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. 1997 Oct;41(4):422–424. doi: 10.1136/gut.41.4.422

The aging oesophagus

J TACK 1, G VANTRAPPEN 1
PMCID: PMC1891523  PMID: 9391234

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Adamek R. J., Wegener M., Wienbeck M., Gielen B. Long-term esophageal manometry in healthy subjects. Evaluation of normal values and influence of age. Dig Dis Sci. 1994 Oct;39(10):2069–2073. doi: 10.1007/BF02090352. [DOI] [PubMed] [Google Scholar]
  2. Brody E. M., Kleban M. H., Moles E. What older people do about their day-to-day mental and physical health symptoms. J Am Geriatr Soc. 1983 Aug;31(8):489–498. doi: 10.1111/j.1532-5415.1983.tb05124.x. [DOI] [PubMed] [Google Scholar]
  3. Cameron A. J., Lomboy C. T. Barrett's esophagus: age, prevalence, and extent of columnar epithelium. Gastroenterology. 1992 Oct;103(4):1241–1245. doi: 10.1016/0016-5085(92)91510-b. [DOI] [PubMed] [Google Scholar]
  4. Champion G., Richter J. E., Vaezi M. F., Singh S., Alexander R. Duodenogastroesophageal reflux: relationship to pH and importance in Barrett's esophagus. Gastroenterology. 1994 Sep;107(3):747–754. doi: 10.1016/0016-5085(94)90123-6. [DOI] [PubMed] [Google Scholar]
  5. Clark G. W., Smyrk T. C., Burdiles P., Hoeft S. F., Peters J. H., Kiyabu M., Hinder R. A., Bremner C. G., DeMeester T. R. Is Barrett's metaplasia the source of adenocarcinomas of the cardia? Arch Surg. 1994 Jun;129(6):609–614. doi: 10.1001/archsurg.1994.01420300051007. [DOI] [PubMed] [Google Scholar]
  6. Collen M. J., Abdulian J. D., Chen Y. K. Age does not affect basal gastric acid secretion in normal subjects or in patients with acid-peptic disease. Am J Gastroenterol. 1994 May;89(5):712–716. [PubMed] [Google Scholar]
  7. Collen M. J., Abdulian J. D., Chen Y. K. Gastroesophageal reflux disease in the elderly: more severe disease that requires aggressive therapy. Am J Gastroenterol. 1995 Jul;90(7):1053–1057. [PubMed] [Google Scholar]
  8. Croghan J. E., Burke E. M., Caplan S., Denman S. Pilot study of 12-month outcomes of nursing home patients with aspiration on videofluoroscopy. Dysphagia. 1994 Summer;9(3):141–146. doi: 10.1007/BF00341256. [DOI] [PubMed] [Google Scholar]
  9. Dodds W. J., Dent J., Hogan W. J., Helm J. F., Hauser R., Patel G. K., Egide M. S. Mechanisms of gastroesophageal reflux in patients with reflux esophagitis. N Engl J Med. 1982 Dec 16;307(25):1547–1552. doi: 10.1056/NEJM198212163072503. [DOI] [PubMed] [Google Scholar]
  10. Eckardt V. F., LeCompte P. M. Esophageal ganglia and smooth muscle in the elderly. Am J Dig Dis. 1978 May;23(5):443–448. doi: 10.1007/BF01072928. [DOI] [PubMed] [Google Scholar]
  11. Ekberg O., Feinberg M. J. Altered swallowing function in elderly patients without dysphagia: radiologic findings in 56 cases. AJR Am J Roentgenol. 1991 Jun;156(6):1181–1184. doi: 10.2214/ajr.156.6.2028863. [DOI] [PubMed] [Google Scholar]
  12. Ertan A., Zimmerman M., Younes M. Esophageal adenocarcinoma associated with Barrett's esophagus: long-term management with laser ablation. Am J Gastroenterol. 1995 Dec;90(12):2201–2203. [PubMed] [Google Scholar]
  13. Fass R., Sampliner R. E., Mackel C., McGee D., Rappaport W. Age- and gender-related differences in 24-hour esophageal pH monitoring of normal subjects. Dig Dis Sci. 1993 Oct;38(10):1926–1928. doi: 10.1007/BF01296120. [DOI] [PubMed] [Google Scholar]
  14. Fulp S. R., Dalton C. B., Castell J. A., Castell D. O. Aging-related alterations in human upper esophageal sphincter function. Am J Gastroenterol. 1990 Dec;85(12):1569–1572. [PubMed] [Google Scholar]
