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. 1986 Mar;29(3):511–514. doi: 10.1128/aac.29.3.511

A novel type of resistance plasmid in Haemophilus influenzae.

J C Piffaretti, T Camponovo, B Borer-Bigliardi, A Arini
PMCID: PMC180424  PMID: 3013086

Abstract

Resistance plasmids of a novel type were found in two Haemophilus influenzae clinical isolates. pPJ301 and pPJ302 are 10.0 kilobases in size, carry a Tn2-like transposable element, and are related only by their common beta-lactamase genes to the other two types of resistance plasmids known to occur in H. influenzae.

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Selected References

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  1. Arini A., Peduzzi R., Piffaretti J. C. Epidémiologie de Neisseria gonorrhoeae isolées en Suisse: sensibilité aux antibiotiques et auxotypie. Schweiz Med Wochenschr. 1983 Apr 2;113(13):462–470. [PubMed] [Google Scholar]
  2. Bennett P. M., Grinsted J., Richmond M. H. Transposition of TnA does not generate deletions. Mol Gen Genet. 1977 Jul 20;154(2):205–211. doi: 10.1007/BF00330839. [DOI] [PubMed] [Google Scholar]
  3. Berg D. E., Davies J., Allet B., Rochaix J. D. Transposition of R factor genes to bacteriophage lambda. Proc Natl Acad Sci U S A. 1975 Sep;72(9):3628–3632. doi: 10.1073/pnas.72.9.3628. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Birnboim H. C., Doly J. A rapid alkaline extraction procedure for screening recombinant plasmid DNA. Nucleic Acids Res. 1979 Nov 24;7(6):1513–1523. doi: 10.1093/nar/7.6.1513. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Brunton J., Meier M., Ehrman N., Maclean I., Slaney L., Albritton W. L. Molecular epidemiology of beta-lactamase-specifying plasmids of Haemophilus ducreyi. Antimicrob Agents Chemother. 1982 Jun;21(6):857–863. doi: 10.1128/aac.21.6.857. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Chandler M., Allet B., Gallay E., Boy de La Tour E., Caro L. Involvement of IS1 in the dissociation of the r-determinant and RTF components of the plasmid R100.1. Mol Gen Genet. 1977 Jun 24;153(3):289–295. doi: 10.1007/BF00431594. [DOI] [PubMed] [Google Scholar]
  7. Clewell D. B., Helinski D. R. Supercoiled circular DNA-protein complex in Escherichia coli: purification and induced conversion to an opern circular DNA form. Proc Natl Acad Sci U S A. 1969 Apr;62(4):1159–1166. doi: 10.1073/pnas.62.4.1159. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. De Graaff J., Elwell L. P., Falkow S. Molecular nature of two beta-lactamase-specifying plasmids isolated from Haemophilus influenzae type b. J Bacteriol. 1976 Apr;126(1):439–446. doi: 10.1128/jb.126.1.439-446.1976. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Elwell L. P., Saunders J. R., Richmond M. H., Falkow S. Relationships among some R plasmids found in Haemophilus influenzae. J Bacteriol. 1977 Jul;131(1):356–362. doi: 10.1128/jb.131.1.356-362.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Fayet O., Froment Y., Piffaretti J. C. Beta-lactamase-specifying plasmids isolated from Neisseria gonorrhoeae have retained an intact right part of a Tn3-like transposon. J Bacteriol. 1982 Jan;149(1):136–144. doi: 10.1128/jb.149.1.136-144.1982. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Heffron F., McCarthy B. J., Ohtsubo H., Ohtsubo E. DNA sequence analysis of the transposon Tn3: three genes and three sites involved in transposition of Tn3. Cell. 1979 Dec;18(4):1153–1163. doi: 10.1016/0092-8674(79)90228-9. [DOI] [PubMed] [Google Scholar]
  12. Jahn G., Laufs R., Kaulfers P. M., Kolenda H. Molecular nature of two Haemophilus influenzae R factors containing resistances and the multiple integration of drug resistance transposons. J Bacteriol. 1979 May;138(2):584–597. doi: 10.1128/jb.138.2.584-597.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Kaulfers P. M., Laufs R., Jahn G. Molecular properties of transmissible R factors of Haemophilus influenzae determing tetracycline resistance. J Gen Microbiol. 1978 Apr;105(2):243–252. doi: 10.1099/00221287-105-2-243. [DOI] [PubMed] [Google Scholar]
  14. Laufs R., Kaulfers P. M., Jahn G., Teschner U. Molecular characterization of a small Haemophilus influenzae plasmid specifying beta-lactamase and its relationship to R factors from Neisseria gonorrhoeae. J Gen Microbiol. 1979 Mar;111(1):223–231. doi: 10.1099/00221287-111-1-223. [DOI] [PubMed] [Google Scholar]
  15. Laufs R., Riess F. C., Jahn G., Fock R., Kaulfers P. M. Origin of Haemophilus influenzae R factors. J Bacteriol. 1981 Aug;147(2):563–568. doi: 10.1128/jb.147.2.563-568.1981. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Mandel M., Higa A. Calcium-dependent bacteriophage DNA infection. J Mol Biol. 1970 Oct 14;53(1):159–162. doi: 10.1016/0022-2836(70)90051-3. [DOI] [PubMed] [Google Scholar]
  17. Piffaretti J. C., Fayet O. Phage-lambda-mediated transduction of non-conjugative plasmids is promoted by transposons. Gene. 1981 Apr;13(3):319–325. doi: 10.1016/0378-1119(81)90036-6. [DOI] [PubMed] [Google Scholar]
  18. Smith G. E., Summers M. D. The bidirectional transfer of DNA and RNA to nitrocellulose or diazobenzyloxymethyl-paper. Anal Biochem. 1980 Nov 15;109(1):123–129. doi: 10.1016/0003-2697(80)90019-6. [DOI] [PubMed] [Google Scholar]
  19. Stuy J. H. Chromosomally integrated conjugative plasmids are common in antibiotic-resistant Haemophilus influenzae. J Bacteriol. 1980 Jun;142(3):925–930. doi: 10.1128/jb.142.3.925-930.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Stuy J. H. Plasmid transfer in Haemophilus influenzae. J Bacteriol. 1979 Aug;139(2):520–529. doi: 10.1128/jb.139.2.520-529.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. van Klingeren B., van Embden J. D., Dessens-Kroon M. Plasmid-mediated chloramphenicol resistance in Haemophilus influenzae. Antimicrob Agents Chemother. 1977 Mar;11(3):383–387. doi: 10.1128/aac.11.3.383. [DOI] [PMC free article] [PubMed] [Google Scholar]

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