Abstract
Oxygen levels (tension, saturation, and content) in blood from varicose leg veins were found to be significantly lower than those in blood from normal leg veins at the same site on the limb under the same laboratory conditions. Treatment with hydroxyethylrutosides significantly increased the oxygen levels in blood from varicose veins, and this was associated with an improvement in leg symptoms attributable to venous insufficiency. Hydroxyethylrutosides have been shown to have a beneficial effect on capillary dysfunction in venous stasis.
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Selected References
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- Allen S. The treatment of chronic venous disorder of the leg. Practitioner. 1970 Aug;205(226):221–224. [PubMed] [Google Scholar]
- FONTAINE R. Remarks concerning venous thrombosis and its sequelae. Surgery. 1957 Jan;41(1):6–25. [PubMed] [Google Scholar]
- Fitzgerald D. E. A clinical trial of troxerutin in venous insufficiency of the lower limb. Practitioner. 1967 Mar;198(185):406–407. [PubMed] [Google Scholar]
- Ledingham I. M., McBride T. I., Parratt J. R., Vance J. P. The effect of hypercapnia on myocardial blood flow and metabolism. J Physiol. 1970 Sep;210(1):87–105. doi: 10.1113/jphysiol.1970.sp009197. [DOI] [PMC free article] [PubMed] [Google Scholar]
- McDowall D. G., Ledingham I. M., Tindal S. Alveolar-arterial gradients for oxygen at 1, 2, and 3 atmospheres absolute. J Appl Physiol. 1968 Mar;24(3):324–329. doi: 10.1152/jappl.1968.24.3.324. [DOI] [PubMed] [Google Scholar]
- McEwan A. J., Stalker C. G., Ledingham I. M. Foot skin ischaemia in atherosclerotic peripheral vascular disease. Br Med J. 1970 Sep 12;3(5723):612–615. doi: 10.1136/bmj.3.5723.612. [DOI] [PMC free article] [PubMed] [Google Scholar]
- PIULACHS P., VIDAL-BARRAQUER F. Pathogenic study of varicose veins. Angiology. 1953 Feb;4(1):59–99. doi: 10.1177/000331975300400108. [DOI] [PubMed] [Google Scholar]
- Rivoire J., Jaccoud P., Golden G., Horn R. L'oxymétrie sanguine dans le syndrome variqueux. Premiers résultats. J Med Lyon. 1970 Feb 5;51(180):501–515. [PubMed] [Google Scholar]
- Rose S. S. A report on the use of an hydroxyethylrutoside in symptoms due to venous back pressure and allied conditions in the lower limbs. Br J Clin Pract. 1970 Apr;24(4):161–164. [PubMed] [Google Scholar]
- TORRES G. E. VALIDATION OF OXYGEN ELECTRODE FOR BLOOD. J Appl Physiol. 1963 Sep;18:1008–1011. doi: 10.1152/jappl.1963.18.5.1008. [DOI] [PubMed] [Google Scholar]