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. 1994 Feb;62(2):764–767. doi: 10.1128/iai.62.2.764-767.1994

Human secretory immunoglobulin A anti-Entamoeba histolytica antibodies inhibit adherence of amebae to MDCK cells.

J C Carrero 1, M Y Díaz 1, M Viveros 1, B Espinoza 1, E Acosta 1, L Ortiz-Ortiz 1
PMCID: PMC186177  PMID: 8300242

Abstract

The presence of secretory immunoglobulin A (IgA) anti-Entamoeba histolytica antibodies in the saliva of patients with intestinal amebiasis was demonstrated by immunoblot assay, and the capacity of these antibodies to inhibit amebic adherence to a monolayer of MDCK cells was analyzed. Inhibition was due to IgA antiamebic antibodies and in part to anti-Gal-binding-lectin antibodies, as demonstrated by absorption experiments with total amebic extract and with the fraction of Gal-binding lectin. These results emphasize the relevance of secretory IgA antibodies in the phenomenon of E. histolytica adherence to epithelial cells.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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