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. 1972 Jun 3;2(5813):577–580. doi: 10.1136/bmj.2.5813.577

Persistence of treponemes after treatment.

E M Dunlop
PMCID: PMC1788090  PMID: 4555841

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Selected References

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  1. AGARWAL L. P. Aqueous humour examination in granulomatous iridocyclitis. Doc Ophthalmol. 1960;14:97–110. doi: 10.1007/BF00182919. [DOI] [PubMed] [Google Scholar]
  2. Alford C. A., Jr, Polt S. S., Cassady G. E., Straumfjord J. V., Remington J. S. Gamma-M-fluorescent treponemal antibody in the diagnosis of congenital syphilis. N Engl J Med. 1969 May 15;280(20):1086–1091. doi: 10.1056/NEJM196905152802002. [DOI] [PubMed] [Google Scholar]
  3. Atwoo W. G., Miller J. L., Stout G. W., Norins L. C. The TPI and FTA-ABS tests in treated late syphilis. JAMA. 1968 Feb 19;203(8):549–551. doi: 10.1001/jama.203.8.549. [DOI] [PubMed] [Google Scholar]
  4. Atwood W. G., Miller J. L. The immunoglobulin class of fluorescent treponemal antibodies in syphilis. Int J Dermatol. 1970 Oct-Dec;9(4):259–266. doi: 10.1111/j.1365-4362.1970.tb04739.x. [DOI] [PubMed] [Google Scholar]
  5. BEKKER J. H. Limitations of the Reiter protein complement-fixation (RPCF) test. Br J Vener Dis. 1962 Sep;38:131–133. doi: 10.1136/sti.38.3.131. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Barwell C. F., Dunlop E. M., Race J. W. Results of complement-fixation and intradermal tests for Bedsoniae in genital infection, disease of the eye and Reiter's disease. Am J Ophthalmol. 1967 May;63(5 Suppl):1527–1534. doi: 10.1016/0002-9394(67)94142-6. [DOI] [PubMed] [Google Scholar]
  7. COLLART P., BOREL L. J., DUREL P. SIGNIFICANCE OF SPIRAL ORGANISMS FOUND, AFTER TREATMENT, IN LATE HUMAN AND EXPERIMENTAL SYPHILIS. Br J Vener Dis. 1964 Jun;40:81–89. doi: 10.1136/sti.40.2.81. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. COLLART P., BOREL L. J., DUREL P. [Research on the effectiveness of penicillin therapy during late experimental and human syphilis]. Ann Dermatol Syphiligr (Paris) 1962 Sep-Oct;89:488–504. [PubMed] [Google Scholar]
  9. COLLIER L. H., DUKE-ELDER S., JONES B. R. Experimental trachoma produced by cultured virus. Br J Ophthalmol. 1958 Dec;42(12):705–720. doi: 10.1136/bjo.42.12.705. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. COLLIER L. H. On the aetiology and relationship of trachoma and inclusion blennorrhoea. Rev Int Trach. 1960;37:585–599. [PubMed] [Google Scholar]
  11. Cannefax G. R., Hanson A. W., Skaggs R., Jr An investigation of sorbing substances in the FTA-ABS test for syphilis. Public Health Rep. 1968 May;83(5):411–416. [PMC free article] [PubMed] [Google Scholar]
  12. Carr R. D., Becker S. W., Carpenter C. M. The biological false-positive phenomenon in elderly men. Arch Dermatol. 1966 Apr;93(4):393–395. [PubMed] [Google Scholar]
  13. Chandler F. W., Jr A technique for detecting Treponema pallidum through the use of membrane filters and immunofluorescence staining. Br J Vener Dis. 1969 Dec;45(4):305–307. doi: 10.1136/sti.45.4.305. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Christman E. H., Hamilton R. W., Heaton C. L., Hoffmeyer I. M. Intraocular treponemes. Arch Ophthalmol. 1968 Sep;80(3):303–307. doi: 10.1001/archopht.1968.00980050305002. [DOI] [PubMed] [Google Scholar]
