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. 1971 Jun 5;2(5761):555–557. doi: 10.1136/bmj.2.5761.555

Oedema in Rheumatoid Arthritis: Changes in the Coefficient of Capillary Filtration

Malcolm I V Jayson, Jenny S Barks
PMCID: PMC1795866  PMID: 5579191

Abstract

The rate of formation of tissue fluid for a given increase of venous pressure and for a known volume of tissue has been measured in the forearm. There is a significant increase in this figure in rheumatoid arthritis and a still greater increase in patients who develop recurrent oedema. This increase could not be attributed to steroid or phenylbutazone therapy, nor to a fall in the serum albumin. The results imply that there is some generalized abnormality in capillary function in rheumatoid disease and that this change is not limited to the joints.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. CELANDER O., MARILD K. Regional circulation and capillary filtration in relation to capillary exchange in the foot and calf of the newborn infant. Acta Paediatr. 1962 Jul;51:385–400. doi: 10.1111/j.1651-2227.1962.tb06561.x. [DOI] [PubMed] [Google Scholar]
  2. CONSDEN R., SMITH M. PROTEIN CONCENTRATION OF OEDEMA FLUID IN RHEUMATOID ARTHRITIS. II. Ann Rheum Dis. 1965 May;24:239–245. doi: 10.1136/ard.24.3.239. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. CROCKETT D. J. The protein levels of oedema fluids. Lancet. 1956 Dec 8;271(6954):1179–1182. doi: 10.1016/s0140-6736(56)90053-8. [DOI] [PubMed] [Google Scholar]
  4. GANDY R. H., ANSELL B. M., BYWATERS E. G. PROTEIN CONCENTRATION OF OEDEMA FLUID IN RHEUMATOID ARTHRITIS. I. Ann Rheum Dis. 1965 May;24:234–239. doi: 10.1136/ard.24.3.234. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Goode J. D. Synovial rupture of the elbow joint. Ann Rheum Dis. 1968 Nov;27(6):604–609. doi: 10.1136/ard.27.6.604. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Jayson M. I., Dixon A. S. Valvular mechanisms in juxta-articular cysts. Ann Rheum Dis. 1970 Jul;29(4):415–420. doi: 10.1136/ard.29.4.415. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Jayson M. I., Swannell A. J., Kirk J. A., Dixon S. J. Acute joint rupture. Ann Phys Med. 1969 Nov;10(4):175–179. doi: 10.1093/rheumatology/10.4.175. [DOI] [PubMed] [Google Scholar]
  8. Jue J., Entrup R. W., Hughes M., Narang G., Wégria R. Rate of movement of interstitial fluid: a factor in the pathogenesis of edema. Am J Physiol. 1970 Apr;218(4):1003–1009. doi: 10.1152/ajplegacy.1970.218.4.1003. [DOI] [PubMed] [Google Scholar]
  9. KITCHIN A. H. Peripheral blood flow and capillary filtration rates. Br Med Bull. 1963 May;19:155–160. doi: 10.1093/oxfordjournals.bmb.a070036. [DOI] [PubMed] [Google Scholar]
  10. Kalliomäki J. L., Vastamäki M. Chronic diffuse oedema of the rheumatoid hand: a sign of local lymphatic involvement. Ann Rheum Dis. 1968 Mar;27(2):167–169. doi: 10.1136/ard.27.2.167. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Landis E. M., Gibbon J. H. THE EFFECTS OF TEMPERATURE AND OF TISSUE PRESSURE ON THE MOVEMENT OF FLUID THROUGH THE HUMAN CAPILLARY WALL. J Clin Invest. 1933 Jan;12(1):105–138. doi: 10.1172/JCI100482. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. PAPPENHEIMER J. R. Passage of molecules through capillary wals. Physiol Rev. 1953 Jul;33(3):387–423. doi: 10.1152/physrev.1953.33.3.387. [DOI] [PubMed] [Google Scholar]
  13. Redisch W., Messina E. J., Hughes G., McEwen C. Capillaroscopic observations in rheumatic diseases. Ann Rheum Dis. 1970 May;29(3):244–253. doi: 10.1136/ard.29.3.244. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Robertson M. D., Hart F. D., White W. F., Nuki G., Boardman P. L. Rheumatoid lymphadenopathy. Ann Rheum Dis. 1968 May;27(3):253–260. doi: 10.1136/ard.27.3.253. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. SWINBURNE K. OEDEMA OF FEET AND ANKLES IN RHEUMATOID ARTHRITIS. Br Med J. 1964 Jun 13;1(5397):1541–1544. doi: 10.1136/bmj.1.5397.1541. [DOI] [PMC free article] [PubMed] [Google Scholar]

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