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editorial
. 1991 Jan;63(1):9–12. doi: 10.1038/bjc.1991.4

Identification of genes controlling metastatic behaviour.

I R Hart, D Easty
PMCID: PMC1971648  PMID: 1989670

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Ananthaswamy H. N., Price J. E., Goldberg L. H., Bales E. S. Simultaneous transfer of tumorigenic and metastatic phenotypes by transfection with genomic DNA from a human cutaneous squamous cell carcinoma. J Cell Biochem. 1988 Feb;36(2):137–146. doi: 10.1002/jcb.240360205. [DOI] [PubMed] [Google Scholar]
  2. Ananthaswamy H. N., Price J. E., Tainsky M. A., Goldberg L. H., Bales E. S. Correlation between Ha-ras gene amplification and spontaneous metastasis in NIH 3T3 cells transfected with genomic DNA from human skin cancers. Clin Exp Metastasis. 1989 May-Jun;7(3):301–313. doi: 10.1007/BF01753682. [DOI] [PubMed] [Google Scholar]
  3. Bevilacqua G., Sobel M. E., Liotta L. A., Steeg P. S. Association of low nm23 RNA levels in human primary infiltrating ductal breast carcinomas with lymph node involvement and other histopathological indicators of high metastatic potential. Cancer Res. 1989 Sep 15;49(18):5185–5190. [PubMed] [Google Scholar]
  4. Bradley M. O., Kraynak A. R., Storer R. D., Gibbs J. B. Experimental metastasis in nude mice of NIH 3T3 cells containing various ras genes. Proc Natl Acad Sci U S A. 1986 Jul;83(14):5277–5281. doi: 10.1073/pnas.83.14.5277. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Collier I. E., Wilhelm S. M., Eisen A. Z., Marmer B. L., Grant G. A., Seltzer J. L., Kronberger A., He C. S., Bauer E. A., Goldberg G. I. H-ras oncogene-transformed human bronchial epithelial cells (TBE-1) secrete a single metalloprotease capable of degrading basement membrane collagen. J Biol Chem. 1988 May 15;263(14):6579–6587. [PubMed] [Google Scholar]
  6. Dear T. N., McDonald D. A., Kefford R. F. Transcriptional down-regulation of a rat gene, WDNM2, in metastatic DMBA-8 cells. Cancer Res. 1989 Oct 1;49(19):5323–5328. [PubMed] [Google Scholar]
  7. Dear T. N., Ramshaw I. A., Kefford R. F. Differential expression of a novel gene, WDNM1, in nonmetastatic rat mammary adenocarcinoma cells. Cancer Res. 1988 Sep 15;48(18):5203–5209. [PubMed] [Google Scholar]
  8. Dear T. N. Re: T. Neil Dear et al., Transcriptional down-regulation of a rat gene, WDNM2, in metastatic DMBA-8 cells. Cancer Res., 49: 5323-5328, 1989. Cancer Res. 1990 Mar 1;50(5):1667–1667. [PubMed] [Google Scholar]
  9. Denhardt D. T., Greenberg A. H., Egan S. E., Hamilton R. T., Wright J. A. Cysteine proteinase cathepsin L expression correlates closely with the metastatic potential of H-ras-transformed murine fibroblasts. Oncogene. 1987;2(1):55–59. [PubMed] [Google Scholar]
  10. Ebralidze A., Tulchinsky E., Grigorian M., Afanasyeva A., Senin V., Revazova E., Lukanidin E. Isolation and characterization of a gene specifically expressed in different metastatic cells and whose deduced gene product has a high degree of homology to a Ca2+-binding protein family. Genes Dev. 1989 Jul;3(7):1086–1093. doi: 10.1101/gad.3.7.1086. [DOI] [PubMed] [Google Scholar]
