Skip to main content
The American Journal of Pathology logoLink to The American Journal of Pathology
. 1963 Mar;42(3):271–283.

Prevention by Cortisone of the Changes in Cartilage Induced by an Excess of Vitamin a in Rabbits

Lewis Thomas, Robert T McCluskey, John Li, Gerald Weissmann
PMCID: PMC1949685  PMID: 13981092

Full text

PDF
276

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. FELL H. B., DINGLE J. T., WEBB M. Studies on the mode of action of excess of vitamin A. 4. The specificity of the effect on embryonic chick-limb cartilage in culture and on isolated rat-liver lysosomes. Biochem J. 1962 Apr;83:63–69. doi: 10.1042/bj0830063. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. FELL H. B., MELLANBY E. The effect of hypervitaminosis A on embryonic limb bones cultivated in vitro. J Physiol. 1952 Mar;116(3):320–349. doi: 10.1113/jphysiol.1952.sp004708. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. FELL H. B., THOMAS L. Comparison of the effects of papain and vitamin A on cartilage. II. The effects on organ cultures of embryonic skeletal tissue. J Exp Med. 1960 May 1;111:719–744. doi: 10.1084/jem.111.5.719. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. FELL H. B., THOMAS L. The influence of hydrocortisone on the action of excess vitamin A on limb bone rudiments in culture. J Exp Med. 1961 Sep 1;114:343–362. doi: 10.1084/jem.114.3.343. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. KRAMER H., WINDRUM G. M. The metachromatic staining reaction. J Histochem Cytochem. 1955 May;3(3):227–237. doi: 10.1177/3.3.227. [DOI] [PubMed] [Google Scholar]
  6. MCGILLIVRAY W. A. Some factors influencing the release of vitamin A from the liver. Br J Nutr. 1961;15:305–312. doi: 10.1079/bjn19610040. [DOI] [PubMed] [Google Scholar]
  7. McCLUSKEY R. T., THOMAS L. The removal of cartilage matrix in vivo by papain; prevention of recovery with cortisone, hydrocortisone and prednisoione by a direct action on cartilage. Am J Pathol. 1959 Jul-Aug;35(4):819–833. [PMC free article] [PubMed] [Google Scholar]
  8. SELYE H. Sensitization of the skeleton to vitamin-A overdosage by cortisol. Arthritis Rheum. 1958 Feb;1(1):87–90. doi: 10.1002/art.1780010113. [DOI] [PubMed] [Google Scholar]
  9. THOMAS L., McCLUSKEY R. T., POTTER J. L., WEISSMANN G. Comparison of the effects of papain n vitamin A on cartilage. I. The effects in rabbits. J Exp Med. 1960 May 1;111:705–718. doi: 10.1084/jem.111.5.705. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. THOMAS L. Reversible collapse of rabbit ears after intravenous papain, and prevention of recovery by cortisone. J Exp Med. 1956 Aug 1;104(2):245–252. doi: 10.1084/jem.104.2.245. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. WANG P., GLASS H. L., GOLDENBERG L., STEARNS G., KELLY H. G., JACKSON R. L. Serum vitamin A and carotene levels in children with rheumatic fever. AMA Am J Dis Child. 1954 Jun;87(6):659–672. doi: 10.1001/archpedi.1954.02050090647001. [DOI] [PubMed] [Google Scholar]
  12. WEISSMANN G., DINGLE J. Release of lysosomal protease by ultraviolet irradiation and inhibition by hydrocortisone. Exp Cell Res. 1961 Oct;25:207–210. doi: 10.1016/0014-4827(61)90328-7. [DOI] [PubMed] [Google Scholar]
  13. WEISSMANN G., THOMAS L. Studies on lysosomes. I. The effects of endotoxin, endotoxin tolerance, and cortisone on the release of acid hydrolases from a granular fraction of rabbit liver. J Exp Med. 1962 Oct 1;116:433–450. doi: 10.1084/jem.116.4.433. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. WOLF G. Some thoughts on the metabolic role of vitamin A. Nutr Rev. 1962 Jun;20:161–163. doi: 10.1111/j.1753-4887.1962.tb04603.x. [DOI] [PubMed] [Google Scholar]

Articles from The American Journal of Pathology are provided here courtesy of American Society for Investigative Pathology

RESOURCES