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. 1994 Dec;176(23):7383–7386. doi: 10.1128/jb.176.23.7383-7386.1994

Regulation of lysyl-tRNA synthetase expression by histone-like protein H-NS of Escherichia coli.

K Ito 1, T Oshima 1, T Mizuno 1, Y Nakamura 1
PMCID: PMC197130  PMID: 7961513

Abstract

The lysU gene encoding lysyl-tRNA synthetase of Escherichia coli is normally silent at low temperatures and is expressed by certain metabolites and stimuli. A novel class of lysU-constitutive mutations were isolated by random insertion mutagenesis. These mutations nullified the hns gene encoding a histone-like protein, H-NS, and affected thermoregulation of lysU.

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Selected References

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