Abstract
In a house-to-house survey in Ernakulam district, Kerala, India, 12,213 tobacco users were interviewed about the details of their tobacco usage and examined for the presence of leukoplakia. The frequency of tobacco habit was associated with the prevalence of leukoplakia indicating a positive dose-response relationship. The dose-response relationship remained significant, taking age, sex, and the type of tobacco habit into account. After adjusting for all these variables jointly the association still remained significant. The dose-response relationship was stronger for the smoking habit than for the chewing habit. A weaker relationship in the chewing habit was not due to the duration of chewing habit or the habit of retaining the betel quid in the mouth while sleeping. Thus the dose-response relationship, although significant, was different for tobacco smoking and chewing habits.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Baric J. M., Alman J. E., Feldman R. S., Chauncey H. H. Influence of cigarette, pipe, and cigar smoking, removable partial dentures, and age on oral leukoplakia. Oral Surg Oral Med Oral Pathol. 1982 Oct;54(4):424–429. doi: 10.1016/0030-4220(82)90389-9. [DOI] [PubMed] [Google Scholar]
- Dayal P. K., Mani N. J., Bhargava K. Prevalence of oral cancer and precancerous lesions in 'pan'/'supari' chewers. Indian J Public Health. 1978 Jul-Sep;22(3):234–245. [PubMed] [Google Scholar]
- Mehta F. S., Gupta M. B., Pindborg J. J., Bhonsle R. B., Jalnawalla P. N., Sinor P. N. An intervention study of oral cancer and precancer in rural Indian populations: a preliminary report. Bull World Health Organ. 1982;60(3):441–446. [PMC free article] [PubMed] [Google Scholar]
- Mehta F. S., Gupta P. C., Daftary D. K., Pindborg J. J., Choksi S. K. An epidemiologic study of oral cancer and precancerous conditions among 101,761 villagers in Maharashtra, India. Int J Cancer. 1972 Jul 15;10(1):134–141. doi: 10.1002/ijc.2910100118. [DOI] [PubMed] [Google Scholar]
- Mehta F. S., Pindborg J. J., Gupta P. C., Daftary D. K. Epidemiologic and histologic study of oral cancer and leukoplakia among 50,915 villagers in India. Cancer. 1969 Oct;24(4):832–849. doi: 10.1002/1097-0142(196910)24:4<832::aid-cncr2820240427>3.0.co;2-u. [DOI] [PubMed] [Google Scholar]
- Mehta F. S., Shroff B. C., Gupta P. C., Daftary D. K. Oral leukoplakia in relation to tobacco habits. A ten-year follow-up study of Bombay policemen. Oral Surg Oral Med Oral Pathol. 1972 Sep;34(3):426–433. doi: 10.1016/0030-4220(72)90319-2. [DOI] [PubMed] [Google Scholar]
- Pindborg J. J., Barmes D., Roed-Petersen B. Epidemiology and histology of oral leukoplakia and leukoedema among Papuans and New Guineans. Cancer. 1968 Aug;22(2):379–384. doi: 10.1002/1097-0142(196808)22:2<379::aid-cncr2820220215>3.0.co;2-a. [DOI] [PubMed] [Google Scholar]
- Pindborg J. J., Kiaer J., Gupta P. C., Chawla T. N. Studies in oral leukoplakias. Prevalence of leukoplakia among 10,000 persons in Lucknow, India, with special reference to use of tobacco and betel nut. Bull World Health Organ. 1967;37(1):109–116. [PMC free article] [PubMed] [Google Scholar]
- Roed-Petersen B., Gupta P. C., Pindborg J. J., Singh B. Association between oral leukoplakia and sex, age, and tobacco habits. Bull World Health Organ. 1972;47(1):13–19. [PMC free article] [PubMed] [Google Scholar]