Skip to main content
PMC home page
Canadian Medical Association Journal logoLink to Canadian Medical Association Journal
. 1975 Sep 6;113(5):410–412.

Autonomic neuropathy and carcinoma of the lung.

M N Ahmed, S Carpenter
PMCID: PMC1956659  PMID: 168952

Abstract

A patient who died from oat-cell carcinoma of the lung had had abdominal pain and obstipation. Autopsy revealed autonomic neuropathy limited to the gastrointestinal tract, which was considered to be related to carcinoma as a remote effect. This interpretation was further supported by the presence of Wallerian degeneration of the dorsal columns. Autonomic neuropathy involving the gastrointestinal tract in association with malignant disease has not been previously described.

Full text

PDF
412

Images in this article

410FIG. 1
on p.410
411FIG. 2
on p.411
411FIG. 3
on p.411
412FIG. 4
on p.412

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Andersen O., Lindberg J., Modigh K., Reske-Nielsen E. Subacute dysautonomia with incomplete recovery. Acta Neurol Scand. 1972;48(4):510–519. doi: 10.1111/j.1600-0404.1972.tb07570.x. [DOI] [PubMed] [Google Scholar]
  2. Appenzeller O., Arnason B. G., Adams R. D. Experimental autonomic neuropathy: an immunologically induced disorder of reflex vasomotor function. J Neurol Neurosurg Psychiatry. 1965 Dec;28(6):510–515. doi: 10.1136/jnnp.28.6.510. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Appenzeller O., Kornfeld M. Acute pandysautonomia. Clinical and morphologic study. Arch Neurol. 1973 Nov;29(5):334–339. doi: 10.1001/archneur.1973.00490290074010. [DOI] [PubMed] [Google Scholar]
  4. Asbury A. K., Arnason B. G., Adams R. D. The inflammatory lesion in idiopathic polyneuritis. Its role in pathogenesis. Medicine (Baltimore) 1969 May;48(3):173–215. doi: 10.1097/00005792-196905000-00001. [DOI] [PubMed] [Google Scholar]
  5. DUNLOP J. A. Ogilvie's syndrome of false colonic obstruction; a case with post-mortem findings. Br Med J. 1949 May 21;1(4611):890–890. doi: 10.1136/bmj.1.4611.890. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Dayan A. D., Croft P. B., Wilkinson M. Association of carcinomatous neuromyopathy with different histological types of carcinoma of the lung. Brain. 1965 Sep;88(3):435–448. doi: 10.1093/brain/88.3.435. [DOI] [PubMed] [Google Scholar]
  7. Dyck P. J., Lambert E. H. Dissociated sensation in amylidosis. Compound action potential, quantitative histologic and teased-fiber, and electron microscopic studies of sural nerve biopsies. Arch Neurol. 1969 May;20(5):490–507. doi: 10.1001/archneur.1969.00480110054005. [DOI] [PubMed] [Google Scholar]
  8. Goulon M., Nouailhat F., Grosbuis S., Gajdos P. Hypotension orthostatique à pouls invariable. Etude hémodynamique d'une neuropathie amyloïde et d'une forme idiopathique transitoire. Rev Neurol (Paris) 1971 Oct;125(4):257–272. [PubMed] [Google Scholar]
  9. HEATHFIELD K. W., WILLIAMS J. R. Peripheral neuropathy and myopathy associated with bronchogenic carcinoma. Brain. 1954;77(1):122–137. doi: 10.1093/brain/77.1.122. [DOI] [PubMed] [Google Scholar]
  10. Henson R. A., Hoffman H. L., Urich H. Encephalomyelitis with carcinoma. Brain. 1965 Sep;88(3):449–464. doi: 10.1093/brain/88.3.449. [DOI] [PubMed] [Google Scholar]
  11. MULDER D. W., LAMBERT E. H., BASTRON J. A., SPRAGUE R. G. The neuropathies associated with diabetes mellitus. A clinical and electromyographic study of 103 unselected diabetic patients. Neurology. 1961 Apr;11(4):275–284. doi: 10.1212/wnl.11.4.275. [DOI] [PubMed] [Google Scholar]
  12. Matsuyama H., Haymaker W. Distribution of lesions in the Landry-Guillain-Barré syndrome, with emphasis on involvement of the sympathetic system. Acta Neuropathol. 1967 May 5;8(3):230–241. doi: 10.1007/BF00688825. [DOI] [PubMed] [Google Scholar]
  13. OGILVIE H. Large-intestine colic due to sympathetic deprivation; a new clinical syndrome. Br Med J. 1948 Oct 9;2(4579):671–673. doi: 10.1136/bmj.2.4579.671. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Okada F., Yamashita I., Suwa N. Two cases of acute pandysautonomia. Arch Neurol. 1975 Mar;32(3):146–151. doi: 10.1001/archneur.1975.00490450026002. [DOI] [PubMed] [Google Scholar]
  15. Quinlan C. D. Autonomic neuropathy in carcinoma of the lung. J Ir Med Assoc. 1971 Sep;64(418):430–431. [PubMed] [Google Scholar]
  16. Thomas J. P., Shields R. Associated autonomic dysfunction and carcinoma of the pancreas. Br Med J. 1970 Oct 3;4(5726):32–32. doi: 10.1136/bmj.4.5726.32. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Thomashefsky A. J., Horwitz S. J., Feingold M. H. Acute autonomic neuropathy. Neurology. 1972 Mar;22(3):251–255. doi: 10.1212/wnl.22.3.251. [DOI] [PubMed] [Google Scholar]
  18. Young R. R., Asbury A. K., Adams R. D., Corbett J. L. Pure pan-dysautonomia with recovery. Trans Am Neurol Assoc. 1969;94:355–357. [PubMed] [Google Scholar]

Articles from Canadian Medical Association Journal are provided here courtesy of Canadian Medical Association

RESOURCES