  11. Egan S. E., McClarty G. A., Jarolim L., Wright J. A., Spiro I., Hager G., Greenberg A. H. Expression of H-ras correlates with metastatic potential: evidence for direct regulation of the metastatic phenotype in 10T1/2 and NIH 3T3 cells. Mol Cell Biol. 1987 Feb;7(2):830–837. doi: 10.1128/mcb.7.2.830. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Egan S. E., Wright J. A., Jarolim L., Yanagihara K., Bassin R. H., Greenberg A. H. Transformation by oncogenes encoding protein kinases induces the metastatic phenotype. Science. 1987 Oct 9;238(4824):202–205. doi: 10.1126/science.3659911. [DOI] [PubMed] [Google Scholar]
  13. Elvin P., Kerr I. B., McArdle C. S., Birnie G. D. Isolation and preliminary characterisation of cDNA clones representing mRNAs associated with tumour progression and metastasis in colorectal cancer. Br J Cancer. 1988 Jan;57(1):36–42. doi: 10.1038/bjc.1988.5. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Fearon E. R., Vogelstein B. A genetic model for colorectal tumorigenesis. Cell. 1990 Jun 1;61(5):759–767. doi: 10.1016/0092-8674(90)90186-i. [DOI] [PubMed] [Google Scholar]
  15. Fidler I. J., Kripke M. L. Metastasis results from preexisting variant cells within a malignant tumor. Science. 1977 Aug 26;197(4306):893–895. doi: 10.1126/science.887927. [DOI] [PubMed] [Google Scholar]
  16. Garbisa S., Pozzatti R., Muschel R. J., Saffiotti U., Ballin M., Goldfarb R. H., Khoury G., Liotta L. A. Secretion of type IV collagenolytic protease and metastatic phenotype: induction by transfection with c-Ha-ras but not c-Ha-ras plus Ad2-E1a. Cancer Res. 1987 Mar 15;47(6):1523–1528. [PubMed] [Google Scholar]
  17. Greig R. G., Koestler T. P., Trainer D. L., Corwin S. P., Miles L., Kline T., Sweet R., Yokoyama S., Poste G. Tumorigenic and metastatic properties of "normal" and ras-transfected NIH/3T3 cells. Proc Natl Acad Sci U S A. 1985 Jun;82(11):3698–3701. doi: 10.1073/pnas.82.11.3698. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Hanahan D. Dissecting multistep tumorigenesis in transgenic mice. Annu Rev Genet. 1988;22:479–519. doi: 10.1146/annurev.ge.22.120188.002403. [DOI] [PubMed] [Google Scholar]
  19. Hart I. R., Goode N. T., Wilson R. E. Molecular aspects of the metastatic cascade. Biochim Biophys Acta. 1989 Jul 28;989(1):65–84. doi: 10.1016/0304-419x(89)90035-8. [DOI] [PubMed] [Google Scholar]
  20. Hedrick S. M., Cohen D. I., Nielsen E. A., Davis M. M. Isolation of cDNA clones encoding T cell-specific membrane-associated proteins. Nature. 1984 Mar 8;308(5955):149–153. doi: 10.1038/308149a0. [DOI] [PubMed] [Google Scholar]
  21. Hicks N. J., Ward R. V., Reynolds J. J. A fibrosarcoma model derived from mouse embryo cells: growth properties and secretion of collagenase and metalloproteinase inhibitor (TIMP) by tumour cell lines. Int J Cancer. 1984 Jun 15;33(6):835–844. doi: 10.1002/ijc.2910330620. [DOI] [PubMed] [Google Scholar]
  22. Johnson J. P., Lehmann J. M., Stade B. G., Rothbächer U., Sers C., Riethmüller G. Functional aspects of three molecules associated with metastasis development in human malignant melanoma. Invasion Metastasis. 1989;9(6):338–350. [PubMed] [Google Scholar]