  15. DEACON W. E., FALCONE V. H., HARRIS A. A fluorescent test for treponemal antibodies. Proc Soc Exp Biol Med. 1957 Nov;96(2):477–480. doi: 10.3181/00379727-96-23512. [DOI] [PubMed] [Google Scholar]
  16. DEACON W. E., FREEMAN E. M., HARRIS A. Fluorescent treponemal antibody test. Modification based on quantitation (FTA-200). Proc Soc Exp Biol Med. 1960 Apr;103:827–829. doi: 10.3181/00379727-103-25685. [DOI] [PubMed] [Google Scholar]
  17. DUNLOP E. M., JONES B. R., AL-HUSSAINI M. K. GENITAL INFECTION IN ASSOCIATION WITH TRIC VIRUS INFECTION OF THE EYE. III. CLINICAL AND OTHER FINDINGS. PRELIMINARY REPORT. Br J Vener Dis. 1964 Mar;40:33–42. doi: 10.1136/sti.40.1.33. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Darougar S., Treharne J. D., Dwyer R. S., Kinnison J. R., Jones B. R. Isolation of TRIC agent (Chlamydia) in irradiated McCoy cell culture from endemic trachoma in field studies in Iran. Comparison with other laboratory tests for detection of Chlamydia. Br J Ophthalmol. 1971 Sep;55(9):591–599. doi: 10.1136/bjo.55.9.591. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Deacon W. E., Lucas J. B., Price E. V. Fluorescent treponemal antibody-absorption (FTA-ABS) test for syphilis. JAMA. 1966 Nov 7;198(6):624–628. [PubMed] [Google Scholar]
  20. Degos R., Touraine R., Collart P., Daniel F., Audebert G. Syphilis maligne précoce d'évolution mortelle (avec examen anatomique) Bull Soc Fr Dermatol Syphiligr. 1970 Jul;77(1):10–15. [PubMed] [Google Scholar]
  21. Dunlop E. M., Hare M. J., Darougar S., Jones B. R., Rice N. S. Detection of Chlamydia (Bedsonia) in certain infections of man. II. Clinical study of genital tract, eye, rectum, and other sites of recovery of Chlamydia. J Infect Dis. 1969 Oct;120(4):463–470. doi: 10.1093/infdis/120.4.463. [DOI] [PubMed] [Google Scholar]
  22. Escobar M. R., Dalton H. P., Allison M. J. Fluorescent antibody tests for syphilis using cerebrospinal fluid: clinical correlation in 150 cases. Am J Clin Pathol. 1970 Jun;53(6):886–890. doi: 10.1093/ajcp/53.6.886. [DOI] [PubMed] [Google Scholar]
  23. Förström L., Lassus A., Jokinen E. J. False positive reactions to the Reiter protein complement-fixation (RPCF) test. Br J Vener Dis. 1969 Jun;45(2):126–128. doi: 10.1136/sti.45.2.126. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. GORDON F. B., QUAN A. L. OCCURENCE OF GLYCOGEN IN INCLUSIONS OF THE PSITTACOSIS-LYMPHOGRANULOMA VENEREUM-TRACHOMA AGENTS. J Infect Dis. 1965 Apr;115:186–196. doi: 10.1093/infdis/115.2.186. [DOI] [PubMed] [Google Scholar]
  25. Gager W. E., Smith J. L., Israel C. W. Nasopharyngeal syphilis with blindness. Arch Otolaryngol. 1969 Nov;90(5):641–646. doi: 10.1001/archotol.1969.00770030643022. [DOI] [PubMed] [Google Scholar]
  26. Garner M. F., Backhouse J. L. Fluorescent treponemal antibody tests on cerebrospinal fluid. Br J Vener Dis. 1971 Oct;47(5):356–358. doi: 10.1136/sti.47.5.356. [DOI] [PMC free article] [PubMed] [Google Scholar]
