Skip to main content
Archives of Disease in Childhood logoLink to Archives of Disease in Childhood
. 1986 Jan;61(1):61–66. doi: 10.1136/adc.61.1.61

The nutritional cost of measles in Africa.

M B Duggan, J Alwar, R D Milner
PMCID: PMC1777543  PMID: 3954420

Abstract

A 24 hour energy balance study was carried out on 20 black Kenyan children with acute measles and repeated after recovery. The energy content of a weighed 24 hour food intake and of a simultaneous collection of faeces and urine was determined by bomb calorimetry. Energy expenditure was measured by indirect calorimetry using a purpose built flow over calorimeter. The nutritional state of the children was assessed by anthropometry at the time of each study and during convalescence. The results showed a fall of roughly 75% in the intake of gross and metabolisable energy during measles, while the resting energy expenditure was little affected. Thus the severe degree of negative apparent energy balance observed during measles is the combined effect of underfeeding in ill children, and failure, during starvation related to infection, of the early fall in metabolic rate that characterises simple underfeeding.

Full text

PDF
62

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Beisel W. R. Magnitude of the host nutritional responses to infection. Am J Clin Nutr. 1977 Aug;30(8):1236–1247. doi: 10.1093/ajcn/30.8.1236. [DOI] [PubMed] [Google Scholar]
  2. Bistrian B. R. Interaction of nutrition and infection in the hospital setting. Am J Clin Nutr. 1977 Aug;30(8):1228–1235. doi: 10.1093/ajcn/30.8.1228. [DOI] [PubMed] [Google Scholar]
  3. Brooke O. G., Alvear J., Arnold M. Energy retention, energy expenditure, and growth in healthy immature infants. Pediatr Res. 1979 Apr;13(4 Pt 1):215–220. doi: 10.1203/00006450-197904000-00001. [DOI] [PubMed] [Google Scholar]
  4. Cherian A., Duggan M. B., Sterken E. Anthropometric measurement of malnutrition in children in Zaria, Nigeria. Ann Trop Paediatr. 1983 Sep;3(3):143–151. doi: 10.1080/02724936.1983.11748286. [DOI] [PubMed] [Google Scholar]
  5. Clowes G. H., Jr, George B. C., Villee C. A., Jr, Saravis C. A. Muscle proteolysis induced by a circulating peptide in patients with sepsis or trauma. N Engl J Med. 1983 Mar 10;308(10):545–552. doi: 10.1056/NEJM198303103081001. [DOI] [PubMed] [Google Scholar]
  6. Dossetor J. F., Whittle H. C. Protein-losing enteropathy and malabsorption in acute measles enteritis. Br Med J. 1975 Jun 14;2(5971):592–593. doi: 10.1136/bmj.2.5971.592. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Halmagyi D. F., Kinney J. M. Metabolic rate in acute respiratory failure complicating sepsis. Surgery. 1975 Apr;77(4):492–497. [PubMed] [Google Scholar]
  8. Koster F. T., Curlin G. C., Aziz K. M., Haque A. Synergistic impact of measles and diarrhoea on nutrition and mortality in Bangladesh. Bull World Health Organ. 1981;59(6):901–908. [PMC free article] [PubMed] [Google Scholar]
  9. Long C. L. Energy balance and carbohydrate metabolism in infection and sepsis. Am J Clin Nutr. 1977 Aug;30(8):1301–1310. doi: 10.1093/ajcn/30.8.1301. [DOI] [PubMed] [Google Scholar]
  10. MORLEY D. THE SEVERE MEASLES OF WEST AFRICA. Proc R Soc Med. 1964 Sep;57:846–849. [PMC free article] [PubMed] [Google Scholar]
  11. Mata L. J., Kromal R. A., Urrutia J. J., Garcia B. Effect of infection on food intake and the nutritional state: perspectives as viewed from the village. Am J Clin Nutr. 1977 Aug;30(8):1215–1227. doi: 10.1093/ajcn/30.8.1215. [DOI] [PubMed] [Google Scholar]
  12. Wannemacher R. W., Jr, Dinterman R. E., Pekarek R. S., Bartelloni P. J., Beisel W. R. Urinary amino acid excretion during experimentally induced sandfly fever in man. Am J Clin Nutr. 1975 Feb;28(2):110–118. doi: 10.1093/ajcn/28.2.110. [DOI] [PubMed] [Google Scholar]
  13. Waterlow J. C., Buzina R., Keller W., Lane J. M., Nichaman M. Z., Tanner J. M. The presentation and use of height and weight data for comparing the nutritional status of groups of children under the age of 10 years. Bull World Health Organ. 1977;55(4):489–498. [PMC free article] [PubMed] [Google Scholar]
  14. Whittle H. C., Smith J. S., Kogbe O. I., Dossetor J., Duggan M. Severe ulcerative herpes of mouth and eye following measles. Trans R Soc Trop Med Hyg. 1979;73(1):66–69. doi: 10.1016/0035-9203(79)90132-9. [DOI] [PubMed] [Google Scholar]

Articles from Archives of Disease in Childhood are provided here courtesy of BMJ Publishing Group

RESOURCES