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. 1988 Nov;32(11):1619–1623. doi: 10.1128/aac.32.11.1619

Efficacies of four antifungal agents in experimental murine sporotrichosis.

V L Kan 1, J E Bennett 1
PMCID: PMC175939  PMID: 2855294

Abstract

Four antifungal agents, amphotericin B, SDZ 89-485, itraconazole, and terbinafine, were tested for efficacy in a murine model of systemic sporotrichosis. Survival in the groups treated with amphotericin B, SDZ 89-485, and itraconazole was significantly better than that of control infected mice. However, these agents did not wholly protect the infected mice, as tail and paw lesions, whole-body radiographs, and positive cultures from survivors showed evidence of dissemination. Terbinafine-treated mice had the same or poorer survival as control infected mice, despite documented drug absorption.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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