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. 1970 Dec;24(4):843–848. doi: 10.1038/bjc.1970.99

The Structure of Tumours Derived from Mouse Cells after “Spontaneous” Transformation in vitro

L M Franks, F C Chesterman, C Rowlatt
PMCID: PMC2008703  PMID: 5533949

Abstract

The histological structure of 58 primary tumours derived from spontaneously transformed tissue culture cell lines from embryonic (14-16 days), young (3-20 days) and old (28-34 months) C3H and C57 mice is described. Although the cell lines were derived from a number of different organs the tumours were similar in morphology. The pattern was mixed, with “fibrosarcomatous”, “myxoid”, “epithelioid” and giant cell areas. The tumours resemble some types of haemangiopericytoma.

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Selected References

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