Abstract
Tests in three patients with asthma occurring only on exertion showed that F.E.V.1 fell progressively on exercise, to reach a minimum after 10 minutes. All patients showed a striking metabolic acidosis, with an accumulation of the products of anaerobic metabolism.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- BLUMENTHAL J. S., BROWN E. B., CAMPBELL G. S. Molar sodium lactate in acute epinephrine-fast asthmatic patients. Ann Allergy. 1956 Nov-Dec;14(6):506–510. [PubMed] [Google Scholar]
- Crompton G. K. An unusual example of exercise-induced asthma. Thorax. 1968 Mar;23(2):165–167. doi: 10.1136/thx.23.2.165. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Davies S. E. Effect of disodium cromoglycate on exercise-induced asthma. Br Med J. 1968 Sep 7;3(5618):593–594. doi: 10.1136/bmj.3.5618.593. [DOI] [PMC free article] [PubMed] [Google Scholar]
- HUCKABEE W. E. Relationships of pyruvate and lactate during anaerobic metabolism. III. Effect of breathing low-oxygen gases. J Clin Invest. 1958 Feb;37(2):264–271. doi: 10.1172/JCI103605. [DOI] [PMC free article] [PubMed] [Google Scholar]
- JONES R. S., WHARTON M. J., BUSTON M. H. THE PLACE OF PHYSICAL EXERCISE AND BRONCHODILATOR DRUGS IN THE ASSESSMENT OF THE ASTHMATIC CHILD. Arch Dis Child. 1963 Dec;38:539–545. doi: 10.1136/adc.38.202.539. [DOI] [PMC free article] [PubMed] [Google Scholar]
- MITHOEFER J. C., RUNSER R. H., KARETZKY M. S. THE USE OF SODIUM BICARBONATE IN THE TREATMENT OF ACUTE BRONCHIAL ASTHMA. N Engl J Med. 1965 Jun 10;272:1200–1203. doi: 10.1056/NEJM196506102722303. [DOI] [PubMed] [Google Scholar]
- McNeill R. S., Nairn J. R., Millar J. S., Ingram C. G. Exercise-induced asthma. Q J Med. 1966 Jan;35(137):55–67. [PubMed] [Google Scholar]
- Rebuck A. S., Read J. Exercise-induced asthma. Lancet. 1968 Aug 24;2(7565):429–431. doi: 10.1016/s0140-6736(68)90468-6. [DOI] [PubMed] [Google Scholar]