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Canadian Medical Association Journal logoLink to Canadian Medical Association Journal
. 1973 May 5;108(9):1111–1115.

The frequency of genetic disease and congenital malformation among patients in a pediatric hospital

C R Scriver, J L Neal, R Saginur, A Clow
PMCID: PMC1941389  PMID: 4704890

Abstract

A sample of 12,801 admissions to a pediatric hospital was surveyed in 1969-70 to determine the prevalence of disease which could be classified as “genetic” in origin or related to “congenital malformation”.

“Genetic” admissions accounted for 11.1% of the total while 18.5% were for congenital malformations; about 2% (unknown group) were probably genetic. Therefore about one third of all admissions represent the effect of abnormal gene-environment interrelations at some point in the development or life of the patient.

The “genetic” patient is admitted more often to a medical service while the patient with congenital malformation usually goes to a surgical service; the former stays 7.3 days and the latter 8.6 days. A disproportionate number of patients staying longer than 10 days were found in the group with congenital malformations. Seventy percent of the patients with multiple admissions (3.2% of all admissions) have genetic illness or congenital malformation.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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