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Canadian Medical Association Journal logoLink to Canadian Medical Association Journal
. 1976 Dec 4;115(11):1096–1099.

Localisation du site de l'infection urinaire chez l'enfant par la recherche de bactéries recouvertes d'anticorps

Localization of the site of urinary infection in children by an investigation of antibody-covered bacteria

S Montplaisir, P P Côté, B Martineau, A J Roche, J G Mongeau, P Robitaille
PMCID: PMC1878893  PMID: 793701

Abstract

The demonstration by immuno-fluorescence of antibodies on the surface of urinary bacteria, a new method of determining the site of a urinary tract infection, was found to be as valuable in children as it is in adults. A clear correlation exists between a positive test result and renal parenchymal infection on one hand, and a negative result and lower urinary tract infection on the other. Moreover, immunoglobulins were still detectable in original positive urine samples that had been standing at 4degrees C for 7 weeks. The constant finding of IgA on bacteria suggests a particular synthesis for this class of immunoglobulin. A pathophysiologic role for complement would appear to be excluded by the facts that the serum concentrations of C3 were normal and that C3 was invariably absent from the bacterial surface.

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Selected References

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