Skip to main content
PMC home page
Antimicrobial Agents and Chemotherapy logoLink to Antimicrobial Agents and Chemotherapy
. 1988 Sep;32(9):1430–1432. doi: 10.1128/aac.32.9.1430

Transfer of beta-lactamase plasmids from Neisseria gonorrhoeae to Neisseria meningitidis and commensal Neisseria species by the 25.2-megadalton conjugative plasmid.

M C Roberts 1, J S Knapp 1
PMCID: PMC175882  PMID: 3143304

Abstract

Two highly tetracycline-resistant, beta-lactamase-producing Neisseria gonorrhoeae strains were used as donors for conjugation with Neisseria meningitidis and commensal Neisseria species. We found that both strains were able to transfer the 4.4- and 3.2-megadalton beta-lactamase plasmids to the recipients tested, with frequencies between 10(-1) and 10(-9).

Full text

PDF
1431

Images in this article

1431Image
on p.1431

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Anderson B., Albritton W. L., Biddle J., Johnson S. R. Common beta-lactamase-specifying plasmid in Haemophilus ducreyi and Neisseria gonorrhoeae. Antimicrob Agents Chemother. 1984 Feb;25(2):296–297. doi: 10.1128/aac.25.2.296. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Brown J. T., Roberts M. C. Cloning and characterization of tetM gene from a Ureaplasma urealyticum strain. Antimicrob Agents Chemother. 1987 Nov;31(11):1852–1854. doi: 10.1128/aac.31.11.1852. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Burdett V., Inamine J., Rajagopalan S. Heterogeneity of tetracycline resistance determinants in Streptococcus. J Bacteriol. 1982 Mar;149(3):995–1004. doi: 10.1128/jb.149.3.995-1004.1982. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Dillon J. R., Pauzé M., Yeung K. H. Spread of penicillinase-producing and transfer plasmids from the gonococcus to Neisseria meningitidis. Lancet. 1983 Apr 9;1(8328):779–781. doi: 10.1016/s0140-6736(83)91846-9. [DOI] [PubMed] [Google Scholar]
  5. Facinelli B., Montanari M. P., Piermattei P. Plasmid deoxyribonucleic acid in throat and cerebrospinal fluid isolates of Neisseria meningitidis. Eur J Epidemiol. 1987 Jun;3(2):206–208. doi: 10.1007/BF00239761. [DOI] [PubMed] [Google Scholar]
  6. Facinelli B., Varaldo P. E. Plasmid-mediated sulfonamide resistance in Neisseria meningitidis. Antimicrob Agents Chemother. 1987 Oct;31(10):1642–1643. doi: 10.1128/aac.31.10.1642. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Genco C. A., Knapp J. S., Clark V. L. Conjugation of plasmids of Neisseria gonorrhoeae to other Neisseria species: potential reservoirs for the beta-lactamase plasmid. J Infect Dis. 1984 Sep;150(3):397–401. doi: 10.1093/infdis/150.3.397. [DOI] [PubMed] [Google Scholar]
  8. Guiney D. G., Jr, Ito J. I., Jr Transfer of the gonococcal penicillinase plasmid: mobilization in Escherichia coli by IncP plasmids and isolation as a DNA-protein relaxation complex. J Bacteriol. 1982 Apr;150(1):298–302. doi: 10.1128/jb.150.1.298-302.1982. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Ikeda F., Tsuji A., Kaneko Y., Nishida M., Goto S. Conjugal transfer of beta-lactamase-producing plasmids of Neisseria gonorrhoeae to Neisseria meningitidis. Microbiol Immunol. 1986;30(8):737–742. doi: 10.1111/j.1348-0421.1986.tb03000.x. [DOI] [PubMed] [Google Scholar]
  10. Knapp J. S., Johnson S. R., Zenilman J. M., Roberts M. C., Morse S. A. High-level tetracycline resistance resulting from TetM in strains of Neisseria spp., Kingella denitrificans, and Eikenella corrodens. Antimicrob Agents Chemother. 1988 May;32(5):765–767. doi: 10.1128/aac.32.5.765. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Knapp J. S., Zenilman J. M., Biddle J. W., Perkins G. H., DeWitt W. E., Thomas M. L., Johnson S. R., Morse S. A. Frequency and distribution in the United States of strains of Neisseria gonorrhoeae with plasmid-mediated, high-level resistance to tetracycline. J Infect Dis. 1987 Apr;155(4):819–822. doi: 10.1093/infdis/155.4.819. [DOI] [PubMed] [Google Scholar]
  12. Martel A. Y., Gosselin P., Ouellette M., Roy P. H., Bergeron M. G. Isolation and molecular characterization of beta-lactamase-producing Haemophilus parainfluenzae from the genital tract. Antimicrob Agents Chemother. 1987 Jun;31(6):966–968. doi: 10.1128/aac.31.6.966. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. McNicol P. J., Albritton W. L., Ronald A. R. Characterization of a Haemophilus ducreyi mobilizing plasmid. J Bacteriol. 1986 Feb;165(2):657–659. doi: 10.1128/jb.165.2.657-659.1986. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Morse S. A., Johnson S. R., Biddle J. W., Roberts M. C. High-level tetracycline resistance in Neisseria gonorrhoeae is result of acquisition of streptococcal tetM determinant. Antimicrob Agents Chemother. 1986 Nov;30(5):664–670. doi: 10.1128/aac.30.5.664. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Pintado C., Salvador C., Rotger R., Nombela C. Multiresistance plasmid from commensal Neisseria strains. Antimicrob Agents Chemother. 1985 Jan;27(1):120–124. doi: 10.1128/aac.27.1.120. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Prère M. F., Fayet O., Delmas C., Lareng M. B., Dabernat H. Présence de plasmides chez Neisseria meningitidis. Ann Inst Pasteur Microbiol. 1985 Mar-Apr;136A(2):271–276. doi: 10.1016/s0769-2609(85)80066-1. [DOI] [PubMed] [Google Scholar]
  17. Roberts M. C., Knapp J. S. Host range of the conjugative 25.2-megadalton tetracycline resistance plasmid from Neisseria gonorrhoeae and related species. Antimicrob Agents Chemother. 1988 Apr;32(4):488–491. doi: 10.1128/aac.32.4.488. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Roberts M., Falkow S. Conjugal transfer of R plasmids in Neisseria gonorrhoeae. Nature. 1977 Apr 14;266(5603):630–631. doi: 10.1038/266630a0. [DOI] [PubMed] [Google Scholar]
  19. Robledano L., Rivera M. J., Otal I., Gómez-Lus R. Enzymatic modification of aminoglycoside antibiotics by Branhamella catarrhalis carrying an R factor. Drugs Exp Clin Res. 1987;13(3):137–143. [PubMed] [Google Scholar]
  20. Rotger R., Rubio F., Nombela C. A multi-resistance plasmid isolated from commensal Neisseria species is closely related to the enterobacterial plasmid RSF1010. J Gen Microbiol. 1986 Sep;132(9):2491–2496. doi: 10.1099/00221287-132-9-2491. [DOI] [PubMed] [Google Scholar]
  21. Verschueren H., Dekegel M., Dekegel D., Gilquin C., de Mayer S. Plasmids in Neisseria meningitidis. Lancet. 1982 Apr 10;1(8276):851–852. doi: 10.1016/s0140-6736(82)91896-7. [DOI] [PubMed] [Google Scholar]

Articles from Antimicrobial Agents and Chemotherapy are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES