Skip to main content
Journal of Epidemiology and Community Health logoLink to Journal of Epidemiology and Community Health
. 2005 Jul;59(7):598–602. doi: 10.1136/jech.2004.025288

Effect of psychiatric illness and labour market status on suicide: a healthy worker effect?

E Agerbo 1
PMCID: PMC1757077  PMID: 15965145

Abstract

Study objective: To describe the association between labour market status and death by suicide with focus on admission with a psychiatric disorder.

Design: Nested case-control study. Data from routine registers.

Setting: Entire Danish population.

Participants: 9011 people aged 25–60 years who committed suicide during 1982–1997 and 180 220 matched controls.

Main results: In the general population, not being fully employed is associated with a twofold to threefold increased relative risk of death by suicide, compared with being fully employed. In contrast, fully employed people who have been first admitted to a psychiatric hospital within the past year are at increased suicide risk. Patients who are unemployed, social benefits recipients, disability pensioners, or otherwise marginalised on the labour market have a suicide risk of 0.60 (95% CI: 0.46 to 0.78), 0.41 (0.23 to 0.74), 0.70 (0.45 to 1.08), and 0.86 (0.53 to 1.41), respectively. Although a similar risk decrease is found in women, men, people younger than 30 years, people older than 45 years, and in people who become unemployed, the reversed effect attenuates with time since admission, and little association is seen when a marginal structural model is applied.

Conclusions: Although the results show an increased suicide mortality associated with unemployment and labour market marginalisation in the general population, the results suggest little or an inverse association between unemployment and suicide in people with psychiatric illness. The associations seen suggest the need to consider healthy worker selection effects when studying the causal pathway from unemployment and psychiatric illness to suicide.

