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. 1971 Jul 3;3(5765):9–12. doi: 10.1136/bmj.3.5765.9

Mechanism of Hyperventilation in Acute Cerebrovascular Accidents

D J Lane, M W Rout, D H Williamson
PMCID: PMC1800058  PMID: 5091917

Abstract

Lumbar cerebrospinal fluid and arterial blood acid-base state were assessed in 19 patients within 24 hours of an acute cerebrovascular accident. Those with haemorrhage into the C.S.F. showed a lower C.S.F. pH and higher C.S.F. lactate than those without haemorrhage but the Pco2, was similar in the two groups, suggesting that this greater C.S.F. acidity was not responsible for a greater degree of hyperventilation. In those without haemorrhage an inverse relation was found between C.S.F. pH and arterial Pco2, suggesting that a non-chemical ventilatory drive—for example, due to central neurological damage—was responsible for the acid-base changes observed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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