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. 1973 May;48(1):144–147. doi: 10.1111/j.1476-5381.1973.tb08232.x

Some observations on the β-adrenoceptor agonist properties of the isomers of salbutamol

R T Brittain, J B Farmer, R J Marshall
PMCID: PMC1776090  PMID: 4146763

Abstract

1. The pharmacological activities of the optical isomers of salbutamol have been examined. (-)-Salbutamol was much more potent than (+)-salbutamol on β-adrenoceptors.

2. Both (-)- and (+)-salbutamol showed high selectivity for β-adrenoceptors in bronchial muscle compared to cardiac muscle, in this way resembling racemic salbutamol.

3. The use of isomeric activity ratio to detect differences between receptors was examined in the light of the results obtained with the isomers of salbutamol.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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