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. 1985 Apr;60(4):326–332. doi: 10.1136/adc.60.4.326

Intestinal permeability changes and excretion of micro-organisms in stools of infants with diarrhoea and vomiting.

L T Weaver, P D Chapman, C R Madeley, M F Laker, R Nelson
PMCID: PMC1777215  PMID: 3923945

Abstract

The relation between diarrhoea and vomiting, the excretion of stool micro-organisms, and the passive intestinal permeability in 20 infants living in a deprived urban area was studied prospectively from birth to age 6 months. Intestinal permeability was measured from the ratio of lactulose to mannitol recovered in the urine of infants receiving feeds containing both markers. Micro-organism excretion was found to occur in both the presence and absence of gastrointestinal symptoms, but a significantly higher mean intestinal permeability was recorded in those infants with symptoms and organisms in the stool than in those with neither. An increased intestinal permeability may be a sign of mucosal damage by intestinal micro-organisms.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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