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. 1960 Nov 5;83(19):979–986.

Sex Chromatin, Sex Chromosomes and Sex Anomalies *

Murray L Barr, David H Carr
PMCID: PMC1938900  PMID: 13687230

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BARR M. L., PLUNKETT E. R. Testicular dysgenesis affecting the seminiferous tubules principally, with chromatin-positive nuclei. Lancet. 1956 Oct 27;271(6948):853–856. doi: 10.1016/s0140-6736(56)91036-4. [DOI] [PubMed] [Google Scholar]
  2. BARR M. L. Sexual dimorphism in interphase nuclei. Am J Hum Genet. 1960 Mar;12:118–127. [PMC free article] [PubMed] [Google Scholar]
  3. BUNGE R. G., BRADBURY J. T. A 10-year-old boy with a positive sex chromatin test. J Urol. 1957 Dec;78(6):775–779. doi: 10.1016/S0022-5347(17)66501-7. [DOI] [PubMed] [Google Scholar]
  4. COURT BROWN W. M., JACOBS P. A., DOLL R. Interpretation of chromosome counts made on bone-marrow cells. Lancet. 1960 Jan 16;1(7116):160–163. doi: 10.1016/s0140-6736(60)90072-6. [DOI] [PubMed] [Google Scholar]
  5. FERGUSON-SMITH M. A. Chromation-positive Klinefelter's syndrome (primary microrchidism) in a mental-deficiency hospital. Lancet. 1958 May 3;1(7027):928–931. doi: 10.1016/s0140-6736(58)91684-2. [DOI] [PubMed] [Google Scholar]
  6. FERGUSON-SMITH M. A., JOHNSTON A. W., HANDMAKER S. D. Primary amentia and micro-orchidism associated with an XXXY sex-chromosome constitution. Lancet. 1960 Jul 23;2(7143):184–187. doi: 10.1016/s0140-6736(60)91329-5. [DOI] [PubMed] [Google Scholar]
  7. FERGUSON-SMITH M. A. The prepubertal testicular lesion in chromatin-positive Klinefelter's syndrome (primary micro-orchidism) as seen in mentally handicapped children. Lancet. 1959 Jan 31;1(7066):219–222. doi: 10.1016/s0140-6736(59)90049-2. [DOI] [PubMed] [Google Scholar]
  8. FORD C. E., JACOBS P. A., LAJTHA L. G. Human somatic chromosomes. Nature. 1958 Jun 7;181(4623):1565–1568. doi: 10.1038/1811565a0. [DOI] [PubMed] [Google Scholar]
  9. FORD C. E., JONES K. W., POLANI P. E., DE ALMEIDA J. C., BRIGGS J. H. A sex-chromosome anomaly in a case of gonadal dysgenesis (Turner's syndrome). Lancet. 1959 Apr 4;1(7075):711–713. doi: 10.1016/s0140-6736(59)91893-8. [DOI] [PubMed] [Google Scholar]
  10. FORD C. E., POLANI P. E., BRIGGS J. H., BISHOP P. M. A presumptive human XXY/XX mosaic. Nature. 1959 Apr 11;183(4667):1030–1032. doi: 10.1038/1831030a0. [DOI] [PubMed] [Google Scholar]
  11. FRACCARO M., KAIJSER K., LINDSTEN J. Somatic chromosome complement in continuously cultured cells of two individuals with gonadal dysgenesis. Ann Hum Genet. 1960 Apr;24:45–61. doi: 10.1111/j.1469-1809.1959.tb01714.x. [DOI] [PubMed] [Google Scholar]
  12. GRUMBACH M. M., BARR M. L. Cytologic tests of chromosomal sex in relation to sexual anomalies in man. Recent Prog Horm Res. 1958;14:255–334. [PubMed] [Google Scholar]
  13. HAMBLEN E. C., PALMA E., POSHYACHINDA D. The congenitally rudimentary gonad syndrome. Clin Obstet Gynecol. 1960 Mar;3:207–219. doi: 10.1097/00003081-196003000-00020. [DOI] [PubMed] [Google Scholar]
  14. HARNDEN D. G., ARMSTRONG C. N. The chromosomes of a true hermaphrodite. Br Med J. 1959 Dec 12;2(5162):1287–1288. doi: 10.1136/bmj.2.5162.1287. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. HARNDEN D. G., STEWART J. S. The chromosomes in a case of pure gonadal dysgenesis. Br Med J. 1959 Dec 12;2(5162):1285–1287. doi: 10.1136/bmj.2.5162.1285. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. HUNGERFORD D. A., DONNELLY A. J., NOWELL P. C., BECK S. The chromosome constitution of a human phenotypic intersex. Am J Hum Genet. 1959 Sep;11:215–236. [PMC free article] [PubMed] [Google Scholar]
