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. 1970 Dec;24(4):853–860. doi: 10.1038/bjc.1970.101

Studies of the Rat Immune Response to Plasmacytoma 5563 in C3H Mice

O Fakhri, J R Hobbs
PMCID: PMC2008713  PMID: 5503607

Abstract

Washed lymphocytes from immunized rats showed no reaction against mouse plasmacytoma 5563 in vivo or in vitro.

Cell-free lymph from immunized rats was shown to be cytotoxic to the tumour cells in vitro. This effect we have shown to be solely in the 19s fraction after Sephadex G-200 separation.

This 19s fraction conferred partial protection to tumour bearing mice when given shortly after transplantation, but had negligible effect against late well established tumour.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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