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. 1964 Mar;44(3):383–400.

Electron Microscopy of Renal Coagulative Necrosis Due to dl-Serine, with Special Reference to Mitochondrial Pyknosis

Max Wachstein, Martin Besen
PMCID: PMC1907011  PMID: 14126661

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ASHFORD T. P., PORTER K. R. Cytoplasmic components in hepatic cell lysosomes. J Cell Biol. 1962 Jan;12:198–202. doi: 10.1083/jcb.12.1.198. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. ASHWORTH C. T., LUIBEL F. J., SANDERS E., ARNOLD N. Hepatic cell degeneration. Correlation of fine structural with chemical and histochemical changes in hepatic cell injury produced by carbon tetrachloride in rats. Arch Pathol. 1963 Feb;75:212–225. [PubMed] [Google Scholar]
  3. BASSI M., BERNELLI-ZAZZERA A., CASSI E. Electron microscopy of rat liver cells in hypoxia. J Pathol Bacteriol. 1960 Jan;79:179–183. doi: 10.1002/path.1700790124. [DOI] [PubMed] [Google Scholar]
  4. BASSI M., BERNELLI-ZAZZERA A. Vacuolar degeneration of rat liver cells by electron microscopy. Nature. 1957 Feb 2;179(4553):256–257. doi: 10.1038/179256a0. [DOI] [PubMed] [Google Scholar]
  5. BEARCROFT W. G. Electron-microscope studies on the livers of yellow-fever-infected African monkeys. J Pathol Bacteriol. 1962 Jan;83:59–64. doi: 10.1002/path.1700830108. [DOI] [PubMed] [Google Scholar]
  6. BIAVA C. G., DYRDA I., GENEST I., BENCOSME S. A. Kaliopenic nephropathy. A correlated light and electron microscopic study. Lab Invest. 1963 Apr;12:443–453. [PubMed] [Google Scholar]
  7. BREWER D. B., EGUREN L. M. The fine structure of protein droplets in the proximal convoluted tubule of the mouse kidney. J Pathol Bacteriol. 1962 Jan;83:107–116. doi: 10.1002/path.1700830113. [DOI] [PubMed] [Google Scholar]
  8. CAULFIELD J. B., TRUMP B. F. Correlation of ultrastructure with function in the rat kidney. Am J Pathol. 1962 Feb;40:199–218. [PMC free article] [PubMed] [Google Scholar]
  9. CAULFIELD J., KLIONSKY B. Myocardial ischemia and early infarction: an electron microscopic study. Am J Pathol. 1959 May-Jun;35(3):489–523. [PMC free article] [PubMed] [Google Scholar]
  10. EMMELOT P., BENEDETTI E. L. Changes in the fine structure of rat liver cells brought about by dimethylnitrosamine. J Biophys Biochem Cytol. 1960 Apr;7:393–396. doi: 10.1083/jcb.7.2.393. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. GANSLER H., ROUILLER C. Modifications physiologiques et pathologiques du chondriome; etude au microscope électronique. Schweiz Z Pathol Bakteriol. 1956;19(2):217–243. [PubMed] [Google Scholar]
  12. HOLMBERG B. On the permeability to lissamine green and other dyes in the course of cell injury and cell death. Exp Cell Res. 1961 Jan;22:406–414. doi: 10.1016/0014-4827(61)90118-5. [DOI] [PubMed] [Google Scholar]
  13. HRUBAN Z., SPARGO B., SWIFT H., WISSLER R. W., KLEINFELD R. G. Focal cytoplasmic degradation. Am J Pathol. 1963 Jun;42:657–683. [PMC free article] [PubMed] [Google Scholar]
  14. HRUBAN Z., SWIFT H., WISSLER R. W. Analog-induced inclusions in pancreatic acinar cells. J Ultrastruct Res. 1962 Oct;7:273–285. doi: 10.1016/s0022-5320(62)90023-0. [DOI] [PubMed] [Google Scholar]
  15. LATTA H., BENCOSME S. A., KNIGGE K. M., MADDEN S. C. Extracellular compartments in renal tubules associated with polyuria from glucose inhibition. Lab Invest. 1962 Aug;11:569–579. [PubMed] [Google Scholar]
  16. MANNWEILER K., BERNHARD W. Recherches ultrastructurales sur une tumeur rénale expérimentale du hamster. J Ultrastruct Res. 1957 Dec;1(2):158–169. doi: 10.1016/s0022-5320(57)80004-5. [DOI] [PubMed] [Google Scholar]