  27. Garner M. F., Robson J. H. An immunofluorescence method for the diagnosis of primary syphilis using an absorption technique. J Clin Pathol. 1968 Sep;21(5):576–577. doi: 10.1136/jcp.21.5.576. [DOI] [PMC free article] [PubMed] [Google Scholar]
  28. Golden B., Watzke R. C., Lindell S. S., McKee A. P. Treponemal-like organisms in the aqueous of nonsyphilitic patients. An immunologic study. Arch Ophthalmol. 1968 Dec;80(6):727–731. doi: 10.1001/archopht.1968.00980050729010. [DOI] [PubMed] [Google Scholar]
  29. Goldman E. E., McLain J. H., Smith J. L. Penicillins and aqueous humor. Am J Ophthalmol. 1968 May;65(5):717–721. doi: 10.1016/0002-9394(68)94387-0. [DOI] [PubMed] [Google Scholar]
  30. Goldman J. N., Lantz M. A. FTA-ABS and VDRL slide test reactivity in a population of nuns. JAMA. 1971 Jul 5;217(1):53–55. [PubMed] [Google Scholar]
  31. Gordon F. B., Dressler H. R., Quan A. L. Relative sensitivity of cell culture and yolk sac for detection of TRIC infection. Am J Ophthalmol. 1967 May;63(5 Suppl):1044–1048. doi: 10.1016/0002-9394(67)94080-9. [DOI] [PubMed] [Google Scholar]
  32. Gordon F. B., Harper I. A., Quan A. L., Treharne J. D., Dwyer R. S., Garland J. A. Detection of Chlamydia (Bedsonia) in certain infections of man. I. Laboratory procedures: comparison of yolk sac and cell culture for detection and isolation. J Infect Dis. 1969 Oct;120(4):451–462. doi: 10.1093/infdis/120.4.451. [DOI] [PubMed] [Google Scholar]
  33. Grossman L. J., Peery T. M. Biologically false-positive serologic tests for syphilis due to smallpox vaccination. Am J Clin Pathol. 1969 Mar;51(3):375–378. doi: 10.1093/ajcp/51.3.375. [DOI] [PubMed] [Google Scholar]
  34. HUNTER E. F., DEACON W. E., MEYER P. E. AN IMPROVED FTA TEST FOR SYPHILIS, THE ABSORPTION PROCEDURE (FTA-ABS). Public Health Rep. 1964 May;79:410–412. [PMC free article] [PubMed] [Google Scholar]
  35. Hardy J. B., Hardy P. H., Oppenheimer E. H., Ryan S. J., Jr, Sheff R. N. Failure of penicillin in a newborn with congenital syphilis. JAMA. 1970 May 25;212(8):1345–1349. [PubMed] [Google Scholar]
  36. Harvey A. M., Shulman L. E. Connective tissue disease and the chronic biologic false-positive test for syphilis (BFP reaction). Med Clin North Am. 1966 Sep;50(5):1271–1279. [PubMed] [Google Scholar]
  37. JONES B. R., COLLIER L. H., SMITH C. H. Isolation of virus from inclusion blennorrhoea. Lancet. 1959 May 2;1(7079):902–905. doi: 10.1016/s0140-6736(59)91307-8. [DOI] [PubMed] [Google Scholar]
  38. Jokinen E. J., Lassus A., Linder E. Fluorescent treponemal antibody (FTA) reaction in sera with antinuclear factors. Ann Clin Res. 1969 May;1(1):77–80. [PubMed] [Google Scholar]
  39. Jones B. R. Advances and prospects in the study of certain diseases due to infections by subgroup A Chlamydia. Br J Vener Dis. 1972 Feb;48(1):13–17. doi: 10.1136/sti.48.1.13. [DOI] [PMC free article] [PubMed] [Google Scholar]
  40. Király K., Jobbágy A., Kováts L. Group antibodies in fluorescent treponemal antibody (FTA) test. J Invest Dermatol. 1967 Jan;48(1):98–100. doi: 10.1038/jid.1967.15. [DOI] [PubMed] [Google Scholar]
