Abstract
Summary: Atypical mycobacterial infections may give rise to various clinical difficulties. Case reports of six patients--three adult patients with pulmonary lesions, two children with cervical lymphadentis and one patient in whom the atypical mycobacterium appeared to be present as a commensal--illustrate these difficulties. Determination of the significance of the organism and differentiation of condition from tuberculosis and others requires consideration of the clinical picture, the results of skin testing, histologic features and cultural characteristics. Three patients, including the two children, were treated with a combination of surgery and chemotherapy, with satisfactory results. An elderly patient with chronic bronchitis and a pulmonary infection due to M. kansasii was treated successfully with antiuberculosis agents alone. Chemotherapy is being tried on a fifth patient with cavitary disease due to M. intracellulare, but is seems likely that an operation will also be required.
Full text
PDF
Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- BLACK B. G., CHAPMAN J. S. CERVICAL ADENITIS IN CHILDREN DUE TO HUMAN AND UNCLASSIFIED MYCOBACTERIA. Pediatrics. 1964 Jun;33:887–893. [PubMed] [Google Scholar]
- Fischer D. A., Lester W., Schaefer W. B. Infections with atypical mycobacteria. Five years' experience at the National Jewish Hospital. Am Rev Respir Dis. 1968 Jul;98(1):29–34. doi: 10.1164/arrd.1968.98.1.29. [DOI] [PubMed] [Google Scholar]
- Goldman K. P. Treatment of unclassified mycobacterial infection of the lungs. Thorax. 1968 Jan;23(1):94–99. doi: 10.1136/thx.23.1.94. [DOI] [PMC free article] [PubMed] [Google Scholar]
- HSU K. H. Nontuberculosis mycobacterial infections in children. A preliminary clinical and epidemiologic study. J Pediatr. 1962 May;60:705–710. doi: 10.1016/s0022-3476(62)80096-1. [DOI] [PubMed] [Google Scholar]
- Kubica G. P. Differential identification of mycobacteria. VII. Key features for identification of clinically significant mycobacteria. Am Rev Respir Dis. 1973 Jan;107(1):9–21. doi: 10.1164/arrd.1973.107.1.9. [DOI] [PubMed] [Google Scholar]
- Lincoln E. M., Gilbert L. A. Disease in children due to mycobacteria other than Mycobacterium tuberculosis. Am Rev Respir Dis. 1972 May;105(5):683–714. doi: 10.1164/arrd.1972.105.5.683. [DOI] [PubMed] [Google Scholar]
- RUNYON E. H. Anonymous mycobacteria in pulmonary disease. Med Clin North Am. 1959 Jan;43(1):273–290. doi: 10.1016/s0025-7125(16)34193-1. [DOI] [PubMed] [Google Scholar]
- Rynearson T. K., Shronts J. S., Wolinsky E. Rifampin: in vitro effect on atypical mycobacteria. Am Rev Respir Dis. 1971 Aug;104(2):272–274. doi: 10.1164/arrd.1971.104.2.272. [DOI] [PubMed] [Google Scholar]
- Woodruff C. E., Chapman P. T. Tuberculin sensitivity in elderly patients. Am Rev Respir Dis. 1971 Aug;104(2):261–263. doi: 10.1164/arrd.1971.104.2.261. [DOI] [PubMed] [Google Scholar]