Abstract
In the first 4 months of 1974, 140 gauze pad samples of sewage collected in the Ottawa area were analysed by the BS-C-1 cell system for the presence of viruses pathogenic for humans. Viruses were isolated from 111 (79%) of the samples. Of the 72 (65%) isolates identified by serology and electron microscopic examination, 56 (78%) were reoviruses and 16 (22%), enteroviruses. The enterovirus isolates included one coxsackievirus B4, one vaccine strain of poliovirus type 3, nine vaccine strains of poliovirus type 1 and five strains of poliovirus type 1 that proved by serodifferentiation and temperature marker tests to be different from vaccine strains. The fact that these strains were present in the community sewage in readily detectable concentrations at a time when immunity against polioviruses is declining in such communities is a cause for concern.
Full text
PDFSelected References
These references are in PubMed. This may not be the complete list of references from this article.
- Berg G. Removal of viruses from sewage, effluents, and waters. I. A review. Bull World Health Organ. 1973;49(5):451–460. [PMC free article] [PubMed] [Google Scholar]
- DANE D. S., DICK G. W., BRIGGS M., NELSON R., McALISTER J., CONNOLLY J. H., McKEOWN F., FIELD C. M. Vaccination against poliomyelitis with live virus vaccines. 8. Changes in Sabin type I oral vaccine virus after multiplication in the intestinal tract. Br Med J. 1961 Jul 29;2(5247):269–271. doi: 10.1136/bmj.2.5247.269. [DOI] [PMC free article] [PubMed] [Google Scholar]
- FRIEDMAN R. M., KIRSCHSTEIN R. L., BORMAN G. S., ROBBINS F. Characteristics of Sabin type I polivirus after gastrointestinal passage in newborn infants. I. Monkey neurovirulence and temperature marker findings. Am J Hyg. 1962 Sep;76:137–143. doi: 10.1093/oxfordjournals.aje.a120268. [DOI] [PubMed] [Google Scholar]
- Furesz J., Armstrong R. E. Further studies on the kinetic serum-neutralization (McBride) test for polioviruses. Can J Microbiol. 1967 Sep;13(9):1223–1233. doi: 10.1139/m67-167. [DOI] [PubMed] [Google Scholar]
- Furesz J., Armstrong R. E., Moreau P., Yarosh W., Nagler F. P. Antigenic studies on Sabin types 1 & 3 poliovaccine virus during 1 to 7 passages in the human intestinal tract. Am J Epidemiol. 1966 May;83(3):501–508. doi: 10.1093/oxfordjournals.aje.a120601. [DOI] [PubMed] [Google Scholar]
- GELFAND H. M., LeBLANC D. R., POTASH L., FOX J. P. Studies onthe development of natural immunity to poliomyelitis in Louisiana. IV. Natural infections with polioviruses following immunization with a formalin-inactivated vaccine. Am J Hyg. 1959 Nov;70:312–327. doi: 10.1093/oxfordjournals.aje.a120080. [DOI] [PubMed] [Google Scholar]
- Grew N., Gohd R. S., Arguedas J., Kato J. I. Enteroviruses in rural families and their domestic animals. Am J Epidemiol. 1970 May;91(5):518–526. doi: 10.1093/oxfordjournals.aje.a121162. [DOI] [PubMed] [Google Scholar]
- HOPPS H. E., BERNHEIM B. C., NISALAK A., TJIO J. H., SMADEL J. E. BIOLOGIC CHARACTERISTICS OF A CONTINUOUS KIDNEY CELL LINE DERIVED FROM THE AFRICAN GREEN MONKEY. J Immunol. 1963 Sep;91:416–424. [PubMed] [Google Scholar]
- HSIUNG G. D., MELNICK J. L. Effect of sodium bicarbonate concentration on plaque formation of virulent and attenuated polioviruses. J Immunol. 1958 Apr;80(4):282–293. [PubMed] [Google Scholar]
- Hawley H. B., Morin D. P., Geraghty M. E., Tomkow J., Phillips C. A. Coxsackievirus B epidemic at a Boy's Summer Camp. Isolation of virus from swimming water. JAMA. 1973 Oct 1;226(1):33–36. [PubMed] [Google Scholar]