  41. Kraus S. J., Haserick J. R., Logan L. C., Bullard J. C. Atypical fluorescence in the fluorescent treponemal-antibody-absorption (FTA-ABS) test related to deoxyribonucleic acid (DNA) antibodies. J Immunol. 1971 Jun;106(6):1665–1669. [PubMed] [Google Scholar]
  42. LYNCH F. W., KIMBALL A. C., KERNAN P. D. Serologic tests for syphilis following smallpox vaccination and including Reiter protein complement fixation technic. J Invest Dermatol. 1960 Mar;34:219–222. doi: 10.1038/jid.1960.33. [DOI] [PubMed] [Google Scholar]
  43. Lawton Smith J., Israel C. W. Recovery of spirochagetes in the monkey by passive transfer from human late sero-negative syphilis. Br J Vener Dis. 1968 Jun;44(2):109–115. doi: 10.1136/sti.44.2.109. [DOI] [PMC free article] [PubMed] [Google Scholar]
  44. Levine B. M., Smith J. L., Martinez S. A., Montenegro E. N., Nicol W. G. VDRL test in normal albino and pigmented rabbits. Br J Vener Dis. 1969 Sep;45(3):197–199. doi: 10.1136/sti.45.3.197. [DOI] [PMC free article] [PubMed] [Google Scholar]
  45. MILLER J. L., BRODEY M., HILL J. H. Laboratory studies in a series of biologic false-positive reactors. AMA Arch Derm. 1959 Feb;79(2):206–212. doi: 10.1001/archderm.1959.01560140068010. [DOI] [PubMed] [Google Scholar]
  46. MILLER J. L., BRODEY M., HILL J. H. Studies on significance of biologic false-positive reaction. J Am Med Assoc. 1957 Jul 27;164(13):1461–1465. doi: 10.1001/jama.1957.02980130037009. [DOI] [PubMed] [Google Scholar]
  47. Mackey D. M., Price E. V., Knox J. M., Scotti A. Specificity of the FTA-ABS test for syphilis. JAMA. 1969 Mar 3;207(9):1683–1685. [PubMed] [Google Scholar]
  48. Manikowska-Lesińska W., Jakubowski A. Relationship of antibodies detected by the immunofluorescence method with the various classes of immunoglobulins in cases of untreated syphilis. Br J Vener Dis. 1970 Oct;46(5):380–382. doi: 10.1136/sti.46.5.380. [DOI] [PMC free article] [PubMed] [Google Scholar]
  49. NELSON R. A., Jr, MAYER M. M. Immobilization of Treponema pallidum in vitro by antibody produced in syphilitic infection. J Exp Med. 1949 Apr 1;89(4):369–393. doi: 10.1084/jem.89.4.369. [DOI] [PMC free article] [PubMed] [Google Scholar]
  50. PORTNOY J., BREWER J. H., HARRIS A. Rapid plasma reagin card test for syphilis and other treponematoses. Public Health Rep. 1962 Aug;77:645–652. [PMC free article] [PubMed] [Google Scholar]
  51. Quaife R. A., Gostling J. V. False positive Wassermann reaction associated with evidence of enterovirus infection. J Clin Pathol. 1971 Mar;24(2):120–121. doi: 10.1136/jcp.24.2.120. [DOI] [PMC free article] [PubMed] [Google Scholar]
  52. Rathlev T. Evaluation of the sorbents used in the FTA-ABS test. Br J Vener Dis. 1968 Dec;44(4):295–298. doi: 10.1136/sti.44.4.295. [DOI] [PMC free article] [PubMed] [Google Scholar]
  53. Rathlev T. Haemagglutination test utilizing pathogenic Treponema pallidum for the sero-diagnosis of syphilis. Br J Vener Dis. 1967 Sep;43(3):181–185. doi: 10.1136/sti.43.3.181. [DOI] [PMC free article] [PubMed] [Google Scholar]
  54. Rice N. S., Dunlop E. M., Jones B. R., Hare M. J., King A. J., Rodin P., Mushin A., Wilkinson A. E. Demonstration of treponeme-like forms in cases of treated and untreated late syphilis and of treated early syphilis. Br J Vener Dis. 1970 Feb;46(1):1–9. doi: 10.1136/sti.46.1.1. [DOI] [PMC free article] [PubMed] [Google Scholar]