  15. GROSSMAN M. I., KIRSNER J. B., GILLESPIE I. E. BASAL AND HISTALOG-STIMULATED GASTRIC SECRETION IN CONTROL SUBJECTS AND IN PATIENTS WITH PEPTIC ULCER OR GASTRIC CANCER. Gastroenterology. 1963 Jul;45:14–26. [PubMed] [Google Scholar]
  16. Gainsborough N., Maskrey V. L., Nelson M. L., Keating J., Sherwood R. A., Jackson S. H., Swift C. G. The association of age with gastric emptying. Age Ageing. 1993 Jan;22(1):37–40. doi: 10.1093/ageing/22.1.37. [DOI] [PubMed] [Google Scholar]
  17. Ghosh S., Heading R. C., Palmer K. R. Achalasia of the oesophagus in elderly patients responds poorly to conservative therapy. Age Ageing. 1994 Jul;23(4):280–282. doi: 10.1093/ageing/23.4.280. [DOI] [PubMed] [Google Scholar]
  18. Goldschmid S., Nord H. J. Endoscopic diagnosis and treatment of esophageal cancer. Gastrointest Endosc Clin N Am. 1994 Oct;4(4):827–850. [PubMed] [Google Scholar]
  19. Grishaw E. K., Ott D. J., Frederick M. G., Gelfand D. W., Chen M. Y. Functional abnormalities of the esophagus: a prospective analysis of radiographic findings relative to age and symptoms. AJR Am J Roentgenol. 1996 Sep;167(3):719–723. doi: 10.2214/ajr.167.3.8751689. [DOI] [PubMed] [Google Scholar]
  20. Hollis J. B., Castell D. O. Esophageal function in elderly man. A new look at "presbyesophagus". Ann Intern Med. 1974 Mar;80(3):371–374. doi: 10.7326/0003-4819-80-3-371. [DOI] [PubMed] [Google Scholar]
  21. James O. F., Parry-Billings K. S. Comparison of omeprazole and histamine H2-receptor antagonists in the treatment of elderly and young patients with reflux oesophagitis. Age Ageing. 1994 Mar;23(2):121–126. doi: 10.1093/ageing/23.2.121. [DOI] [PubMed] [Google Scholar]
  22. Khan T. A., Shragge B. W., Crispin J. S., Lind J. F. Esophageal motility in the elderly. Am J Dig Dis. 1977 Dec;22(12):1049–1054. doi: 10.1007/BF01072855. [DOI] [PubMed] [Google Scholar]
  23. Kruse-Andersen S., Wallin L., Madsen T. The influence of age on esophageal acid defense mechanisms and spontaneous acid gastroesophageal reflux. Am J Gastroenterol. 1988 Jun;83(6):637–639. [PubMed] [Google Scholar]
  24. Lickiss J. N. Palliative care and melanoma: the care of the patient with progressive disease. World J Surg. 1992 Mar-Apr;16(2):282–286. doi: 10.1007/BF02071533. [DOI] [PubMed] [Google Scholar]
  25. Lindgren S., Janzon L. Prevalence of swallowing complaints and clinical findings among 50-79-year-old men and women in an urban population. Dysphagia. 1991;6(4):187–192. doi: 10.1007/BF02493524. [DOI] [PubMed] [Google Scholar]
  26. Meshkinpour H., Haghighat P., Dutton C. Clinical spectrum of esophageal aperistalsis in the elderly. Am J Gastroenterol. 1994 Sep;89(9):1480–1483. [PubMed] [Google Scholar]
  27. Mold J. W., Reed L. E., Davis A. B., Allen M. L., Decktor D. L., Robinson M. Prevalence of gastroesophageal reflux in elderly patients in a primary care setting. Am J Gastroenterol. 1991 Aug;86(8):965–970. [PubMed] [Google Scholar]
  28. Overholt B. F., Panjehpour M. Barrett's esophagus: photodynamic therapy for ablation of dysplasia, reduction of specialized mucosa, and treatment of superficial esophageal cancer. Gastrointest Endosc. 1995 Jul;42(1):64–70. doi: 10.1016/s0016-5107(95)70246-6. [DOI] [PubMed] [Google Scholar]
  29. Pasricha P. J., Rai R., Ravich W. J., Hendrix T. R., Kalloo A. N. Botulinum toxin for achalasia: long-term outcome and predictors of response. Gastroenterology. 1996 May;110(5):1410–1415. doi: 10.1053/gast.1996.v110.pm8613045. [DOI] [PubMed] [Google Scholar]
