/j.1326-5377.1974.tb50784.x. [DOI] [PubMed] [Google Scholar]
  80. Riley H. D., Jr Drug interactions. IV. Interactions among antimicrobial and nonantimicrobial agents. Pediatrics. 1972 Dec;50(6):954–955. [PubMed] [Google Scholar]
  81. Rosenblatt J. E., Stewart P. R. Combined activity of sulfamethoxazole, trimethoprim, and polymyxin B against gram-negative bacilli. Antimicrob Agents Chemother. 1974 Jul;6(1):84–92. doi: 10.1128/aac.6.1.84. [DOI] [PMC free article] [PubMed] [Google Scholar]
  82. Ruhen R. W., Darrell J. H. Antibiotic synergism against group D streptococci in the treatment of endocarditis. Med J Aust. 1973 Jul 21;2(3):114–116. doi: 10.5694/j.1326-5377.1973.tb128693.x. [DOI] [PubMed] [Google Scholar]
  83. STROM J. The question of antagonism between penicillin and chlortetracycline, illustrated by therapeutical experiments in scarlatina. Antibiotic Med Clin Ther (New York) 1955 Jan;1(1):6–12. [PubMed] [Google Scholar]
  84. Sabath L. D., Elder H. A., McCall C. E., Finland M. Synergistic combinations of penicillins in the treatment of bacteriuria. N Engl J Med. 1967 Aug 3;277(5):232–238. doi: 10.1056/NEJM196708032770503. [DOI] [PubMed] [Google Scholar]
  85. Sande M. A., Irvin R. G. Penicillin-aminoglycoside synergy in experimental Streptococcus viridans endocarditis. J Infect Dis. 1974 May;129(5):572–576. doi: 10.1093/infdis/129.5.572. [DOI] [PubMed] [Google Scholar]
  86. Sande M. A., Overton J. W. In vivo antagonism between gentamicin and chloramphenicol in neutropenic mice. J Infect Dis. 1973 Aug;128(2):247–250. doi: 10.1093/infdis/128.2.247. [DOI] [PubMed] [Google Scholar]
  87. Schofield C. B., Masterton G., Moffett M., McGill M. I. Gonorrhea in women: treatment with sulfamethoxazole and trimethoprim. J Infect Dis. 1971 Dec;124(6):533–538. doi: 10.1093/infdis/124.6.533. [DOI] [PubMed] [Google Scholar]
  88. Simmons H. E., Stolley P. D. This is medical progress? Trends and consequences of antibiotic use in the United States. JAMA. 1974 Mar 4;227(9):1023–1028. doi: 10.1001/jama.227.9.1023. [DOI] [PubMed] [Google Scholar]
  89. Speller D. C. Pseudomonas cepacia endocarditis treated with co-trimoxazole and kanamycin. Br Heart J. 1973 Jan;35(1):47–48. doi: 10.1136/hrt.35.1.47. [DOI] [PMC free article] [PubMed] [Google Scholar]
  90. Standiford H. D., De Maine J. B., Kirby W. M. Antibiotic synergism of enterococci. Relation to inhibitory concentrations. Arch Intern Med. 1970 Aug;126(2):255–259. [PubMed] [Google Scholar]
  91. TAYLOR G., BLOOR K. Antistaphylococcal activity of fucidin. Lancet. 1962 May 5;1(7236):935–937. doi: 10.1016/s0140-6736(62)91972-4. [DOI] [PubMed] [Google Scholar]
  92. TOMPSETT R. Antimicrobial therapy: the concurrent administration of two drugs. Am J Med Sci. 1958 May;235(5):585–595. [PubMed] [Google Scholar]
  93. Tattersall M. H., Spiers A. S., Darrell J. H. Initial therapy with combination of five antibiotics in febrile patients with leukaemia and neutropenia. Lancet. 1972 Jan 22;1(7743):162–165. doi: 10.1016/s0140-6736(72)90567-3. [DOI] [PubMed] [Google Scholar]
  94. Then R., Angehrn P. Nature of the bacterial action of sulfonamides and trimethoprim, alone and in combination. J Infect Dis. 1973 Nov;128(Suppl):498–501. doi: 10.1093/infdis/128.supplement_3.s498. [DOI] [PubMed] [Google Scholar]
  95. WATERWORTH P. M. Apparent synergy between penicillin and erythromycin or fusidic acid. Clin Med (Northfield) 1963 May;70:941–953. [PubMed] [Google Scholar]
  96. WEINSTEIN L. The use and misuse of antibiotic combinations. J Maine Med Assoc. 1958 Oct;49(10):365–371. [PubMed] [Google Scholar]
  97. Waitz J. A., Drube C. G., Moss E. L., Jr, Oden E. M., Bailey J. V. Biological aspects of the interaction between gentamicin and carbenicillin. J Antibiot (Tokyo) 1972 Apr;25(4):219–225. doi: 10.7164/antibiotics.25.219. [DOI] [PubMed] [Google Scholar]
  98. Wallace J. F., Smith R. H., Garcia M., Petersdorf R. G. Studies on the pathogenesis of meningitis. VI. Antagonism between penicillin and chloramphenicol in experimental pneumococcal meningitis. J Lab Clin Med. 1967 Sep;70(3):408–418. [PubMed] [Google Scholar]
  99. Weidmer C. E., Dunkel T. B., Pettyjohn F. S., Smith C. D., Leibovitz A. Effectiveness of rifampin in eradicating the meningococcal carrier state in a relatively closed population: emergence of resistant strains. J Infect Dis. 1971 Aug;124(2):172–178. doi: 10.1093/infdis/124.2.172. [DOI] [PubMed] [Google Scholar]
  100. Williams B. J. Factors which influence synergism by neomycin and oxytetracycline. Appl Microbiol. 1971 Apr;21(4):668–672. doi: 10.1128/am.21.4.668-672.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]
  101. Wright G. L., Harper J. Fusidic acid and lincomycin therapy in staphylococcal infections in cystic fibrosis. Lancet. 1970 Jan 3;1(7636):9–14. doi: 10.1016/s0140-6736(70)90523-4. [DOI] [PubMed] [Google Scholar]
  102. Ziment I. Complications of antibiotic therapy. Calif Med. 1972 Nov;117(5):24–48. [PMC free article] [PubMed] [Google Scholar]

Articles from Bulletin of the New York Academy of Medicine are provided here courtesy of New York Academy of Medicine

RESOURCES