- Horstmann D. M., Emmons J., Gimpel L., Subrahmanyan T., Riordan J. T. Enterovirus surveillance following a community-wide oral poliovirus vaccination program: a seven-year study. Am J Epidemiol. 1973 Mar;97(3):173–186. doi: 10.1093/oxfordjournals.aje.a121498. [DOI] [PubMed] [Google Scholar]
- LWOFF A., LWOFF M. Remarques sur quelques caractères du développment du virus de la poliomyélite. C R Hebd Seances Acad Sci. 1959 Mar 16;248(11):1725–1727. [PubMed] [Google Scholar]
- Lund E., Hedström C. E., Strannegård O. A comparison between virus isolations from sewage and from fecal specimens from patients. Am J Epidemiol. 1966 Sep;84(2):282–286. doi: 10.1093/oxfordjournals.aje.a120641. [DOI] [PubMed] [Google Scholar]
- MacLeod D. R., Ing W. K., Belcourt R. J., Pearson E. W., Bell J. S. Antibody status to poliomyelitis, measles, rubella, diphtheria and tetanus, Ontario, 1969-70: deficiencies discovered and remedies required. Can Med Assoc J. 1975 Oct 4;113(7):619–623. [PMC free article] [PubMed] [Google Scholar]
- Mack W. N., Lu Y. S., Coohon D. B. Isolation of poliomyelitis virus from a contaminated well. Health Serv Rep. 1972 Mar;87(3):271–274. [PMC free article] [PubMed] [Google Scholar]
- McBRIDE W. D. Antigenic analysis of polioviruses by kinetic studies of serum neutralization. Virology. 1959 Jan;7(1):45–58. doi: 10.1016/0042-6822(59)90176-x. [DOI] [PubMed] [Google Scholar]
- Melnick J. L., Burkhardt M., Taber L. H., Erckman P. N. Developing gap in immunity to poliomyelitis in an urban area. JAMA. 1969 Aug 25;209(8):1181–1185. [PubMed] [Google Scholar]
- Mortimer P. P., Cunningham P. Sero-immunity to poliovirus in children and young women: England 1972-4. J Hyg (Lond) 1975 Apr;74(2):283–287. doi: 10.1017/s0022172400024359. [DOI] [PMC free article] [PubMed] [Google Scholar]
- NAKANO J. H., GELFAND H. M., COLE J. T. THE USE OF A MODIFIED WECKER TECHNIQUE FOR SERODIFFERENTIATION OF TYPE 1 POLIOVIRUSES RELATED AND UNRELATED TO SABIN'S VACCINE STRAIN. II. ANTIGENIC SEGREGATION OF ISOLATES FROM SPECIMENS COLLECTED IN FIELD STUDIES. Am J Hyg. 1963 Sep;78:214–226. doi: 10.1093/oxfordjournals.aje.a120339. [DOI] [PubMed] [Google Scholar]
- Oberhofer T. R., Brown G. C., Monto A. S. Seroimmunity to poliomyelitis in an American community. Am J Epidemiol. 1975 Apr;101(4):333–339. doi: 10.1093/oxfordjournals.aje.a112101. [DOI] [PubMed] [Google Scholar]
- PAVILANIS V., LUSSIER G., FOLEY A. R., CHARBONNEAU J. H., DIFRANCO E., DUBREUIL R. A STUDY OF SABIN TYPE 1 ORAL VACCINE VIRUS DURING FIVE HUMAN PASSAGES. Rev Can Biol. 1964 Sep;23:265–276. [PubMed] [Google Scholar]
- RHODES A. J., CLARK E. M., KNOWLES D. S., SHIMADA F., GOODFELLOW A. M., RITCHIE R. C., DONOHUE W. L. Poliomyelitis virus in urban sewage; an examination for its presence over a period of 12 months. Can J Public Health. 1950 Jun;41(6):248–254. [PubMed] [Google Scholar]
- Subrahmanyan T. P., Lesiak J. M., Appleton F., Labzoffsky N. A. Paralytic poliomyelitis in Ontario: laboratory studies of two recent cases. Bull World Health Organ. 1973;49(3):245–250. [PMC free article] [PubMed] [Google Scholar]
- Wilterdink J. B., Weiland H. T., Verlinde J. D. A longitudinal study on the significance of examination of sewage for the presence of poliovirus in the population. Arch Gesamte Virusforsch. 1970;32(1):82–90. doi: 10.1007/BF01241523. [DOI] [PubMed] [Google Scholar]
- Zdrazílek J., Jadrnícková N., Jandásek L., Kasová V., Uvízl M., Valhrach J. Presence of poliovirus and other enteroviruses in sewage. A survey in Czechoslovakia, 1969-72. Bull World Health Organ. 1974;50(6):562–563. [PMC free article] [PubMed] [Google Scholar]