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. 1972 Nov 18;4(5837):413–415. doi: 10.1136/bmj.4.5837.413

Radioactive Bromide Partition Test in Differential Diagnosis of Tuberculous Meningitis

B K Mandal, D I K Evans, A G Ironside, B R Pullan
PMCID: PMC1786665  PMID: 4637157

Abstract

In 19 cases of lymphocytic meningitis, the radioactive bromide partition test showed that four were tuberculous and 15 viral in origin. In all the tuberculous cases the serum/cerebrospinal fluid bromide ratio was below a critical value of 1·6, and in all the cases of viral meningitis the ratio was above this value. The test may be particularly helpful when diagnosis is difficult. The test may prove to be a valuable and justified additional procedure in the early diagnosis of tuberculous meningitis.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. CROOK A., DUNCAN H., GUTTERIDGE B., PALLIS C. Use of 82Br in differential diagnosis of lymphocytic meningitis. Br Med J. 1960 Mar 5;1(5174):704–706. doi: 10.1136/bmj.1.5174.704. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Kocen R. S., Parsons M. Neurological complications of tuberculosis: some unusual manifestations. Q J Med. 1970 Jan;39(153):17–30. [PubMed] [Google Scholar]
  3. Mouchette R., Merchie G., Chantraine J. M. L'épreuve au brome radio-actif et son intérêt dans le diagnostic des méningites tuberculeuses. Rev Med Liege. 1966 Apr 15;21(8):181–185. [PubMed] [Google Scholar]
  4. NICOL V. S., FAWNS H. T. Observations on the bromide partition test in the diagnosis of non-purulent meningitis. Arch Dis Child. 1958 Oct;33(171):440–444. doi: 10.1136/adc.33.171.440. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. SMITH H. V., TAYLOR L. M., HUNTER G. The blood-cerebrospinal fluid barrier in tuberculous meningitis and allied conditions. J Neurol Neurosurg Psychiatry. 1955 Nov;18(4):237–249. doi: 10.1136/jnnp.18.4.237. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. TAYLOR L. M., SMITH H. V., HUNTER G. The blood-C.S.F. barrier to bromide in diagnosis of tuberculous meningitis. Lancet. 1954 Apr 3;266(6814):700–702. doi: 10.1016/s0140-6736(54)92108-x. [DOI] [PubMed] [Google Scholar]
  7. Wilfert C. M. Mumps meningoencephalitis with low cerebrospinal-fluid glucose, prolonged pleocytosis and elevation of protein. N Engl J Med. 1969 Apr 17;280(16):855–859. doi: 10.1056/NEJM196904172801603. [DOI] [PubMed] [Google Scholar]
  8. Wiseman R. A., Mahmood A. Unusual manifestations of tuberculosis. Br J Clin Pract. 1967 Jan;21(1):13–19. [PubMed] [Google Scholar]

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