  30. Pera M., Cameron A. J., Trastek V. F., Carpenter H. A., Zinsmeister A. R. Increasing incidence of adenocarcinoma of the esophagus and esophagogastric junction. Gastroenterology. 1993 Feb;104(2):510–513. doi: 10.1016/0016-5085(93)90420-h. [DOI] [PubMed] [Google Scholar]
  31. Ren J., Shaker R., Kusano M., Podvrsan B., Metwally N., Dua K. S., Sui Z. Effect of aging on the secondary esophageal peristalsis: presbyesophagus revisited. Am J Physiol. 1995 May;268(5 Pt 1):G772–G779. doi: 10.1152/ajpgi.1995.268.5.G772. [DOI] [PubMed] [Google Scholar]
  32. Richter J. E., Bradley L. A., DeMeester T. R., Wu W. C. Normal 24-hr ambulatory esophageal pH values. Influence of study center, pH electrode, age, and gender. Dig Dis Sci. 1992 Jun;37(6):849–856. doi: 10.1007/BF01300382. [DOI] [PubMed] [Google Scholar]
  33. Richter J. E., Wu W. C., Johns D. N., Blackwell J. N., Nelson J. L., 3rd, Castell J. A., Castell D. O. Esophageal manometry in 95 healthy adult volunteers. Variability of pressures with age and frequency of "abnormal" contractions. Dig Dis Sci. 1987 Jun;32(6):583–592. doi: 10.1007/BF01296157. [DOI] [PubMed] [Google Scholar]
  34. Räihä I., Hietanen E., Sourander L. Symptoms of gastro-oesophageal reflux disease in elderly people. Age Ageing. 1991 Sep;20(5):365–370. doi: 10.1093/ageing/20.5.365. [DOI] [PubMed] [Google Scholar]
  35. SOERGEL K. H., ZBORALSKE F. F., AMBERG J. R. PRESBYESOPHAGUS: ESOPHAGEAL MOTILITY IN NONAGENARIANS. J Clin Invest. 1964 Jul;43:1472–1479. doi: 10.1172/JCI105023. [DOI] [PMC free article] [PubMed] [Google Scholar]
  36. Schneider I., Thumfart W. F., Pototschnig C., Eckel H. E. Treatment of dysfunction of the cricopharyngeal muscle with botulinum A toxin: introduction of a new, noninvasive method. Ann Otol Rhinol Laryngol. 1994 Jan;103(1):31–35. doi: 10.1177/000348949410300105. [DOI] [PubMed] [Google Scholar]
  37. Schoeman M. N., Tippett M. D., Akkermans L. M., Dent J., Holloway R. H. Mechanisms of gastroesophageal reflux in ambulant healthy human subjects. Gastroenterology. 1995 Jan;108(1):83–91. doi: 10.1016/0016-5085(95)90011-x. [DOI] [PubMed] [Google Scholar]
  38. Shaker R., Ren J., Zamir Z., Sarna A., Liu J., Sui Z. Effect of aging, position, and temperature on the threshold volume triggering pharyngeal swallows. Gastroenterology. 1994 Aug;107(2):396–402. doi: 10.1016/0016-5085(94)90164-3. [DOI] [PubMed] [Google Scholar]
  39. Siebens H., Trupe E., Siebens A., Cook F., Anshen S., Hanauer R., Oster G. Correlates and consequences of eating dependency in institutionalized elderly. J Am Geriatr Soc. 1986 Mar;34(3):192–198. doi: 10.1111/j.1532-5415.1986.tb04202.x. [DOI] [PubMed] [Google Scholar]
  40. Smout A. J., Breedijk M., van der Zouw C., Akkermans L. M. Physiological gastroesophageal reflux and esophageal motor activity studied with a new system for 24-hour recording and automated analysis. Dig Dis Sci. 1989 Mar;34(3):372–378. doi: 10.1007/BF01536258. [DOI] [PubMed] [Google Scholar]
  41. Spechler S. J., Zeroogian J. M., Antonioli D. A., Wang H. H., Goyal R. K. Prevalence of metaplasia at the gastro-oesophageal junction. Lancet. 1994 Dec 3;344(8936):1533–1536. doi: 10.1016/s0140-6736(94)90349-2. [DOI] [PubMed] [Google Scholar]
  42. Spence R. A., Collins B. J., Parks T. G., Love A. H. Does age influence normal gastro-oesophageal reflux? Gut. 1985 Aug;26(8):799–801. doi: 10.1136/gut.26.8.799. [DOI] [PMC free article] [PubMed] [Google Scholar]
  43. Wilson J. A., Pryde A., Macintyre C. C., Maran A. G., Heading R. C. The effects of age, sex, and smoking on normal pharyngoesophageal motility. Am J Gastroenterol. 1990 Jun;85(6):686–691. [PubMed] [Google Scholar]

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