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. 1974 Dec 21;111(12):1309–1311.

Cardiovascular manifestations of ankylosing spondylitis

T Douglas Kinsella, Louis G Johnson, R Ian Sutherland
PMCID: PMC1955968  PMID: 4442013

Abstract

The incidence of cardiovascular lesions in 97 patients with ankylosing spondylitis (AS) was found to be 14%; 8 patients had isolated aortic insufficiency (AI), 3 had isolated heart block, 2 had combined AI and heart block, and 1 had mitral insufficiency. In comparison with control groups of 81 patients with rheumatoid arthritis and 99 random hospital patients there was no increased incidence of isolated heart block in patients with AS. Clinical and postmortem findings indicated that the cardiovascular lesions of some patients with AS may antedate articular disease and may regress spontaneously. In addition, the unusual occurrence of AI in two patients with psoriatic spondylitis and in one with AS and regional enteritis is documented.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BERNSTEIN L. Cardiac complications in spondylarthritis ankylopoietica. Rheumatism. 1951 Apr;7(2):18–23. [PubMed] [Google Scholar]
  2. Bulkley B. H., Roberts W. C. Ankylosing spondylitis and aortic regurgitation. Description of the characteristic cardiovascular lesion from study of eight necropsy patients. Circulation. 1973 Nov;48(5):1014–1027. doi: 10.1161/01.cir.48.5.1014. [DOI] [PubMed] [Google Scholar]
  3. Böttiger L. E., Edhag O. Heart block in ankylosing spondylitis and uropolyarthritis. Br Heart J. 1972 May;34(5):487–492. doi: 10.1136/hrt.34.5.487. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Calabro J. J., Maltz B. A. Ankylosing spondylitis. N Engl J Med. 1970 Mar 12;282(11):606–610. doi: 10.1056/NEJM197003122821107. [DOI] [PubMed] [Google Scholar]
  5. GRAHAM D. C., SMYTHE H. A. The carditis and aortitis of ankylosing spondylitis. Bull Rheum Dis. 1958 Nov;9(3):171–174. [PubMed] [Google Scholar]
  6. Hart F. D. Ankylosing spondylitis. Lancet. 1968 Dec 21;2(7582):1340–1344. doi: 10.1016/s0140-6736(68)91832-1. [DOI] [PubMed] [Google Scholar]
  7. Johnson W. L., Toone E. The clinical and pathological cardiac manifestations of rheumatoid spondylitis. Va Med Mon (1918) 1968 Mar;95(3):132–140. [PubMed] [Google Scholar]
  8. Kinsella T. D., MacDonald R. F., Johnson L. G. Ankylosing spondylitis: a late re-evaluation of 92 cases. Can Med Assoc J. 1966 Jul 2;95(1):1–9. [PMC free article] [PubMed] [Google Scholar]
  9. Ogryzlo M. A., Rosen P. S. Ankylosing (Marie-Strümpell) spondylitis. Postgrad Med. 1969 Jan;45(1):182–188. doi: 10.1080/00325481.1969.11696994. [DOI] [PubMed] [Google Scholar]
  10. REED W. B., BECKER S. W., ROHDE R., HEISKELL C. L. Psoriasis and arthritis. Clinicopathologic study. Arch Dermatol. 1961 Apr;83:541–548. doi: 10.1001/archderm.1961.01580100005001. [DOI] [PubMed] [Google Scholar]
  11. Roberts W. C., Hollingsworth J. F., Bulkley B. H., Jaffe R. B., Epstein S. E., Stinson E. B. Combined mitral and aortic regurgitation in ankylosing spondylitis. Angiographic and anatomic features. Am J Med. 1974 Feb;56(2):237–243. doi: 10.1016/0002-9343(74)90602-0. [DOI] [PubMed] [Google Scholar]
  12. Swezey R. L., Bjarnason D. M., Alexander S. J., Forrester D. B. Resorptive arthropathy and the opera-glass hand syndrome. Semin Arthritis Rheum. 1972;2(3):191–244. doi: 10.1016/0049-0172(72)90009-1. [DOI] [PubMed] [Google Scholar]
  13. TOONE E. C., Jr, PIERCE E. L., HENNIGAR G. R. Aortitis and aortic regurgitation associated with rheumatoid spondylitis. Am J Med. 1959 Feb;26(2):255–263. doi: 10.1016/0002-9343(59)90315-8. [DOI] [PubMed] [Google Scholar]

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