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. 1988 Jul 2;297(6640):15–17. doi: 10.1136/bmj.297.6640.15

Dietary intake of calcium and postmenopausal bone loss.

J C Stevenson 1, M I Whitehead 1, M Padwick 1, J A Endacott 1, C Sutton 1, L M Banks 1, C Freemantle 1, T J Spinks 1, R Hesp 1
PMCID: PMC1834138  PMID: 3261612

Abstract

The use of calcium supplements to prevent postmenopausal bone loss and hence osteoporosis is widespread, but the evidence for their efficacy, either alone or in combination with other treatments, is contradictory. Skeletal measurements and dietary intake of calcium were determined in 59 healthy postmenopausal women, most of whom were within five years of the menopause. No correlation was found between current intake of calcium and either total calcium in the body or the density of trabecular or cortical bone in the forearm or vertebral trabecular bone. Dietary intake of calcium did not influence the rate of postmenopausal bone loss in the 54 women who completed 12 months of active or placebo treatment. Even when extremes of calcium intake were examined no difference was found in bone measurements between the women with the highest and lowest intakes. The results of this study suggest that the bone density of women in the early menopause is not influenced by current dietary intake of calcium.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Banks L. M., Stevenson J. C. Modified method of spinal computed tomography for trabecular bone mineral measurements. J Comput Assist Tomogr. 1986 May-Jun;10(3):463–467. doi: 10.1097/00004728-198605000-00001. [DOI] [PubMed] [Google Scholar]
  2. Ettinger B., Genant H. K., Cann C. E. Postmenopausal bone loss is prevented by treatment with low-dosage estrogen with calcium. Ann Intern Med. 1987 Jan;106(1):40–45. doi: 10.7326/0003-4819-106-1-40. [DOI] [PubMed] [Google Scholar]
  3. Exner G. U., Prader A., Elsasser U., Rüegsegger P., Anliker M. Bone densitometry using computed tomography. Part I: selective determination of trabecular bone density and other bone mineral parameters. Normal values in children and adults. Br J Radiol. 1979 Jan;52(613):14–23. doi: 10.1259/0007-1285-52-613-14. [DOI] [PubMed] [Google Scholar]
  4. Genant H. K., Cann C. E., Ettinger B., Gordan G. S. Quantitative computed tomography of vertebral spongiosa: a sensitive method for detecting early bone loss after oophorectomy. Ann Intern Med. 1982 Nov;97(5):699–705. doi: 10.7326/0003-4819-97-5-699. [DOI] [PubMed] [Google Scholar]
  5. Heaney R. P., Recker R. R., Saville P. D. Menopausal changes in calcium balance performance. J Lab Clin Med. 1978 Dec;92(6):953–963. [PubMed] [Google Scholar]
  6. Horsman A., Gallagher J. C., Simpson M., Nordin B. E. Prospective trial of oestrogen and calcium in postmenopausal women. Br Med J. 1977 Sep 24;2(6090):789–792. doi: 10.1136/bmj.2.6090.789. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Matković V., Kostial K., Simonović I., Buzina R., Brodarec A., Nordin B. E. Bone status and fracture rates in two regions of Yugoslavia. Am J Clin Nutr. 1979 Mar;32(3):540–549. doi: 10.1093/ajcn/32.3.540. [DOI] [PubMed] [Google Scholar]
  8. Nilas L., Christiansen C., Rødbro P. Calcium supplementation and postmenopausal bone loss. Br Med J (Clin Res Ed) 1984 Oct 27;289(6452):1103–1106. doi: 10.1136/bmj.289.6452.1103. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Recker R. R., Heaney R. P. The effect of milk supplements on calcium metabolism, bone metabolism and calcium balance. Am J Clin Nutr. 1985 Feb;41(2):254–263. doi: 10.1093/ajcn/41.2.254. [DOI] [PubMed] [Google Scholar]
  10. Recker R. R., Saville P. D., Heaney R. P. Effect of estrogens and calcium carbonate on bone loss in postmenopausal women. Ann Intern Med. 1977 Dec;87(6):649–655. doi: 10.7326/0003-4819-87-6-649. [DOI] [PubMed] [Google Scholar]
  11. Riggs B. L., Wahner H. W., Melton L. J., 3rd, Richelson L. S., Judd H. L., O'Fallon W. M. Dietary calcium intake and rates of bone loss in women. J Clin Invest. 1987 Oct;80(4):979–982. doi: 10.1172/JCI113191. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Riis B., Thomsen K., Christiansen C. Does calcium supplementation prevent postmenopausal bone loss? A double-blind, controlled clinical study. N Engl J Med. 1987 Jan 22;316(4):173–177. doi: 10.1056/NEJM198701223160401. [DOI] [PubMed] [Google Scholar]
  13. Sandler R. B., Slemenda C. W., LaPorte R. E., Cauley J. A., Schramm M. M., Barresi M. L., Kriska A. M. Postmenopausal bone density and milk consumption in childhood and adolescence. Am J Clin Nutr. 1985 Aug;42(2):270–274. doi: 10.1093/ajcn/42.2.270. [DOI] [PubMed] [Google Scholar]
  14. Simonen O., Laitinen O. Does fluoridation of drinking-water prevent bone fragility and osteoporosis? Lancet. 1985 Aug 24;2(8452):432–434. doi: 10.1016/s0140-6736(85)92748-5. [DOI] [PubMed] [Google Scholar]
  15. Spinks T. J. Effect of size and composition of the body on absolute measurement of calcium in vivo. Phys Med Biol. 1979 Sep;24(5):976–987. doi: 10.1088/0031-9155/24/5/010. [DOI] [PubMed] [Google Scholar]
  16. Stevenson J. C., Banks L. M., Spinks T. J., Freemantle C., MacIntyre I., Hesp R., Lane G., Endacott J. A., Padwick M., Whitehead M. I. Regional and total skeletal measurements in the early postmenopause. J Clin Invest. 1987 Jul;80(1):258–262. doi: 10.1172/JCI113056. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Stevenson J. C., Whitehead M. I. Postmenopausal osteoporosis. 1982 Aug 28-Sep 4Br Med J (Clin Res Ed) 285(6342):585–588. doi: 10.1136/bmj.285.6342.585. [DOI] [PMC free article] [PubMed] [Google Scholar]

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