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. 1987 Aug;53(8):1965–1968. doi: 10.1128/aem.53.8.1965-1968.1987

Demonstration of mucosa-associated microbial populations in the colons of mice.

G W Tannock 1
PMCID: PMC204036  PMID: 3662524

Abstract

Gram-stained sections prepared in a microtome-cryostat and examined by light microscopy confirmed the observation with scanning electron microscopy made by other workers that microbes inhabit a zone adjacent to the mucosal surface of the proximal colon of mice. Microbes in the midcolon, in contrast, are restricted to the fecal pellets occupying the intestinal lumen.

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1967

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Selected References

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  1. Bollard J. E., Vanderwee M. A., Smith G. W., Tasman-Jones C., Gavin J. B., Lee S. P. Location of bacteria in the mid-colon of the rat. Appl Environ Microbiol. 1986 Mar;51(3):604–608. doi: 10.1128/aem.51.3.604-608.1986. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Dubos R. J., Savage D. C., Schaedler R. W. The indigenous flora of the gastrointestinal tract. Dis Colon Rectum. 1967 Jan-Feb;10(1):23–34. doi: 10.1007/BF02617382. [DOI] [PubMed] [Google Scholar]
  3. Lee A., Phillips M. Isolation and cultivation of spirochetes and other spiral-shaped bacteria associated with the cecal mucosa of rats and mice. Appl Environ Microbiol. 1978 Mar;35(3):610–613. doi: 10.1128/aem.35.3.610-613.1978. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Savage D. C., Blumershine R. V. Surface-surface associations in microbial communities populating epithelial habitats in the murine gastrointestinal ecosystem: scanning electron microscopy. Infect Immun. 1974 Jul;10(1):240–250. doi: 10.1128/iai.10.1.240-250.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Savage D. C., Dubos R., Schaedler R. W. The gastrointestinal epithelium and its autochthonous bacterial flora. J Exp Med. 1968 Jan 1;127(1):67–76. doi: 10.1084/jem.127.1.67. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Savage D. C., McAllister J. S., Davis C. P. Anaerobic bacteria on the mucosal epithelium of the murine large bowel. Infect Immun. 1971 Oct;4(4):492–502. doi: 10.1128/iai.4.4.492-502.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]

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