  17. MAUNSBACH A. B., MADDEN S. C., LATTA H. Variations in fine structure of renal tubular epithelium under different conditions of fixation. J Ultrastruct Res. 1962 Jun;6:511–530. doi: 10.1016/s0022-5320(62)80006-9. [DOI] [PubMed] [Google Scholar]
  18. MILLER F. Hemoglobin absorption by the cells of the proximal convoluted tubule in mouse kidney. J Biophys Biochem Cytol. 1960 Dec;8:689–718. doi: 10.1083/jcb.8.3.689. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Morehead R. P., Fishman W. H., Artom C. Renal Injury in the Rat Following the Administration of Serine by Stomach Tube. Am J Pathol. 1945 Jul;21(4):803–815. [PMC free article] [PubMed] [Google Scholar]
  20. Morehead R. P., Fishman W. H., Artom C. The Nephrotoxic Action of DL-Serine as Related to Certain Dietary Factors. Am J Pathol. 1946 Mar;22(2):385–393. [PMC free article] [PubMed] [Google Scholar]
  21. NOVIKOFF A. B., ESSNER E. Cytolysomes and mitochondrial degeneration. J Cell Biol. 1962 Oct;15:140–146. doi: 10.1083/jcb.15.1.140. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. OUDEA P. R. Anoxic changes of liver cells. Electron microscopic study after injection of colloidal mercury. Lab Invest. 1963 Mar;12:386–394. [PubMed] [Google Scholar]
  23. PORTER K. R., BRUNI C. An electron microscope study of the early effects of 3'-Me-DAB on rat liver cells. Cancer Res. 1959 Nov;19:997–1009. [PubMed] [Google Scholar]
  24. ROUILLER C. Contribution de la microscopie électronique à l'étude du foie normal et pathologique. Ann Anat Pathol (Paris) 1957 Oct-Dec;2(4):548–562. [PubMed] [Google Scholar]
  25. ROUILLER C., MODJTABAI A. La néphrose expérimentale du lapin; comparaison entre la microscopie optique et électronique. I. Les modifications des cellules à bordure striée. Ann Anat Pathol (Paris) 1958 Apr-Jun;3(2):223–250. [PubMed] [Google Scholar]
  26. ROUILLER C. Physiological and pathological changes in mitochondrial morphology. Int Rev Cytol. 1960;9:227–292. doi: 10.1016/s0074-7696(08)62748-5. [DOI] [PubMed] [Google Scholar]
  27. SMUCKLER E. A., ISERI O. A., BENDITT E. P. An intracellular defect in protein synthesis induced by carbon tetrachloride. J Exp Med. 1962 Jul 1;116:55–72. doi: 10.1084/jem.116.1.55. [DOI] [PMC free article] [PubMed] [Google Scholar]
  28. SVOBODA D. J., HIGGINSON J. ULTRASTRUCTURAL HEPATIC CHANGES IN RATS ON A NECROGENIC DIET. Am J Pathol. 1963 Sep;43:477–495. [PMC free article] [PubMed] [Google Scholar]
  29. SVOBODA D., NIELSON A., WERBER A., HIGGINSON J. An electron microscopic study of viral hepatitis in mice. Am J Pathol. 1962 Aug;41:205–224. [PMC free article] [PubMed] [Google Scholar]
  30. TRUMP B. F., GOLDBLATT P. J., STOWELL R. E. An electron microscopic study of early cytoplasmic alterations in hepatic parenchymal cells of mouse liver during necrosis in vitro (autolysis). Lab Invest. 1962 Nov;11:986–1015. [PubMed] [Google Scholar]
  31. TRUMP B. F., JANIGAN D. T. The pathogenesis of cytologic vacuolization in sucrose nephrosis. An electron microscopic and histochemical study. Lab Invest. 1962 May;11:395–411. [PubMed] [Google Scholar]
  32. WACHSTEIN M., MEISEL E., FALCON C. Enzymatic histochemistry in the experimentally damaged liver. Am J Pathol. 1962 Feb;40:219–241. [PMC free article] [PubMed] [Google Scholar]
  33. WILSON J. W., LEDUC E. H. Mitochondrial changes in the liver of essential fatty acid-deficient mice. J Cell Biol. 1963 Feb;16:281–296. doi: 10.1083/jcb.16.2.281. [DOI] [PMC free article] [PubMed] [Google Scholar]

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