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. 1984 Feb;25(2):187–190. doi: 10.1128/aac.25.2.187

Plasmid-mediated tetracycline resistance in Haemophilus ducreyi.

W L Albritton, I W Maclean, L A Slaney, A R Ronald, H G Deneer
PMCID: PMC185471  PMID: 6324665

Abstract

Clinical isolates of Haemophilus ducreyi were shown to be resistant to tetracycline. Resistance was associated in some strains with a 30-megadalton plasmid capable of transferring resistance in conjugative matings with other strains of H. ducreyi and other species of Haemophilus. Restriction endonuclease digestion patterns suggest a relationship between H. ducreyi plasmids and other tetracycline resistance plasmids in Haemophilus. The presence of plasmid-mediated resistance to the tetracyclines limits the use of these agents for the treatment of chancroid.

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Selected References

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