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The American Journal of Pathology logoLink to The American Journal of Pathology
. 1989 Mar;134(3):627–631.

Induction of a mixed ductal-squamous-islet cell carcinoma in a rat treated with a tobacco-specific carcinogen.

P M Pour 1, A Rivenson 1
PMCID: PMC1879513  PMID: 2538058

Abstract

Treatment of rats with tobacco-specific nitrosamines resulted in the induction of pancreatic acinar cell and ductal cell neoplasms. One of these tumors had a mixed ductal-squamous-islet cell components, the electron microscopic and immunohistochemical patterns of which are described. This is the first report of such a pancreatic mixed cell neoplasm.

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Selected References

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