Abstract
To evaluate the efficacy of a Haemophilus somnus bacterin a total of 1114 beef calves or yearling bulls were used in the province of Saskatchewan. The six herds were included in a vaccination trial in which the vaccine was administered subcutaneously in one or two doses. The prevalence of H. somnus in nasal swabs of these animals at the time of the initial vaccination was 0.35% Postvaccination information on morbidity and mortality for a four month period was requested from the five ranches where there were nonvaccinated control calves. Postvaccination outbreaks of infectious thromboembolic meningoencephalitis occurred in two of these herds and, although the numbers were limited, there was a trend to reduced morbidity and mortality in the vaccinated animals compared to controls. Seroconversion rates, as determined by the complement fixation test, in the six herds were 28.3% for control calves, 57% for animals vaccinated once and 80.3% for animals vaccinated twice. On the basis of these results the bacterin was considered to be sufficiently efficacious to warrant its further evaluation under field conditions.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- BROWN W. W., GRINER L. A., JENSEN R. Infectious embolic meningo-encephalitis in cattle. J Am Vet Med Assoc. 1956 Nov 1;129(9):417–421. [PubMed] [Google Scholar]
- Crandell R. A., Smith A. R., Kissil M. Colonization and transmission of Haemophilus somnus in cattle. Am J Vet Res. 1977 Nov;38(11):1749–1751. [PubMed] [Google Scholar]
- Hall R. F., Williams J. M., Smith G. L. Field evaluation of Haemophilus somnus bacterin. Vet Med Small Anim Clin. 1977 Aug;72(8):1368–1370. [PubMed] [Google Scholar]
- Hoerlein A. B., Goto K., Young S. Haemophilus somnus agglutinins in cattle. J Am Vet Med Assoc. 1973 Dec 15;163(12):1375–1377. [PubMed] [Google Scholar]
- Little P. B., Sorensen D. K. Bovine polioencephalomalacia, infectious embolic meningoencephalitis, and acute lead poisoning in feedlot cattle. J Am Vet Med Assoc. 1969 Dec 15;155(12):1892–1903. [PubMed] [Google Scholar]
- MacDonald D. W., Christian R. G., Chalmers G. A. Infectious thromboembolic meningoencephalitis: literature review and occurrence in Alberta, 1969-71. Can Vet J. 1973 Mar;14(3):57–61. [PMC free article] [PubMed] [Google Scholar]
- MacDonald D. W., Little P. B. Complement fixation titers in cattle following intranasal inoculation of Hemophilus somnus. Can J Comp Med. 1976 Oct;40(4):442–444. [PMC free article] [PubMed] [Google Scholar]
- Miesner A. W. Infectious thromboembolic meningoencephalitis (TEME) in an Iowa feedlot. Vet Med Small Anim Clin. 1978 Sep;73(9):1189–1190. [PubMed] [Google Scholar]
- Miller R. J., Renshaw H. W., Evans J. A. Haemophilus somnus complex: antigenicity and specificity of fractions of Haemophilus somnus. Am J Vet Res. 1975 Aug;36(08):1123–1128. [PubMed] [Google Scholar]
- Panciera R. J., Dahlgren R. R., Rinker H. B. Observations on septicemia of cattle caused by a haemophilus-like organism. Pathol Vet. 1968;5(3):212–216. doi: 10.1177/030098586800500303. [DOI] [PubMed] [Google Scholar]
- Saunders J. R., Olson S. M., Radostits O. M. Efficacy of an intramuscular infectious bovine rhinotraceitis vaccine against abortion due to the virus. Can Vet J. 1972 Dec;13(12):273–278. [PMC free article] [PubMed] [Google Scholar]
- Saunders J. R., Thiessen W. A., Janzen E. D. Haemophilus somnus infections I. A ten year (1969-1978) retrospective study of losses in cattle herds in Western Canada. Can Vet J. 1980 Apr;21(4):119–123. [PMC free article] [PubMed] [Google Scholar]
- Van Dreumel A. A., Curtis R. A., Ruhnke H. L. Infectious thromboembolic meningoencephalitis in Ontario feedlot cattle. Can Vet J. 1970 Jul;11(7):125–130. [PMC free article] [PubMed] [Google Scholar]
- Williams J. M., Smith G. L., Murdock F. M. Immunogenicity of a Haemophilus somnus bacterin in cattle. Am J Vet Res. 1978 Nov;39(11):1756–1762. [PubMed] [Google Scholar]