  55. Salo O. P., Somer T., Aho K., Cantell K. Studies of false positive serological tests for syphilis following smallpox vaccination. Ann Med Exp Biol Fenn. 1966;44(2):304–306. [PubMed] [Google Scholar]
  56. Scotti A. T., Logan L. A specific IgM antibody test in neonatal congenital syphilis. J Pediatr. 1968 Aug;73(2):242–243. doi: 10.1016/s0022-3476(68)80075-7. [DOI] [PubMed] [Google Scholar]
  57. Smith J. L., Israel C. W., McCrary J. A., Harner R. E. Recovery of Treponema pallidum from aqueous humor removed at cataract surgery in man by passive transfer to rabbit testis. Am J Ophthalmol. 1968 Feb;65(2):242–247. doi: 10.1016/0002-9394(68)93595-2. [DOI] [PubMed] [Google Scholar]
  58. Sparling P. F. Diagnosis and treatment of syphilis. N Engl J Med. 1971 Mar 25;284(12):642–653. doi: 10.1056/NEJM197103252841205. [DOI] [PubMed] [Google Scholar]
  59. TANG F. F., CHANG H. L., HUANG Y. T., WANG K. C. Studies on the etiology of trachoma with special reference to isolation of the virus in chick embryo. Chin Med J. 1957 Jun;75(6):429–447. [PubMed] [Google Scholar]
  60. Thygeson P. Historical review of oculogenital disease. Am J Ophthalmol. 1971 May;71(5):975–985. doi: 10.1016/0002-9394(71)90562-9. [DOI] [PubMed] [Google Scholar]
  61. Tipper D. J., Strominger J. L. Biosynthesis of the peptidoglycan of bacterial cell walls. XII. Inhibition of cross-linking by penicillins and cephalosporins: studies in Staphylococcus aureus in vivo. J Biol Chem. 1968 Jun 10;243(11):3169–3179. [PubMed] [Google Scholar]
  62. Tipper D. J., Strominger J. L. Mechanism of action of penicillins: a proposal based on their structural similarity to acyl-D-alanyl-D-alanine. Proc Natl Acad Sci U S A. 1965 Oct;54(4):1133–1141. doi: 10.1073/pnas.54.4.1133. [DOI] [PMC free article] [PubMed] [Google Scholar]
  63. Tomizawa T. Hemagglutination tests for diagnosis of syphilis. A preliminary report. Jpn J Med Sci Biol. 1966 Dec;19(6):305–308. doi: 10.7883/yoken1952.19.305. [DOI] [PubMed] [Google Scholar]
  64. Treharne J. D., Davey S. J., Gray S. J., Jones B. R. Immunological classification of TRIC agents and of some recently isolated LGV agents by the micro-immunofluorescence test. Br J Vener Dis. 1972 Feb;48(1):18–25. doi: 10.1136/sti.48.1.18. [DOI] [PMC free article] [PubMed] [Google Scholar]
  65. Tringali G. R., Cox P. M. Reactivity in the FTA-ABS test of rabbits hyperimmunized with nonpathogenic treponemes. Br J Vener Dis. 1970 Aug;46(4):313–317. doi: 10.1136/sti.46.4.313. [DOI] [PMC free article] [PubMed] [Google Scholar]
  66. Tuffanelli D. L. False-positive reactions for syphilis. Serological abnormalities in relatives of chronic reactors. Arch Dermatol. 1968 Dec;98(6):606–611. [PubMed] [Google Scholar]
  67. Turner T. B., Hardy P. H., Newman B. Infectivity tests in syphilis. Br J Vener Dis. 1969 Sep;45(3):183–195. doi: 10.1136/sti.45.3.183. [DOI] [PMC free article] [PubMed] [Google Scholar]
  68. WILLCOX R. R. IMPLICATIONS OF THE REPORTED FINDING OF TREPONEMES OF LITTLE OR NO VIRULENCE AFTER THE TREATMENT OF SYPHILIS WITH PENICILLIN. Br J Vener Dis. 1964 Jun;40:90–95. doi: 10.1136/sti.40.2.90. [DOI] [PMC free article] [PubMed] [Google Scholar]