  17. JACOBS P. A., BAIKIE A. G., BROWN W. M., MACGREGOR T. N., MACLEAN N., HARNDEN D. G. Evidence for the existence of the human "super female". Lancet. 1959 Sep 26;2(7100):423–425. doi: 10.1016/s0140-6736(59)90415-5. [DOI] [PubMed] [Google Scholar]
  18. JACOBS P. A., BAIKIE A. G., COURT BROWN W. M., STRONG J. A. The somatic chromosomes in mongolism. Lancet. 1959 Apr 4;1(7075):710–710. doi: 10.1016/s0140-6736(59)91892-6. [DOI] [PubMed] [Google Scholar]
  19. JACOBS P. A., HARNDEN D. G., COURT BROWN W. M., GOLDSTEIN J., CLOSE H. G., MACGREGOR T. N., MACLEAN N., STRONG J. A. Abnormalities involving the X chromosome in women. Lancet. 1960 Jun 4;1(7136):1213–1216. doi: 10.1016/s0140-6736(60)91097-7. [DOI] [PubMed] [Google Scholar]
  20. JACOBS P. A., STRONG J. A. A case of human intersexuality having a possible XXY sex-determining mechanism. Nature. 1959 Jan 31;183(4657):302–303. doi: 10.1038/183302a0. [DOI] [PubMed] [Google Scholar]
  21. MOORE K. L., BARR M. L. Nuclear morphology, according to sex, in human tissues. Acta Anat (Basel) 1954;21(3):197–208. doi: 10.1159/000140928. [DOI] [PubMed] [Google Scholar]
  22. MOORE K. L., BARR M. L. Smears from the oral mucosa in the detection of chromosomal sex. Lancet. 1955 Jul 9;269(6880):57–58. doi: 10.1016/s0140-6736(55)92161-9. [DOI] [PubMed] [Google Scholar]
  23. MOORE K. L., GRAHAM M. A., BARR M. L. The detection of chromosomal sex in hermaphrodites from a skin biopsy. Surg Gynecol Obstet. 1953 Jun;96(6):641–648. [PubMed] [Google Scholar]
  24. MOSIER H. D., SCOTT L. W., COTTER L. H. The frequency of the positive sex-chromatin pattern in males with mental deficiency. Pediatrics. 1960 Feb;25:291–297. [PubMed] [Google Scholar]
  25. OHNO S., HAUSCHKA T. S. Allocycly of the X-chromosome in tumors and normal tissues. Cancer Res. 1960 May;20:541–545. [PubMed] [Google Scholar]
  26. OHNO S., KAPLAN W. D., KINOSITA R. Formation of the sex chromatin by a single X-chromosome in liver cells of Rattus norvegicus. Exp Cell Res. 1959 Oct;18:415–418. doi: 10.1016/0014-4827(59)90031-x. [DOI] [PubMed] [Google Scholar]
  27. PASQUALINI R. Q., VIDAL G., BUR G. E. Psychopathology of Klinefelter's syndrome; review of thirty-one cases. Lancet. 1957 Jul 27;273(6987):164–167. doi: 10.1016/s0140-6736(57)90616-5. [DOI] [PubMed] [Google Scholar]
  28. PRADER A., SCHNEIDER J., ZUBLIN W., FRANCES J. M., RUEDI K. Die Häufigkeit des echten, chromatin-positiven Klinefelter-Syndroms und seine Beziehungen zum Schwachsinn. Schweiz Med Wochenschr. 1958 Sep 20;88(38):917–920. [PubMed] [Google Scholar]
  29. PUCK T. T., CIECIURA S. J., ROBINSON A. Genetics of somatic mammalian cells. III. Long-term cultivation of euploid cells from human and animal subjects. J Exp Med. 1958 Dec 1;108(6):945–956. doi: 10.1084/jem.108.6.945. [DOI] [PMC free article] [PubMed] [Google Scholar]
  30. SIEBENMANN R., PRADER A. Das echte Klinefelter-Syndrom vor der Pubertät. Schweiz Med Wochenschr. 1958 Jun 21;88(25):607–610. [PubMed] [Google Scholar]
  31. Tjio J. H., Puck T. T., Robinson A. THE SOMATIC CHROMOSOMAL CONSTITUTION OF SOME HUMAN SUBJECTS WITH GENETIC DEFECTS. Proc Natl Acad Sci U S A. 1959 Jul;45(7):1008–1016. doi: 10.1073/pnas.45.7.1008. [DOI] [PMC free article] [PubMed] [Google Scholar]
  32. ZUBLIN W. Zur Psychologie des Klinefelter-Syndroms. Acta Endocrinol (Copenh) 1953 Oct;14(2):137–144. [PubMed] [Google Scholar]

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