Abstract
Fumonisin B1 (FB1) was isolated from samples of forage grass originating in paddocks associated with an idiopathic disease of Canadian wapiti and wapiti-red deer hybrids characterized by “ill thrift” and liver dysfunction. Four of 40 samples contained 1, 3, 6, and 9 ppm (micrograms per gram) of FB1 and 4, 0.5, 2, and 0.5 ppm, respectively, of the methyl ester of FB1. Analyses were done by ion spray mass spectrometry and confirmed by both fast atom bombardment (solids probe) and mass spectral analysis by electron impact ionization of the trifluoroacetate derivative of the base hydrolyzed product (pentolamine) of FB1. This article contains the first report of the presence of fumonisin B1 in grass.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Gelderblom W. C., Kriek N. P., Marasas W. F., Thiel P. G. Toxicity and carcinogenicity of the Fusarium moniliforme metabolite, fumonisin B1, in rats. Carcinogenesis. 1991 Jul;12(7):1247–1251. doi: 10.1093/carcin/12.7.1247. [DOI] [PubMed] [Google Scholar]
- Korfmacher W. A., Chiarelli M. P., Lay J. O., Jr, Bloom J., Holcomb M., McManus K. T. Characterization of the mycotoxin fumonisin B1: comparison of thermospray, fast-atom bombardment and electrospray mass spectrometry. Rapid Commun Mass Spectrom. 1991 Oct;5(10):463–468. doi: 10.1002/rcm.1290051008. [DOI] [PubMed] [Google Scholar]
- Marasas W. F., Kellerman T. S., Gelderblom W. C., Coetzer J. A., Thiel P. G., van der Lugt J. J. Leukoencephalomalacia in a horse induced by fumonisin B1 isolated from Fusarium moniliforme. Onderstepoort J Vet Res. 1988 Dec;55(4):197–203. [PubMed] [Google Scholar]
- Ross P. F., Nelson P. E., Richard J. L., Osweiler G. D., Rice L. G., Plattner R. D., Wilson T. M. Production of fumonisins by Fusarium moniliforme and Fusarium proliferatum isolates associated with equine leukoencephalomalacia and a pulmonary edema syndrome in swine. Appl Environ Microbiol. 1990 Oct;56(10):3225–3226. doi: 10.1128/aem.56.10.3225-3226.1990. [DOI] [PMC free article] [PubMed] [Google Scholar]