  23. Kerbel R. S. Towards an understanding of the molecular basis of the metastatic phenotype. Invasion Metastasis. 1989;9(6):329–337. [PubMed] [Google Scholar]
  24. Kerbel R. S., Waghorne C., Korczak B., Lagarde A., Breitman M. L. Clonal dominance of primary tumours by metastatic cells: genetic analysis and biological implications. Cancer Surv. 1988;7(4):597–629. [PubMed] [Google Scholar]
  25. Khokha R., Waterhouse P., Yagel S., Lala P. K., Overall C. M., Norton G., Denhardt D. T. Antisense RNA-induced reduction in murine TIMP levels confers oncogenicity on Swiss 3T3 cells. Science. 1989 Feb 17;243(4893):947–950. doi: 10.1126/science.2465572. [DOI] [PubMed] [Google Scholar]
  26. Klein G., Klein E. Evolution of tumours and the impact of molecular oncology. Nature. 1985 May 16;315(6016):190–195. doi: 10.1038/315190a0. [DOI] [PubMed] [Google Scholar]
  27. Kohne D. E., Levison S. A., Byers M. J. Room temperature method for increasing the rate of DNA reassociation by many thousandfold: the phenol emulsion reassociation technique. Biochemistry. 1977 Nov 29;16(24):5329–5341. doi: 10.1021/bi00643a026. [DOI] [PubMed] [Google Scholar]
  28. Kyprianou N., Isaacs J. T. Relationship between metastatic ability and H-ras oncogene expression in rat mammary cancer cells transfected with the v-H-ras oncogene. Cancer Res. 1990 Mar 1;50(5):1449–1454. [PubMed] [Google Scholar]
  29. Lehmann J. M., Riethmüller G., Johnson J. P. MUC18, a marker of tumor progression in human melanoma, shows sequence similarity to the neural cell adhesion molecules of the immunoglobulin superfamily. Proc Natl Acad Sci U S A. 1989 Dec;86(24):9891–9895. doi: 10.1073/pnas.86.24.9891. [DOI] [PMC free article] [PubMed] [Google Scholar]
  30. Liotta L. A. Growth autonomy: the only requirement for metastasis? J Natl Cancer Inst. 1988 May 4;80(5):300–300. doi: 10.1093/jnci/80.5.300. [DOI] [PubMed] [Google Scholar]
  31. Matrisian L. M., Bowden G. T., Krieg P., Fürstenberger G., Briand J. P., Leroy P., Breathnach R. The mRNA coding for the secreted protease transin is expressed more abundantly in malignant than in benign tumors. Proc Natl Acad Sci U S A. 1986 Dec;83(24):9413–9417. doi: 10.1073/pnas.83.24.9413. [DOI] [PMC free article] [PubMed] [Google Scholar]
  32. Muschel R. J., Williams J. E., Lowy D. R., Liotta L. A. Harvey ras induction of metastatic potential depends upon oncogene activation and the type of recipient cell. Am J Pathol. 1985 Oct;121(1):1–8. [PMC free article] [PubMed] [Google Scholar]
  33. Nicolson G. L. Cancer metastasis: tumor cell and host organ properties important in metastasis to specific secondary sites. Biochim Biophys Acta. 1988 Nov 15;948(2):175–224. doi: 10.1016/0304-419x(88)90010-8. [DOI] [PubMed] [Google Scholar]
  34. Nowell P. C. The clonal evolution of tumor cell populations. Science. 1976 Oct 1;194(4260):23–28. doi: 10.1126/science.959840. [DOI] [PubMed] [Google Scholar]
  35. Phillips S. M., Bendall A. J., Ramshaw I. A. Isolation of gene associated with high metastatic potential in rat mammary adenocarcinomas. J Natl Cancer Inst. 1990 Feb 7;82(3):199–203. doi: 10.1093/jnci/82.3.199. [DOI] [PubMed] [Google Scholar]
