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. 1992 Feb;36(2):277–282. doi: 10.1128/aac.36.2.277

In vitro antibiotic susceptibilities of Neisseria gonorrhoeae isolates in the Philippines.

T E Clendennen 3rd 1, C S Hames 1, E S Kees 1, F C Price 1, W J Rueppel 1, A B Andrada 1, G E Espinosa 1, G Kabrerra 1, F S Wignall 1
PMCID: PMC188352  PMID: 1605592

Abstract

Antibiotic susceptibility surveillance testing was performed on clinical isolates of Neisseria gonorrhoeae collected in September 1989 in the Philippines. beta-Lactamase was produced by 77 (55%) of 140 isolates. In vitro MIC testing revealed significant resistance to penicillin (MIC for 90% of isolates [MIC90], greater than 64 micrograms/ml), tetracycline (MIC90, 4 micrograms/ml), and cefmetazole (MIC90, 8 micrograms/ml). Spectinomycin resistance was rare (10 of 117), but the MIC90 was 32 micrograms/ml. Isolates were susceptible to fluoroquinolones and cephalosporins at the time of this survey, as evidenced by the MIC90s of ciprofloxacin (0.25 microgram/ml), norfloxacin (2.0 micrograms/ml), ofloxacin (0.625 microgram/ml), cefpodoxime (2.0 micrograms/ml), cefotaxime (1.0 microgram/ml), ceftazidime (0.25 microgram/ml), ceftizoxime (0.25 microgram/ml), and ceftriaxone (0.06 microgram/ml). To date, ceftriaxone resistance has not emerged, despite the widespread use of this antibiotic in the Philippines.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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