Full Text

The Full Text of this article is available as a PDF (75.9 KB).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Agerbo E., Mortensen P. B., Eriksson T., Qin P., Westergaard-Nielsen N. Risk of suicide in relation to income level in people admitted to hospital with mental illness: nested case-control study. BMJ. 2001 Feb 10;322(7282):334–335. doi: 10.1136/bmj.322.7282.334. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Agerbo E. Unemployment and suicide. J Epidemiol Community Health. 2003 Aug;57(8):560–561. doi: 10.1136/jech.57.8.560. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Agerbo Esben, Byrne Majella, Eaton William W., Mortensen Preben B. Marital and labor market status in the long run in schizophrenia. Arch Gen Psychiatry. 2004 Jan;61(1):28–33. doi: 10.1001/archpsyc.61.1.28. [DOI] [PubMed] [Google Scholar]
  4. Agerbo Esben. Midlife suicide risk, partner's psychiatric illness, spouse and child bereavement by suicide or other modes of death: a gender specific study. J Epidemiol Community Health. 2005 May;59(5):407–412. doi: 10.1136/jech.2004.024950. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Agerbo Esben, Nordentoft Merete, Mortensen Preben Bo. Familial, psychiatric, and socioeconomic risk factors for suicide in young people: nested case-control study. BMJ. 2002 Jul 13;325(7355):74–74. doi: 10.1136/bmj.325.7355.74. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Appleby L., Dennehy J. A., Thomas C. S., Faragher E. B., Lewis G. Aftercare and clinical characteristics of people with mental illness who commit suicide: a case-control study. Lancet. 1999 Apr 24;353(9162):1397–1400. doi: 10.1016/S0140-6736(98)10014-4. [DOI] [PubMed] [Google Scholar]
  7. Barraclough B., Bunch J., Nelson B., Sainsbury P. A hundred cases of suicide: clinical aspects. Br J Psychiatry. 1974 Oct;125(0):355–373. doi: 10.1192/bjp.125.4.355. [DOI] [PubMed] [Google Scholar]
  8. Beautrais A. L., Joyce P. R., Mulder R. T. Unemployment and serious suicide attempts. Psychol Med. 1998 Jan;28(1):209–218. doi: 10.1017/s0033291797005990. [DOI] [PubMed] [Google Scholar]
  9. Blakely T. A., Collings S. C. D., Atkinson J. Unemployment and suicide. Evidence for a causal association? J Epidemiol Community Health. 2003 Aug;57(8):594–600. doi: 10.1136/jech.57.8.594. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Bodnar Lisa M., Davidian Marie, Siega-Riz Anna Maria, Tsiatis Anastasios A. Marginal structural models for analyzing causal effects of time-dependent treatments: an application in perinatal epidemiology. Am J Epidemiol. 2004 May 15;159(10):926–934. doi: 10.1093/aje/kwh131. [DOI] [PubMed] [Google Scholar]
  11. Borgan O., Langholz B. Nonparametric estimation of relative mortality from nested case-control studies. Biometrics. 1993 Jun;49(2):593–602. [PubMed] [Google Scholar]
  12. Ezzy D. Unemployment and mental health: a critical review. Soc Sci Med. 1993 Jul;37(1):41–52. doi: 10.1016/0277-9536(93)90316-v. [DOI] [PubMed] [Google Scholar]
  13. Fergusson D. M., Horwood L. J., Woodward L. J. Unemployment and psychosocial adjustment in young adults: causation or selection? Soc Sci Med. 2001 Aug;53(3):305–320. doi: 10.1016/s0277-9536(00)00344-0. [DOI] [PubMed] [Google Scholar]
  14. Gunnell D., Lopatatzidis A., Dorling D., Wehner H., Southall H., Frankel S. Suicide and unemployment in young people. Analysis of trends in England and Wales, 1921-1995. Br J Psychiatry. 1999 Sep;175:263–270. doi: 10.1192/bjp.175.3.263. [DOI] [PubMed] [Google Scholar]
  15. Hernán M. A., Brumback B., Robins J. M. Marginal structural models to estimate the causal effect of zidovudine on the survival of HIV-positive men. Epidemiology. 2000 Sep;11(5):561–570. doi: 10.1097/00001648-200009000-00012. [DOI] [PubMed] [Google Scholar]
  16. Hernán Miguel A., Brumback Babette A., Robins James M. Estimating the causal effect of zidovudine on CD4 count with a marginal structural model for repeated measures. Stat Med. 2002 Jun 30;21(12):1689–1709. doi: 10.1002/sim.1144. [DOI] [PubMed] [Google Scholar]
  17. Iversen L., Andersen O., Andersen P. K., Christoffersen K., Keiding N. Unemployment and mortality in Denmark, 1970-80. Br Med J (Clin Res Ed) 1987 Oct 10;295(6603):879–884. doi: 10.1136/bmj.295.6603.879. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Kessler R. C., Foster C. L., Saunders W. B., Stang P. E. Social consequences of psychiatric disorders, I: Educational attainment. Am J Psychiatry. 1995 Jul;152(7):1026–1032. doi: 10.1176/ajp.152.7.1026. [DOI] [PubMed] [Google Scholar]
  19. King Gary, Zeng Langche. Estimating risk and rate levels, ratios and differences in case-control studies. Stat Med. 2002 May 30;21(10):1409–1427. doi: 10.1002/sim.1032. [DOI] [PubMed] [Google Scholar]
  20. Kposowa A. J. Research on unemployment and suicide. J Epidemiol Community Health. 2003 Aug;57(8):559–560. doi: 10.1136/jech.57.8.559. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. Kposowa A. J. Unemployment and suicide: a cohort analysis of social factors predicting suicide in the US National Longitudinal Mortality Study. Psychol Med. 2001 Jan;31(1):127–138. doi: 10.1017/s0033291799002925. [DOI] [PubMed] [Google Scholar]
  22. Lester D., Yang B. Unemployment and suicidal behaviour. J Epidemiol Community Health. 2003 Aug;57(8):558–559. doi: 10.1136/jech.57.8.558. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. Lewis G., Sloggett A. Suicide, deprivation, and unemployment: record linkage study. BMJ. 1998 Nov 7;317(7168):1283–1286. doi: 10.1136/bmj.317.7168.1283. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. Li C. Y., Sung F. C. A review of the healthy worker effect in occupational epidemiology. Occup Med (Lond) 1999 May;49(4):225–229. doi: 10.1093/occmed/49.4.225. [DOI] [PubMed] [Google Scholar]
  25. Martikainen P. T., Valkonen T. The effects of differential unemployment rate increases of occupation groups on changes in mortality. Am J Public Health. 1998 Dec;88(12):1859–1861. doi: 10.2105/ajph.88.12.1859. [DOI] [PMC free article] [PubMed] [Google Scholar]
  26. Mortensen P. B., Agerbo E., Erikson T., Qin P., Westergaard-Nielsen N. Psychiatric illness and risk factors for suicide in Denmark. Lancet. 2000 Jan 1;355(9197):9–12. doi: 10.1016/s0140-6736(99)06376-x. [DOI] [PubMed] [Google Scholar]
  27. Munk-Jørgensen P., Mortensen P. B. The Danish Psychiatric Central Register. Dan Med Bull. 1997 Feb;44(1):82–84. [PubMed] [Google Scholar]
  28. Mäkinen I. H. Effect on suicide rate of having reduced unemployment is uncertain. BMJ. 1999 Apr 3;318(7188):941–942. [PMC free article] [PubMed] [Google Scholar]
  29. Neumayer Eric. Recessions lower (some) mortality rates: evidence from Germany. Soc Sci Med. 2004 Mar;58(6):1037–1047. doi: 10.1016/s0277-9536(03)00276-4. [DOI] [PubMed] [Google Scholar]
  30. Powell J., Geddes J., Deeks J., Goldacre M., Hawton K. Suicide in psychiatric hospital in-patients. Risk factors and their predictive power. Br J Psychiatry. 2000 Mar;176:266–272. doi: 10.1192/bjp.176.3.266. [DOI] [PubMed] [Google Scholar]
  31. Qin Ping, Agerbo Esben, Mortensen Preben Bo. Suicide risk in relation to socioeconomic, demographic, psychiatric, and familial factors: a national register-based study of all suicides in Denmark, 1981-1997. Am J Psychiatry. 2003 Apr;160(4):765–772. doi: 10.1176/appi.ajp.160.4.765. [DOI] [PubMed] [Google Scholar]
  32. Robins J. M., Hernán M. A., Brumback B. Marginal structural models and causal inference in epidemiology. Epidemiology. 2000 Sep;11(5):550–560. doi: 10.1097/00001648-200009000-00011. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Epidemiology and Community Health are provided here courtesy of BMJ Publishing Group

RESOURCES