  36. Radler-Pohl A., Pohl J., Schirrmacher V. Selective enhancement of metastatic capacity in mouse bladder carcinoma cells after transfection with DNA from liver metastases of human colon carcinoma. Int J Cancer. 1988 Jun 15;41(6):840–846. doi: 10.1002/ijc.2910410611. [DOI] [PubMed] [Google Scholar]
  37. Rich B. E., Steitz J. A. Human acidic ribosomal phosphoproteins P0, P1, and P2: analysis of cDNA clones, in vitro synthesis, and assembly. Mol Cell Biol. 1987 Nov;7(11):4065–4074. doi: 10.1128/mcb.7.11.4065. [DOI] [PMC free article] [PubMed] [Google Scholar]
  38. Rosengard A. M., Krutzsch H. C., Shearn A., Biggs J. R., Barker E., Margulies I. M., King C. R., Liotta L. A., Steeg P. S. Reduced Nm23/Awd protein in tumour metastasis and aberrant Drosophila development. Nature. 1989 Nov 9;342(6246):177–180. doi: 10.1038/342177a0. [DOI] [PubMed] [Google Scholar]
  39. Schalken J. A., Ebeling S. B., Isaacs J. T., Treiger B., Bussemakers M. J., de Jong M. E., Van de Ven W. J. Down modulation of fibronectin messenger RNA in metastasizing rat prostatic cancer cells revealed by differential hybridization analysis. Cancer Res. 1988 Apr 15;48(8):2042–2046. [PubMed] [Google Scholar]
  40. Sharp M. G., Adams S. M., Elvin P., Walker R. A., Brammar W. J., Varley J. M. A sequence previously identified as metastasis-related encodes an acidic ribosomal phosphoprotein, P2. Br J Cancer. 1990 Jan;61(1):83–88. doi: 10.1038/bjc.1990.19. [DOI] [PMC free article] [PubMed] [Google Scholar]
  41. Sobel M. E. Metastasis suppressor genes. J Natl Cancer Inst. 1990 Feb 21;82(4):267–276. doi: 10.1093/jnci/82.4.267. [DOI] [PubMed] [Google Scholar]
  42. Steeg P. S., Bevilacqua G., Kopper L., Thorgeirsson U. P., Talmadge J. E., Liotta L. A., Sobel M. E. Evidence for a novel gene associated with low tumor metastatic potential. J Natl Cancer Inst. 1988 Apr 6;80(3):200–204. doi: 10.1093/jnci/80.3.200. [DOI] [PubMed] [Google Scholar]
  43. Thorgeirsson U. P., Turpeenniemi-Hujanen T., Williams J. E., Westin E. H., Heilman C. A., Talmadge J. E., Liotta L. A. NIH/3T3 cells transfected with human tumor DNA containing activated ras oncogenes express the metastatic phenotype in nude mice. Mol Cell Biol. 1985 Jan;5(1):259–262. doi: 10.1128/mcb.5.1.259. [DOI] [PMC free article] [PubMed] [Google Scholar]
  44. Treiger B., Isaacs J. Expression of a transfected v-Harvey-ras oncogene in a Dunning rat prostate adenocarcinoma and the development of high metastatic ability. J Urol. 1988 Dec;140(6):1580–1586. doi: 10.1016/s0022-5347(17)42131-8. [DOI] [PubMed] [Google Scholar]
  45. Tulchinsky E. M., Grigorian M. S., Ebralidze A. K., Milshina N. I., Lukanidin E. M. Structure of gene mts1, transcribed in metastatic mouse tumor cells. Gene. 1990 Mar 15;87(2):219–223. doi: 10.1016/0378-1119(90)90305-b. [DOI] [PubMed] [Google Scholar]
  46. Wallet V., Mutzel R., Troll H., Barzu O., Wurster B., Veron M., Lacombe M. L. Dictyostelium nucleoside diphosphate kinase highly homologous to Nm23 and Awd proteins involved in mammalian tumor metastasis and Drosophila development. J Natl Cancer Inst. 1990 Jul 18;82(14):1199–1202. doi: 10.1093/jnci/82.14.1199. [DOI] [PubMed] [Google Scholar]

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