  69. Wang S. P., Grayston J. T. Immunologic relationship between genital TRIC, lymphogranuloma venereum, and related organisms in a new microtiter indirect immunofluorescence test. Am J Ophthalmol. 1970 Sep;70(3):367–374. doi: 10.1016/0002-9394(70)90096-6. [DOI] [PubMed] [Google Scholar]
  70. Whitfield R., Wirostko E. Uveitis and intraocular treponemes. Arch Ophthalmol. 1970 Jul;84(1):12–15. doi: 10.1001/archopht.1970.00990040014004. [DOI] [PubMed] [Google Scholar]
  71. Wilkinson A. E., Cowell L. P. Immunofluorescent staining for the detection of Treponema pallidum in early syphilitic lesions. Br J Vener Dis. 1971 Aug;47(4):252–254. doi: 10.1136/sti.47.4.252. [DOI] [PMC free article] [PubMed] [Google Scholar]
  72. Wilkinson A. E., Ferguson H. G. Some observations on the sorbing agent used in the absorbed fluorescent treponemal antibody (FTA-ABS) test. Br J Vener Dis. 1968 Dec;44(4):291–294. doi: 10.1136/sti.44.4.291. [DOI] [PMC free article] [PubMed] [Google Scholar]
  73. Wilkinson A. E. Fluorescent treponemal antibody inhibition test. Br J Vener Dis. 1967 Sep;43(3):186–190. doi: 10.1136/sti.43.3.186. [DOI] [PMC free article] [PubMed] [Google Scholar]
  74. Wilkinson A. E., Rayner C. F. Studies on the fluorescent treponemal antibody (FTA) test. Br J Vener Dis. 1966 Mar;42(1):8–15. doi: 10.1136/sti.42.1.8. [DOI] [PMC free article] [PubMed] [Google Scholar]
  75. Wilkinson A. E. Study of late ocular syphilis. Demonstration of treponemes in aqueous humour and cerebrospinal fluid. I. Methods of demonstration of treponemes. Trans Ophthalmol Soc U K. 1969;88:251–256. [PubMed] [Google Scholar]
  76. Wilkinson A. E., Wiseman C. C. The role of sorbent in the absorbed fluorescent treponemal antibody (FTA-ABS) test. Proc R Soc Med. 1971 Apr;64(4):422–425. [PMC free article] [PubMed] [Google Scholar]
  77. Wright D. J., Doniach D., Lessof M. H., Turk J. L., Grimble A. S., Catterall R. D. New antibody in early syphilis. Lancet. 1970 Apr 11;1(7650):740–743. doi: 10.1016/s0140-6736(70)90972-4. [DOI] [PubMed] [Google Scholar]
  78. YOBS A. R., ROCKWELL D. H., CLARK J. W., Jr TREPONEMAL SURVIVAL IN HUMANS AFTER PENICILLIN THERAPY: A PRELIMINARY REPORT. Br J Vener Dis. 1964 Dec;40:248–253. doi: 10.1136/sti.40.4.248. [DOI] [PMC free article] [PubMed] [Google Scholar]
  79. Yobs A. R., Clark J. W., Jr, Mothershed S. E., Bullard J. C., Artley C. W. Further observations on the persistence of Treponema pallidum after treatment in rabbits and humans. Br J Vener Dis. 1968 Jun;44(2):116–130. doi: 10.1136/sti.44.2.116. [DOI] [PMC free article] [PubMed] [Google Scholar]
  80. Yobs A. R., Olansky S., Rockwell D. H., Clark J. W., Jr Do treponemes survive adequate treatment of late syphilis? Arch Dermatol. 1965 Apr;91(4):379–389. doi: 10.1001/archderm.91.4.379. [DOI] [PubMed] [Google Scholar]
  81. de BRUIJN J. Reiter treponene in syphilis serology. Br J Vener Dis. 1962 Sep;38:126–130. doi: 10.1136/sti.38.3.126. [DOI] [PMC free article] [PubMed] [Google Scholar]

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