Abstract
The content of cyclic 3',5'-adenosine monophosphate (cAMP) in the gills of the mullet (Mugil capito) has been measured. The basal level was found to be 2·9±0·3 pmol/mg wet weight. When fish were first anaesthetized with MS222 (tricaine) and the gills perfused to remove blood, the concentration of cAMP was raised to 14·3±1·9 pmol/mg wet weight.
Adrenaline caused a significant increase in cAMP content, an effect that was blocked by propranalol, a β-adrenoceptor antagonist. In the presence of the α-adrenoceptor block- ing agent phentolamine, adrenaline still caused an increase in nucleotide content.
The results are discussed in relation to adrenaline and the adenyl cyclase system.
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Selected References
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