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Canadian Medical Association Journal logoLink to Canadian Medical Association Journal
. 1967 Jun 24;96(25):1610–1614.

The Influence of Morphology on Prognosis in Acute Leukemia

R Hasselback, Marja Soots, John Curtis, G L Robertson, D H Cowan, G D Hart
PMCID: PMC1923070  PMID: 5229656

Abstract

The presence of definite cytoplasmic granulation in at least some of the malignant cells was used as the sole criterion to separate 156 patients with acute leukemia into two groups: 110 with myeloblastic (AML), and 46 with lymphoblastic or stem cell leukemia (ALL). The median survival from the onset of symptoms in patients with AML was 20 weeks, and those with ALL 37 weeks. The difference in survival in these two groups is much greater for patients under the age of 25 than for those over the age of 25.

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